CA2666043C - Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise - Google Patents
Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise Download PDFInfo
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- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/483—NMR imaging systems with selection of signals or spectra from particular regions of the volume, e.g. in vivo spectroscopy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/563—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution of moving material, e.g. flow contrast angiography
- G01R33/56341—Diffusion imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
- A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
- A61B5/416—Evaluating particular organs or parts of the immune or lymphatic systems the spleen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4887—Locating particular structures in or on the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7235—Details of waveform analysis
- A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
- G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
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- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- High Energy & Nuclear Physics (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
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- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Radiology & Medical Imaging (AREA)
- Physiology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Signal Processing (AREA)
- Pulmonology (AREA)
- Dentistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Optics & Photonics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Abstract
L'invention concerne des procédés et des systèmes permettant d'évaluer l'échange gazeux pulmonaire et/ou l'état de la barrière alvéolo-capillaire par des techniques d'application d'impulsions d'écho de spin et d'obtenir au moins une image IRM 3D du 129Xe dissout dans les compartiments des globules rouges et des barrières dans les régions d'échange gazeux des poumons d'un patient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA3065182A CA3065182C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82798306P | 2006-10-03 | 2006-10-03 | |
| US60/827,983 | 2006-10-03 | ||
| PCT/US2007/021155 WO2008042370A1 (fr) | 2006-10-03 | 2007-10-02 | Systèmes et procédés permettant d'évaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarisé |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3065182A Division CA3065182C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2666043A1 CA2666043A1 (fr) | 2008-04-10 |
| CA2666043C true CA2666043C (fr) | 2020-02-25 |
Family
ID=39268769
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3152286A Active CA3152286C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
| CA3065182A Active CA3065182C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
| CA2666043A Active CA2666043C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3152286A Active CA3152286C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
| CA3065182A Active CA3065182C (fr) | 2006-10-03 | 2007-10-02 | Systemes et procedes permettant d'evaluer le transfert gazeux pulmonaire par irm avec du 129xe hyperpolarise |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20100027864A1 (fr) |
| EP (1) | EP2068709A4 (fr) |
| JP (1) | JP2010505516A (fr) |
| KR (1) | KR20090086396A (fr) |
| CN (1) | CN101553168A (fr) |
| AU (1) | AU2007305310B2 (fr) |
| BR (1) | BRPI0718198A2 (fr) |
| CA (3) | CA3152286C (fr) |
| NZ (1) | NZ575856A (fr) |
| RU (1) | RU2452372C2 (fr) |
| WO (1) | WO2008042370A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2452372C2 (ru) * | 2006-10-03 | 2012-06-10 | Дьюк Юниверсити | СИСТЕМЫ И СПОСОБЫ ОЦЕНКИ ПЕРЕНОСА ГАЗА В ЛЕГКИХ, ИСПОЛЬЗУЯ MPT С ГИПЕРПОЛЯРИЗОВАННЫМ 129Xe |
| US20100280358A1 (en) * | 2009-05-01 | 2010-11-04 | University Of Virginia Patent Foundation | Single breath-hold system and method for detection and assessment of multi-organ physiologic, morphologic and structural changes |
| JP2013006019A (ja) * | 2011-05-23 | 2013-01-10 | Toshiba Corp | 医用画像診断装置、画像処理装置及び超音波診断装置 |
| US10191126B2 (en) * | 2013-04-04 | 2019-01-29 | Regents Of The University Of Minnesota | Systems and methods for spatial gradient-based electrical property properties tomography using magnetic resonance imaging |
