CA2660362C - Use of a device or spray apparatus for oral administration of a liquid containing an active substance for improved absorption - Google Patents

Use of a device or spray apparatus for oral administration of a liquid containing an active substance for improved absorption Download PDF

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Publication number
CA2660362C
CA2660362C CA2660362A CA2660362A CA2660362C CA 2660362 C CA2660362 C CA 2660362C CA 2660362 A CA2660362 A CA 2660362A CA 2660362 A CA2660362 A CA 2660362A CA 2660362 C CA2660362 C CA 2660362C
Authority
CA
Canada
Prior art keywords
nicotine
liquid
subject
mouth
alkaloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2660362A
Other languages
English (en)
French (fr)
Other versions
CA2660362A1 (en
Inventor
Anders Axelsson
Karl Olov Fagerstroem
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Modoral Brands Inc
Original Assignee
Niconovum USA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Niconovum USA Inc filed Critical Niconovum USA Inc
Publication of CA2660362A1 publication Critical patent/CA2660362A1/en
Application granted granted Critical
Publication of CA2660362C publication Critical patent/CA2660362C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CA2660362A 2006-09-27 2007-09-27 Use of a device or spray apparatus for oral administration of a liquid containing an active substance for improved absorption Active CA2660362C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200601246 2006-09-27
DKPA200601246 2006-09-27
US95161907P 2007-07-24 2007-07-24
US60/951,619 2007-07-24
PCT/EP2007/008420 WO2008037470A1 (en) 2006-09-27 2007-09-27 Directional use

Publications (2)

Publication Number Publication Date
CA2660362A1 CA2660362A1 (en) 2008-04-03
CA2660362C true CA2660362C (en) 2018-03-20

Family

ID=38776389

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2660362A Active CA2660362C (en) 2006-09-27 2007-09-27 Use of a device or spray apparatus for oral administration of a liquid containing an active substance for improved absorption

Country Status (13)

