CA2657349A1 - Human growth and differentiation factor gdf-5 - Google Patents
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- CA2657349A1 CA2657349A1 CA002657349A CA2657349A CA2657349A1 CA 2657349 A1 CA2657349 A1 CA 2657349A1 CA 002657349 A CA002657349 A CA 002657349A CA 2657349 A CA2657349 A CA 2657349A CA 2657349 A1 CA2657349 A1 CA 2657349A1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06014928.3 | 2006-07-18 | ||
| EP06014928A EP1880731A1 (en) | 2006-07-18 | 2006-07-18 | Human growth and differentiation factor GDF-5 |
| PCT/EP2007/006331 WO2008009419A1 (en) | 2006-07-18 | 2007-07-17 | Human growth and differentiation factor gdf-5 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2657349A1 true CA2657349A1 (en) | 2008-01-24 |
Family
ID=37663742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002657349A Abandoned CA2657349A1 (en) | 2006-07-18 | 2007-07-17 | Human growth and differentiation factor gdf-5 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8361745B2 (enExample) |
| EP (2) | EP1880731A1 (enExample) |
| JP (1) | JP2009543566A (enExample) |
| CA (1) | CA2657349A1 (enExample) |
| WO (1) | WO2008009419A1 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2007234612B2 (en) | 2006-12-14 | 2013-06-27 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein stabilization formulations |
| EP2121142B1 (en) * | 2007-01-25 | 2013-04-03 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH | Use of gdf-5 for the improvement or maintenance of dermal appearance |
| US7678764B2 (en) | 2007-06-29 | 2010-03-16 | Johnson & Johnson Regenerative Therapeutics, Llc | Protein formulations for use at elevated temperatures |
| JP5323832B2 (ja) | 2007-08-07 | 2013-10-23 | アドバンスト・テクノロジーズ・アンド・リジェネレイティブ・メディスン・エルエルシー | 酸性水溶液中にｇｄｆ−５を含むタンパク質製剤 |
| BRPI0911048A2 (pt) | 2008-04-14 | 2015-12-29 | Atrm Llc | formulações líquidas tamponadas de gdf-5 |
| WO2009152085A1 (en) * | 2008-06-09 | 2009-12-17 | Wyeth | Novel bmp-12-related proteins and methods of their manufacture |
| EP2537538A1 (en) * | 2011-06-22 | 2012-12-26 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH | Bioresorbable Wound Dressing |
| US9051389B2 (en) | 2013-01-25 | 2015-06-09 | Warsaw Orthopedic, Inc. | Expression conditions and methods of human recombinant growth and differentiation factor-5 (rhGDF-5) |
| US9359417B2 (en) | 2013-01-25 | 2016-06-07 | Warsaw Orthopedic, Inc. | Cell cultures and methods of human recombinant growth and differentiaton factor-5 (rhGDF-5) |
| US9169308B2 (en) | 2013-01-25 | 2015-10-27 | Warsaw Orthopedic, Inc. | Methods and compositions of human recombinant growth and differentiation factor-5 (rhGDF-5) isolated from inclusion bodies |
| US8945872B2 (en) | 2013-01-25 | 2015-02-03 | Warsaw Orthopedic, Inc. | Methods of purifying human recombinant growth and differentiation factor-5 (rhGDF-5) protein |
| US8956829B2 (en) | 2013-01-25 | 2015-02-17 | Warsaw Orthopedic, Inc. | Human recombinant growth and differentiaton factor-5 (rhGDF-5) |
| JP2016183118A (ja) * | 2015-03-25 | 2016-10-20 | 東ソー株式会社 | 増殖因子前駆体のリフォールディング方法 |
| US11324806B2 (en) | 2018-10-19 | 2022-05-10 | Warsaw Orthopedic, Inc. | Sustained delivery of a growth differentiation factor |
| EP3723212B1 (en) | 2019-04-11 | 2024-05-29 | Aptiv Technologies Limited | Network connector module for a network connector |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5935815A (en) * | 1989-10-25 | 1999-08-10 | Katholieke Universiteit Leuven | Process for micro biological production of proteins |
| DE19525416A1 (de) * | 1995-07-12 | 1997-01-16 | Bioph Biotech Entw Pharm Gmbh | Verwendung von MP52 zur Behandlung und Prävention von Erkrankungen des Nervensystems |
| EP1439190A1 (en) * | 1993-01-12 | 2004-07-21 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-5 |
| DE69403439T2 (de) * | 1993-01-12 | 1997-10-23 | Genentech Inc | Tgf-beta zusammensetzung zum herbeiführen von knochenwachstum |
| PT955313E (pt) * | 1995-04-19 | 2006-07-31 | Bioph Biotech Entw Pharm Gmbh | Nova proteina e processo para a sua producao |
| DE19647853A1 (de) | 1996-11-19 | 1998-05-20 | Bioph Biotech Entw Pharm Gmbh | Verbindungen mit verbesserter knorpel- und/oder knocheninduzierender Aktivität |
| EP1074620A1 (en) * | 1999-08-06 | 2001-02-07 | HyGene AG | Monomeric protein of the TGF-beta family |
| US6344541B1 (en) * | 1998-09-25 | 2002-02-05 | Amgen Inc. | DKR polypeptides |
| CA2441588A1 (en) * | 2001-03-23 | 2002-10-03 | Biopharm Gesellschaft Zue Biotechnologischen Entwicklung Von Pharmaka Mbh | Use of cytokines of the tgf-.beta. superfamily for the treatment and diagnosis of skin related disorders |
| CA2484556A1 (en) * | 2001-12-21 | 2003-07-24 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| BR0314270A (pt) * | 2002-09-16 | 2005-08-02 | Univ Johns Hopkins | Ativação de miostatina com metaloprotease e processos de modulação da atividade da miostatina |
| EP1462126A1 (en) * | 2003-03-28 | 2004-09-29 | BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH | Improved Osteoinductive Materials |
| JP2007222003A (ja) | 2004-03-29 | 2007-09-06 | Matsushita Electric Ind Co Ltd | 放線菌Ｈ＋−ｐｙｒｏｐｈｏｓｐｈａｔａｓｅ合成遺伝子の作成と大腸菌での発現システム |
-
2006
- 2006-07-18 EP EP06014928A patent/EP1880731A1/en not_active Withdrawn
-
2007
- 2007-07-17 CA CA002657349A patent/CA2657349A1/en not_active Abandoned
- 2007-07-17 WO PCT/EP2007/006331 patent/WO2008009419A1/en not_active Ceased
- 2007-07-17 US US12/374,080 patent/US8361745B2/en not_active Expired - Fee Related
- 2007-07-17 EP EP07786127.6A patent/EP2043674B1/en not_active Not-in-force
- 2007-07-17 JP JP2009519863A patent/JP2009543566A/ja active Pending
-
2012
- 2012-12-20 US US13/721,513 patent/US8871710B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8871710B2 (en) | 2014-10-28 |
| WO2008009419A1 (en) | 2008-01-24 |
| JP2009543566A (ja) | 2009-12-10 |
| US20130309221A1 (en) | 2013-11-21 |
| EP2043674A1 (en) | 2009-04-08 |
| EP2043674B1 (en) | 2014-05-07 |
| US20100129342A1 (en) | 2010-05-27 |
| EP1880731A1 (en) | 2008-01-23 |
| US8361745B2 (en) | 2013-01-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20200204 |