| US11428761B2 (en) | 2014-06-04 | 2022-08-30 | Koninklijke Philips N.V. | Patient proximity-modulated specific absorption rate |
| KR20190040929A (ko) * | 2016-01-11 | 2019-04-19 | 엘레멘탈 사이언티픽 레이저스 엘엘씨 | 샘플 처리중 동시적 패턴-스캔 배치 |
| JP6686733B2 (ja) * | 2016-06-23 | 2020-04-22 | コニカミノルタ株式会社 | 動態解析システム |
| RU2653994C1 (ru) * | 2017-05-12 | 2018-05-15 | Федеральное государственное бюджетное учреждение "Российский кардиологический научно-производственный комплекс" Министерства здравоохранения России (ФГБУ "РКНПК" МЗ РФ) | Способ количественной оценки объема нарушений перфузии легких |
| KR101949486B1 (ko) * | 2017-05-29 | 2019-02-18 | 성균관대학교산학협력단 | 자기 공명 영상 생성 방법 및 그 자기 공명 영상 장치 |
| KR101949491B1 (ko) * | 2017-05-29 | 2019-02-18 | 성균관대학교산학협력단 | 자기 공명 영상 생성 방법 및 그 자기 공명 영상 처리 장치 |
| US10677874B2 (en) * | 2018-02-20 | 2020-06-09 | Wisconsin Alumni Research Foundation | System and method for control of hyperpolarized gas-phase contamination in spectroscopic magnetic resonance imaging |
| US11944424B2 (en) * | 2018-05-18 | 2024-04-02 | Duke University | Dynamic 129Xe gas exchange spectroscopy |
| US11531851B2 (en) * | 2019-02-05 | 2022-12-20 | The Regents Of The University Of Michigan | Sequential minimal optimization algorithm for learning using partially available privileged information |
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| US4901019A (en) * | 1986-08-18 | 1990-02-13 | The General Hospital Corporation | Three-dimensional imaging |
| US4949042A (en) * | 1988-01-22 | 1990-08-14 | Kabushiki Kaisha Toshiba | Magnetic resonance imaging system |
| US5271401A (en) * | 1992-01-15 | 1993-12-21 | Praxair Technology, Inc. | Radiological imaging method |
| US5374890A (en) * | 1992-07-24 | 1994-12-20 | Picker International, Inc. | Simultaneous magnetic resonance imaging of multiple human organs |
| US5545396A (en) * | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
| US5809801A (en) * | 1996-03-29 | 1998-09-22 | The Trustees Of Princeton University | Cryogenic accumulator for spin-polarized xenon-129 |
| US5642625A (en) * | 1996-03-29 | 1997-07-01 | The Trustees Of Princeton University | High volume hyperpolarizer for spin-polarized noble gas |
| WO1997037239A1 (fr) * | 1996-03-29 | 1997-10-09 | Lawrence Berkeley National Laboratory | Amelioration de la rmn ou de l'irm par la presence de gaz nobles hyperpolarises |
| US6448769B1 (en) * | 1996-09-10 | 2002-09-10 | General Electric Company | Adiabatic pulse design |
| US6278893B1 (en) * | 1998-01-05 | 2001-08-21 | Nycomed Imaging As | Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent |
| AU756615B2 (en) * | 1998-03-18 | 2003-01-16 | Medi-Physics, Inc. | MR methods for imaging pulmonary and cardiac vasculature and evaluating blood flow using dissolved polarized 129Xe |
| EP1286171A3 (fr) * | 1998-03-18 | 2003-05-28 | Medi-Physics, Inc. | Evaluation de perfusion vasculaire par résonance magnétique avec 129Xe hyperpolarisé |
| US6211677B1 (en) * | 1998-05-08 | 2001-04-03 | Picker International, Inc. | Lung coil for imaging hyper-polarized gas in an MRI scanner |
| US6263228B1 (en) * | 1998-08-27 | 2001-07-17 | Toshiba America, Mri, Inc. | Method and apparatus for providing separate water-dominant and fat-dominant images from single scan single point dixon MRI sequences |
| CA2401308A1 (fr) * | 2000-03-13 | 2001-09-20 | Klaus D. Hagspiel | Procedures de diagnostic utilisant une injection directe de xe129 hyperpolarise, et produits et systemes associes |
| US6845262B2 (en) * | 2000-03-29 | 2005-01-18 | The Brigham And Women's Hospital, Inc. | Low-field MRI |
| US6775568B2 (en) * | 2000-04-12 | 2004-08-10 | University Of Virginia Patent Foundation | Exchange-based NMR imaging and spectroscopy of hyperpolarized xenon-129 |
| US6696040B2 (en) * | 2000-07-13 | 2004-02-24 | Medi-Physics, Inc. | Diagnostic procedures using 129Xe spectroscopy characteristic chemical shift to detect pathology in vivo |
| CA2419869A1 (fr) * | 2000-08-31 | 2002-03-07 | The University Of Akron | Milieux de detection de densites et nombres atomiques multiples avec multiplicateur d'electron de gaz pour des applications en imagerie |
| AU2002307309A1 (en) * | 2001-04-13 | 2002-10-28 | University Of Virginia Patent Foundation | Optimized high-speed magnetic resonance imaging method and system using hyperpolarized noble gases |