Country Link
US (1) US10092715B2 (https=)
EP (1) EP2068982A1 (https=)
JP (2) JP2010504931A (https=)
KR (1) KR20090055606A (https=)
CN (1) CN101516426A (https=)
AU (1) AU2007302256A1 (https=)
BR (1) BRPI0716995A2 (https=)
CA (1) CA2660362C (https=)
IL (1) IL197573A0 (https=)
MX (1) MX2009001865A (https=)
NO (1) NO20091345L (https=)
RU (1) RU2009115720A (https=)
WO (1) WO2008037470A1 (https=)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT507187B1 (de) * 2008-10-23 2010-03-15 Helmut Dr Buchberger Inhalator
CA2750815C (en) * 2009-02-09 2018-03-13 Swetree Technologies Ab Polymer shells
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
CA2824970C (en) 2011-02-11 2016-05-03 Batmark Limited Inhaler component
AT510837B1 (de) 2011-07-27 2012-07-15 Helmut Dr Buchberger Inhalatorkomponente
PL2753202T3 (pl) 2011-09-06 2016-11-30 Podgrzewanie materiału przeznaczonego do palenia
EP3892125A3 (en) 2011-09-06 2022-01-05 Nicoventures Trading Limited Heating smokable material
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
AT511344B1 (de) 2011-10-21 2012-11-15 Helmut Dr Buchberger Inhalatorkomponente
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
GB201207039D0 (en) 2012-04-23 2012-06-06 British American Tobacco Co Heating smokeable material
GB2504075A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
GB2504076A (en) 2012-07-16 2014-01-22 Nicoventures Holdings Ltd Electronic smoking device
USD701599S1 (en) * 2013-03-26 2014-03-25 Pediatric Innovations USA, LLC Nasal device
USD732658S1 (en) 2013-03-26 2015-06-23 Pediatric Innovations USA, LLC Nasal device with airplane wings
USD732659S1 (en) 2013-03-26 2015-06-23 Pediatric Innovations USA, LLC Car-shaped nasal device
USD701956S1 (en) * 2013-03-26 2014-04-01 Pediatric Innovations USA, LLC Nasal device
GB2513639A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2513637A (en) 2013-05-02 2014-11-05 Nicoventures Holdings Ltd Electronic cigarette
GB2514893B (en) 2013-06-04 2017-12-06 Nicoventures Holdings Ltd Container
GB201407426D0 (en) 2014-04-28 2014-06-11 Batmark Ltd Aerosol forming component
GB2528673B (en) 2014-07-25 2020-07-01 Nicoventures Holdings Ltd Aerosol provision system
GB2533135B (en) 2014-12-11 2020-11-11 Nicoventures Holdings Ltd Aerosol provision systems
GB201505595D0 (en) 2015-03-31 2015-05-13 British American Tobacco Co Cartridge for use with apparatus for heating smokeable material
GB201505597D0 (en) 2015-03-31 2015-05-13 British American Tobacco Co Article for use with apparatus for heating smokable material
GB201511361D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic vapour provision system
GB201511349D0 (en) 2015-06-29 2015-08-12 Nicoventures Holdings Ltd Electronic aerosol provision systems
US20170055584A1 (en) 2015-08-31 2017-03-02 British American Tobacco (Investments) Limited Article for use with apparatus for heating smokable material
US11924930B2 (en) 2015-08-31 2024-03-05 Nicoventures Trading Limited Article for use with apparatus for heating smokable material
GB201516729D0 (en) * 2015-09-22 2015-11-04 The Technology Partnership Plc Liquid nicotine formulation
GB2542838B (en) 2015-10-01 2022-01-12 Nicoventures Trading Ltd Aerosol provision system
US20170119046A1 (en) 2015-10-30 2017-05-04 British American Tobacco (Investments) Limited Apparatus for Heating Smokable Material
US10532046B2 (en) 2015-12-03 2020-01-14 Niconovum Usa, Inc. Multi-phase delivery compositions and products incorporating such compositions
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US11744964B2 (en) 2016-04-27 2023-09-05 Nicoventures Trading Limited Electronic aerosol provision system and vaporizer therefor
WO2018113916A1 (en) * 2016-12-20 2018-06-28 Fertin Pharma A/S A mucoadhesive oromucosal formulation comprising a nicotine complex
CA3085065C (en) 2017-12-08 2023-12-05 Fertin Pharma A/S Formulations providing high nicotine concentrations
CA3085064C (en) * 2017-12-08 2023-10-24 Fertin Pharma A/S Nicotine mouth spray
WO2019110072A1 (en) 2017-12-08 2019-06-13 Fertin Pharma A/S Nicotine tablet
CN112384504A (zh) 2018-06-15 2021-02-19 R.J.雷诺兹烟草公司 烟碱的纯化
JP6676805B2 (ja) * 2018-07-12 2020-04-08 株式会社 東亜産業 芳香カートリッジ用充填物、それを有する芳香カートリッジ用エアロゾル形成基材およびそれを有する芳香カートリッジ
JP7528084B2 (ja) * 2018-12-28 2024-08-05 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 金属塩を含むニコチン製剤
WO2020235112A1 (ja) 2019-05-21 2020-11-26 株式会社 東亜産業 被加熱芳香発生体及び芳香カートリッジ、並びに、被加熱芳香発生体の製造方法及び製造装置
US12213510B2 (en) 2019-09-11 2025-02-04 Nicoventures Trading Limited Pouched products with enhanced flavor stability
US12342847B2 (en) 2019-09-11 2025-07-01 Nicoventures Trading Limited Oral product with cellulosic flavor stabilizer
CN110558605B (zh) * 2019-09-27 2021-07-06 深圳雾芯科技有限公司 电子烟液
US12433321B2 (en) 2019-12-09 2025-10-07 Nicoventures Trading Limited Oral composition with beet material
US12439952B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Moist oral compositions
US12599160B2 (en) 2019-12-09 2026-04-14 Nicoventures Trading Limited Lipid-containing oral composition
US12137723B2 (en) 2019-12-09 2024-11-12 Nicoventures Trading Limited Oral products with active ingredient combinations
US12310959B2 (en) 2019-12-09 2025-05-27 Nicoventures Trading Limited Oral compositions with reduced water content
US12439949B2 (en) 2019-12-09 2025-10-14 Nicoventures Trading Limited Oral compositions with reduced water activity
US12520867B2 (en) 2019-12-09 2026-01-13 Nicoventures Trading Limited Buffered oral compositions
US12171872B2 (en) 2019-12-09 2024-12-24 Nicoventures Trading Limited Oral compositions and methods of manufacture
US11672862B2 (en) 2019-12-09 2023-06-13 Nicoventures Trading Limited Oral products with reduced irritation
EP4072338A1 (en) 2019-12-09 2022-10-19 Nicoventures Trading Limited Agents for oral composition
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US12151023B2 (en) 2019-12-09 2024-11-26 Nicoventures Trading Limited Oral composition with beet material
US12550928B2 (en) 2019-12-09 2026-02-17 Nicoventures Trading Limited Liquid oral composition
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
US12491250B2 (en) 2019-12-09 2025-12-09 Nicoventures Trading Limited Oral composition with nanocrystalline cellulose
US11889856B2 (en) 2019-12-09 2024-02-06 Nicoventures Trading Limited Oral foam composition
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
US11883527B2 (en) 2019-12-09 2024-01-30 Nicoventures Trading Limited Oral composition and method of manufacture
US11969502B2 (en) 2019-12-09 2024-04-30 Nicoventures Trading Limited Oral products
JP2023504756A (ja) 2019-12-09 2023-02-06 ニコベンチャーズ トレーディング リミテッド カンナビノイドを含む口腔用製品
CA3181912A1 (en) 2020-06-08 2021-12-16 Anthony Richard Gerardi Effervescent oral composition comprising an active ingredient
US11839602B2 (en) 2020-11-25 2023-12-12 Nicoventures Trading Limited Oral cannabinoid product with lipid component
WO2022261552A1 (en) * 2021-06-11 2022-12-15 Boa Nutrition, Inc. Nozzle with fan for delivering aerosols
MX2023015529A (es) 2021-06-25 2024-03-05 Nicoventures Trading Ltd Productos orales y metodo de fabricacion.
JP2024530905A (ja) 2021-07-30 2024-08-27 ニコベンチャーズ トレーディング リミテッド 微結晶性セルロースを含むエアロゾル生成基材
CA3233375A1 (en) 2021-09-30 2023-04-06 Michael Zawadzki Oral product with a basic amine and an ion pairing agent

