CA2656485A1 - Method, composition and device for sampling natriuretic peptides in a biological fluid - Google Patents

Method, composition and device for sampling natriuretic peptides in a biological fluid Download PDF

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Publication number
CA2656485A1
CA2656485A1 CA002656485A CA2656485A CA2656485A1 CA 2656485 A1 CA2656485 A1 CA 2656485A1 CA 002656485 A CA002656485 A CA 002656485A CA 2656485 A CA2656485 A CA 2656485A CA 2656485 A1 CA2656485 A1 CA 2656485A1
Authority
CA
Canada
Prior art keywords
protease inhibitor
bnp
fluid
biological fluid
effective amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002656485A
Other languages
English (en)
French (fr)
Inventor
Ute Schellenberger
Eric E. Niederkofler
Urban A. Kiernan
Jessica O'rear
Randall W. Nelson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Crimson International Assets LLC
Original Assignee
Scios LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios LLC filed Critical Scios LLC
Publication of CA2656485A1 publication Critical patent/CA2656485A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
CA002656485A 2008-02-27 2009-02-27 Method, composition and device for sampling natriuretic peptides in a biological fluid Abandoned CA2656485A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12/038,355 US9482677B2 (en) 2008-02-27 2008-02-27 Method, composition and device for sampling natriuretic peptides in a biological fluid
US12/038,355 2008-02-27

Publications (1)

Publication Number Publication Date
CA2656485A1 true CA2656485A1 (en) 2009-08-27

Family

ID=40671134

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002656485A Abandoned CA2656485A1 (en) 2008-02-27 2009-02-27 Method, composition and device for sampling natriuretic peptides in a biological fluid

Country Status (4)

Country Link
US (3) US9482677B2 (https=)
EP (1) EP2098866B1 (https=)
JP (1) JP5734547B2 (https=)
CA (1) CA2656485A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9482677B2 (en) 2008-02-27 2016-11-01 Scios Inc. Method, composition and device for sampling natriuretic peptides in a biological fluid
AU2010309808B2 (en) * 2009-10-21 2016-04-28 Mycartis Nv Biomarker for diagnosis, prediction and/or prognosis of acute heart failure and uses thereof
JP6491880B2 (ja) * 2011-08-23 2019-03-27 シナプス・ビー．ブイ．Ｓｙｎａｐｓｅ Ｂ．Ｖ． 異物表面との接触による血液凝固系の活性化の熱安定性阻害剤
CN103781904A (zh) * 2011-09-13 2014-05-07 奥林巴斯株式会社 含有胰液成分的生物试样中的蛋白酶的抑制方法
WO2013190867A1 (ja) 2012-06-22 2013-12-27 オリンパス株式会社 膵液成分含有試料の調製方法、及び膵液成分を含有する生体試料の室温保存用キット
US20140273008A1 (en) * 2013-03-15 2014-09-18 Molecular Bioproducts, Inc. Methods to assess enzyme activity using mass spectrometric immunoassay
ES2938089T3 (es) 2015-08-13 2023-04-04 Takeda Pharmaceuticals Co Tubos de extracción de sangre al vacío que contienen inhibidores de proteasa para la evaluación de la activación del sistema de contacto

Family Cites Families (27)

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Publication number Priority date Publication date Assignee Title
US3092465A (en) 1960-03-25 1963-06-04 Miles Lab Diagnostic test device for blood sugar
DE1598153C3 (de) 1966-11-22 1973-11-22 Boehringer Mannheim Gmbh, 6800 Mannheim Diagnostisches Mittel zum Nach weis der Inhaltsstoffe von Korperflus sigkeiten
US3783672A (en) * 1972-02-23 1974-01-08 A Morgolenko High-speed machines for shaping metals which employ the energy of high-pressure gas
DE3029579C2 (de) 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
US4816224A (en) 1980-08-05 1989-03-28 Boehringer Mannheim Gmbh Device for separating plasma or serum from whole blood and analyzing the same
US5135719A (en) 1986-10-29 1992-08-04 Biotrack, Inc. Blood separation device comprising a filter and a capillary flow pathway exiting the filter
US4820737A (en) 1987-02-17 1989-04-11 University Of Iowa Research Foundation Lacrimal secretion stimulant (lss)
CA1339210C (en) * 1988-05-31 1997-08-05 John Lewicki Recombinant techniques for production of novel natriuretic and vasodilator peptides
GB9211686D0 (en) * 1992-06-03 1992-07-15 Medisinsk Innovation A S Chemical compounds
WO1996037777A1 (en) * 1995-05-23 1996-11-28 Nelson Randall W Mass spectrometric immunoassay
CA2248140C (en) * 1996-03-04 2005-02-01 Ronald P. Mischak Assay and reagents for quantifying hbnp
DE19628236A1 (de) 1996-07-12 1998-01-15 Boehringer Mannheim Gmbh Reagenz zur Erhöhung der Serinproteasen-Inhibitionsspezifität
US6102872A (en) * 1997-11-03 2000-08-15 Pacific Biometrics, Inc. Glucose detector and method
ATE365550T1 (de) 1998-03-13 2007-07-15 Univ Johns Hopkins Med Verwendung von einem protein kinase hemmer wie z.b. genistein bei der behandlung von diabetischer retinopathie
US6806075B1 (en) * 1998-06-05 2004-10-19 Schering Ag Corin, a serine protease
GB9827348D0 (en) 1998-12-12 1999-02-03 Univ Leicester Natriuretic peptide
US6407211B1 (en) 1999-12-17 2002-06-18 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides
CA2434699A1 (en) 2001-01-17 2002-10-17 Randall W. Nelson An integrated high throughput system for the analysis of biomolecules
AU2003234382B2 (en) 2002-05-13 2010-07-08 Becton, Dickinson And Company Protease inhibitor sample collection system
CA2430889A1 (en) 2002-06-19 2003-12-19 Bayer Corporation Stabilization of brain natriuretic peptide (bnp) in blood samples, methods and compositions related thereto
WO2004094460A2 (en) * 2003-04-17 2004-11-04 Ciphergen Biosystems, Inc. Polypeptides related to natriuretic peptides and methods of their identification and use
EP1625164B1 (en) * 2003-05-12 2011-07-20 Roche Diagnostics GmbH Method of detecting probnp with a monoclonal antibody binding to the amino acids 42-46
US7083163B2 (en) * 2003-09-19 2006-08-01 Tenneco Automotive Operating Company Inc. Booster with spring to adapt air spring pressure for load dependent shock absorber
DE10355731A1 (de) * 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP
US20060183681A1 (en) * 2005-02-14 2006-08-17 Bio-Rad Laboratories, Inc. Stabilized compositions containing natriuretic peptides
WO2007041645A2 (en) 2005-10-03 2007-04-12 Scios Inc. Oxidized human bnp
US9482677B2 (en) 2008-02-27 2016-11-01 Scios Inc. Method, composition and device for sampling natriuretic peptides in a biological fluid

Also Published As

Publication number Publication date
US20090215182A1 (en) 2009-08-27
US20200158739A1 (en) 2020-05-21
EP2098866B1 (en) 2013-05-01
US11105819B2 (en) 2021-08-31
US10641781B2 (en) 2020-05-05
US9482677B2 (en) 2016-11-01
JP5734547B2 (ja) 2015-06-17
EP2098866A1 (en) 2009-09-09
US20170003305A1 (en) 2017-01-05
JP2009204612A (ja) 2009-09-10

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140226

FZDE Discontinued

Effective date: 20210831