| US7179450B2 (en) * | 2001-09-20 | 2007-02-20 | Medi-Physics, Inc. | Methods for in vivo evaluation of pulmonary physiology and/or function using NMR signals of polarized Xe |
| CA2458901A1 (fr) * | 2001-09-20 | 2003-03-27 | Medi-Physics, Inc. | Procede d'evaluation in vivo d'etats physiologiques et/ou du fonctionnement d'organes ou de systemes, y-compris des procedes pour evaluer des troubles cardio-pulmonaires tels que l'insuffisance cardiaque par utilisation de 129xe polarise |
| DE60232734D1 (de) * | 2001-09-20 | 2009-08-06 | Medi Physics Inc | Verwendung von polarisiertem 129Xe zur Herstellung eines Medikaments zur Verwendung in einem in-vivo-NMR-Verfahren |
| US7099499B2 (en) * | 2002-08-15 | 2006-08-29 | General Electric Company | Fat/water separation and fat minimization magnetic resonance imaging systems and methods |
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| GB0308586D0 (en) * | 2003-04-14 | 2003-05-21 | Amersham Health R & D Ab | Method and arrangements in NMR spectroscopy |
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| US7596402B2 (en) * | 2003-05-05 | 2009-09-29 | Case Western Reserve University | MRI probe designs for minimally invasive intravascular tracking and imaging applications |
| RU2248011C1 (ru) | 2003-07-07 | 2005-03-10 | ГОУ ВПО Уральский государственный технический университет-УПИ | Световолоконный сцинтилляционный детектор рентгеновского излучения |
| WO2005055136A2 (fr) * | 2003-11-26 | 2005-06-16 | Board Of Regents, The University Of Texas System | Procede et dispositif pour irm a sensibilite de phase |
| WO2005086932A2 (fr) * | 2004-03-10 | 2005-09-22 | University Of Virginia Patent Foundation | Systeme de resonance magnetique nucleaire a echange pondere faisant intervenir du xenon 129 et procede associe |
| JP2006087763A (ja) * | 2004-09-27 | 2006-04-06 | Ge Medical Systems Global Technology Co Llc | データ収集方法およびｍｒｉ装置 |
| RU2452372C2 (ru) * | 2006-10-03 | 2012-06-10 | Дьюк Юниверсити | СИСТЕМЫ И СПОСОБЫ ОЦЕНКИ ПЕРЕНОСА ГАЗА В ЛЕГКИХ, ИСПОЛЬЗУЯ MPT С ГИПЕРПОЛЯРИЗОВАННЫМ 129Xe |
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2007
- 2007-10-02 RU RU2009116459/14A patent/RU2452372C2/ru not_active IP Right Cessation
- 2007-10-02 EP EP07839139A patent/EP2068709A4/fr not_active Ceased
- 2007-10-02 CA CA3152286A patent/CA3152286C/fr active Active
- 2007-10-02 AU AU2007305310A patent/AU2007305310B2/en not_active Expired - Fee Related
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- 2007-10-02 WO PCT/US2007/021155 patent/WO2008042370A1/fr active Application Filing
- 2007-10-02 NZ NZ575856A patent/NZ575856A/en not_active IP Right Cessation
- 2007-10-02 CA CA2666043A patent/CA2666043C/fr active Active
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- 2007-10-02 US US12/442,292 patent/US20100027864A1/en not_active Abandoned
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- 2007-10-02 JP JP2009531417A patent/JP2010505516A/ja active Pending
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2014
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2017
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2019
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Also Published As
| Publication number | Publication date |
|---|---|
| CA3065182C (fr) | 2022-05-17 |
| RU2009116459A (ru) | 2010-11-10 |
| US10895620B2 (en) | 2021-01-19 |
| US20190187231A1 (en) | 2019-06-20 |
| EP2068709A4 (fr) | 2010-03-31 |
| WO2008042370A1 (fr) | 2008-04-10 |
| US20080089846A1 (en) | 2008-04-17 |
| NZ575856A (en) | 2011-06-30 |
| US9625550B2 (en) | 2017-04-18 |
| CA2666043A1 (fr) | 2008-04-10 |
| CA3152286A1 (fr) | 2008-04-10 |
| EP2068709A1 (fr) | 2009-06-17 |
| US8911709B2 (en) | 2014-12-16 |
| RU2452372C2 (ru) | 2012-06-10 |
| CA3152286C (fr) | 2024-05-28 |
| CA3065182A1 (fr) | 2008-04-10 |
| US20150130459A1 (en) | 2015-05-14 |
| US20100027864A1 (en) | 2010-02-04 |
| KR20090086396A (ko) | 2009-08-12 |
| AU2007305310A1 (en) | 2008-04-10 |
| AU2007305310B2 (en) | 2013-01-17 |
| US20170176559A1 (en) | 2017-06-22 |
| CN101553168A (zh) | 2009-10-07 |
| US10261151B2 (en) | 2019-04-16 |
| BRPI0718198A2 (pt) | 2013-11-12 |
| JP2010505516A (ja) | 2010-02-25 |
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