CA2654784A1 - Acides phenylacetiques substitues utilises en tant qu'antagonistes de dp-2 - Google Patents

Acides phenylacetiques substitues utilises en tant qu'antagonistes de dp-2 Download PDF

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Publication number
CA2654784A1
CA2654784A1 CA002654784A CA2654784A CA2654784A1 CA 2654784 A1 CA2654784 A1 CA 2654784A1 CA 002654784 A CA002654784 A CA 002654784A CA 2654784 A CA2654784 A CA 2654784A CA 2654784 A1 CA2654784 A1 CA 2654784A1
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Canada
Prior art keywords
phenyl
acetic acid
piperazin
ylmethyl
benzyloxy
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Abandoned
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CA002654784A
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English (en)
Inventor
Thomas Dudler
Francine Farouz
Kerry Fowler
Nataly Hawthorn
Danwen Huang
Angela Judkins
Musong Kim
Joshua Odingo
Amy Oliver
Mark Reed
Fuqiang Ruan
Eugene Thorsett
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Icos Corp
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Individual
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Publication of CA2654784A1 publication Critical patent/CA2654784A1/fr
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    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
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CA002654784A 2006-06-09 2007-06-08 Acides phenylacetiques substitues utilises en tant qu'antagonistes de dp-2 Abandoned CA2654784A1 (fr)

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UA96459C2 (uk) 2006-08-21 2011-11-10 Еррей Біофарма Інк. 4-заміщені похідні феноксифенілоцтової кислоти
AU2008312653B2 (en) * 2007-10-19 2013-03-07 Janssen Pharmaceutica, N.V. Amide linked modulators of y-secretase
JP5543354B2 (ja) * 2007-10-19 2014-07-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ γ−セクレターゼのアミン結合調節物質
EP2215043B1 (fr) * 2007-10-19 2013-03-06 Janssen Pharmaceutica, N.V. Modulateurs liés au carbone de la -sécrétase
WO2011153359A1 (fr) 2010-06-04 2011-12-08 Albany Molecular Research, Inc. Inhibiteurs du transporteur 1 de la glycine, procédés de fabrication associés, et utilisations associées
CA2805452C (fr) 2010-07-05 2018-07-31 Actelion Pharmaceuticals Ltd Derives d'heterocyclyle substitues par un 1-phenyle et leur utilisation en tant que modulateurs des recepteurs de la prostaglandine d2
EP2457900A1 (fr) 2010-11-25 2012-05-30 Almirall, S.A. Nouveaux dérivés de pyrazole présentant un comportement antagoniste CRTH2
EP2744807A4 (fr) 2011-08-15 2015-03-04 Intermune Inc Antagonistes des récepteurs d'acide lysophosphatidique
CN104011021B (zh) 2011-12-21 2016-08-24 埃科特莱茵药品有限公司 杂环衍生物及其作为前列腺素d2受体调节剂的用途
WO2014006585A1 (fr) 2012-07-05 2014-01-09 Actelion Pharmaceuticals Ltd Dérivés hétérocyclylés 1-phényl-substitués et leur utilisation en tant que modulateurs du récepteur de la prostaglandine d2
CN102757339A (zh) * 2012-08-01 2012-10-31 北京联本医药化学技术有限公司 一种改进的4-(2-羧基苄氧基)苯乙酸制备方法
CN105579439B (zh) 2013-05-07 2018-10-19 加州大学评议会 辐射减轻性药物制剂
CN112300120B (zh) * 2019-07-31 2023-04-14 北京四环制药有限公司 一种用于制备巴罗萨韦或其衍生物的化合物及其制备方法和其应用
JP2023503926A (ja) * 2019-11-22 2023-02-01 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア Ｔａｓｐａｓｅ１阻害剤およびその使用

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DE60303238T2 (de) * 2003-04-25 2006-09-14 Actimis Pharmaceuticals, Inc., La Jolla Pyrimidin-Essigsäure Derivate geeignet zur Behandlung von CRTH2-bedingten Krankheiten
SE0302811D0 (sv) * 2003-10-23 2003-10-23 Astrazeneca Ab Novel compounds
AR048523A1 (es) * 2004-04-07 2006-05-03 Kalypsys Inc Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos
US20090118318A1 (en) * 2005-04-04 2009-05-07 Stephen Connolly Novel Diazaspiroalkanes and Their Use for Treatment of CCR8 Mediated Diseases
CA2621164A1 (fr) * 2005-08-26 2007-03-01 Shionogi & Co., Ltd. Derive ayant une activite agoniste vis-a-vis du ppar
JPWO2007034882A1 (ja) * 2005-09-22 2009-03-26 大日本住友製薬株式会社 新規アデニン化合物

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NO20090138L (no) 2009-03-05
WO2007143745A2 (fr) 2007-12-13
MX2008015696A (es) 2009-02-10
EP2044044A2 (fr) 2009-04-08
BRPI0712301A2 (pt) 2012-01-17
AU2007256597A1 (en) 2007-12-13
WO2007143745A3 (fr) 2008-04-17
EA200802415A1 (ru) 2009-06-30
JP2009539880A (ja) 2009-11-19
CN101490024A (zh) 2009-07-22

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