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2619718B1 (fr) * 1987-09-02 1991-07-12 Medibrevex Nouvelles formes galeniques de beta-2-mimetiques pour administration par voie per- et sublinguale
GB8828468D0 (en) 1988-12-06 1989-01-05 Stoppers Co Ltd Nicotine containing lozenge
US5326570A (en) * 1991-07-23 1994-07-05 Pharmavene, Inc. Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
US5362496A (en) 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
IT233948Y1 (it) 1994-07-20 2000-02-16 Plastiape Spa Dispositivo erogatore tascabile,particolrmente studiato per immettere nel cavo orale sostanze medicamentose nebulizzate
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
FI974578L (fi) * 1997-12-19 1999-06-20 Orion Yhtymae Oyj Menetelmä levosimendaanin antamiseksi
US5981499A (en) 1998-02-20 1999-11-09 Atlantic Biomed Corporation Lesion-directed antibiotics in dry dosage forms for the treatment of shallow ulcers of the oral mucosa
US6080783A (en) * 1998-09-01 2000-06-27 Gum Tech International, Inc. Method and composition for delivering zinc to the nasal membrane
CN1354624A (zh) 1998-12-15 2002-06-19 Wm·雷格利Jr·公司 从口香糖中控制释放活性剂
US6799576B2 (en) * 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
NZ521034A (en) * 2000-02-28 2004-08-27 Vectura Ltd Improvements in or relating to the delivery of oral drugs
SE0003665D0 (sv) * 2000-10-11 2000-10-11 Astrazeneca Ab A delivery device
DK1361864T3 (en) * 2001-02-14 2014-03-03 Gw Pharma Ltd FLYLDENDE SPRAY FORMULATIONS FOR buccal administration of cannabinoids
SE521512C2 (sv) * 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
US20040037879A1 (en) 2001-11-02 2004-02-26 Adusumilli Prasad S. Oral controlled release forms useful for reducing or preventing nicotine cravings
SE0104388D0 (sv) 2001-12-27 2001-12-27 Pharmacia Ab New formulation and use and manufacture thereof
PT1578422E (pt) * 2002-12-20 2007-06-14 Niconovum Ab Material particulado contendo nicotina fisicamente e quimicamente estável
EP1617823B1 (en) * 2003-01-24 2019-01-09 Nicachet AB A pouch comprising a nicotine composition for transmucosal delivery
GB0305581D0 (en) 2003-03-11 2003-04-16 Dallas Burston Ltd Dispensing devices
US20050150489A1 (en) * 2004-01-12 2005-07-14 Steve Dunfield Dispensing medicaments based on rates of medicament action
JP2007533697A (ja) * 2004-04-22 2007-11-22 デュオコート エービー グルココルチコイド救急治療用の医薬組成物
EP1893953A2 (en) * 2005-05-18 2008-03-05 The GI Company, Inc Oral drug delivery system and methods of use thereof

Also Published As

Publication number Publication date
CN101516426A (zh) 2009-08-26
JP2010504931A (ja) 2010-02-18
MX2009001865A (es) 2009-04-07
KR20090055606A (ko) 2009-06-02
AU2007302256A1 (en) 2008-04-03
CA2660362A1 (en) 2008-04-03
NO20091345L (no) 2009-04-01
WO2008037470A1 (en) 2008-04-03
US10092715B2 (en) 2018-10-09
RU2009115720A (ru) 2010-11-10
EP2068982A1 (en) 2009-06-17
US20100108059A1 (en) 2010-05-06
IL197573A0 (en) 2009-12-24
BRPI0716995A2 (pt) 2013-10-15
JP2014076370A (ja) 2014-05-01

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