MX2008015696A - Acidos fenil aceticos sustituidos como antagonistas de dp-2. - Google Patents

Acidos fenil aceticos sustituidos como antagonistas de dp-2.

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Publication number
MX2008015696A
MX2008015696A MX2008015696A MX2008015696A MX2008015696A MX 2008015696 A MX2008015696 A MX 2008015696A MX 2008015696 A MX2008015696 A MX 2008015696A MX 2008015696 A MX2008015696 A MX 2008015696A MX 2008015696 A MX2008015696 A MX 2008015696A
Authority
MX
Mexico
Prior art keywords
phenyl
acid
piperazin
acetic
ylmethyl
Prior art date
Application number
MX2008015696A
Other languages
English (en)
Spanish (es)
Inventor
Kerry Fowler
Joshua Odingo
Amy Oliver
Thomas Dudler
Francine Farouz
Nataly Hawthorn
Danwen Huang
Musong Kim
Mark Reed
Fuqiang Ruan
Eugene Thorsett
Angela Judkins
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Publication of MX2008015696A publication Critical patent/MX2008015696A/es

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    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
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MX2008015696A 2006-06-09 2007-06-08 Acidos fenil aceticos sustituidos como antagonistas de dp-2. MX2008015696A (es)

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PCT/US2007/070803 WO2007143745A2 (fr) 2006-06-09 2007-06-08 Acides phénylacétiques substitués utilisés en tant qu'antagonistes de dp-2

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UA96459C2 (uk) 2006-08-21 2011-11-10 Еррей Біофарма Інк. 4-заміщені похідні феноксифенілоцтової кислоти
AU2008312653B2 (en) * 2007-10-19 2013-03-07 Janssen Pharmaceutica, N.V. Amide linked modulators of y-secretase
JP5543354B2 (ja) * 2007-10-19 2014-07-09 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ γ−セクレターゼのアミン結合調節物質
EP2215043B1 (fr) * 2007-10-19 2013-03-06 Janssen Pharmaceutica, N.V. Modulateurs liés au carbone de la -sécrétase
WO2011153359A1 (fr) 2010-06-04 2011-12-08 Albany Molecular Research, Inc. Inhibiteurs du transporteur 1 de la glycine, procédés de fabrication associés, et utilisations associées
CA2805452C (fr) 2010-07-05 2018-07-31 Actelion Pharmaceuticals Ltd Derives d'heterocyclyle substitues par un 1-phenyle et leur utilisation en tant que modulateurs des recepteurs de la prostaglandine d2
EP2457900A1 (fr) 2010-11-25 2012-05-30 Almirall, S.A. Nouveaux dérivés de pyrazole présentant un comportement antagoniste CRTH2
EP2744807A4 (fr) 2011-08-15 2015-03-04 Intermune Inc Antagonistes des récepteurs d'acide lysophosphatidique
CN104011021B (zh) 2011-12-21 2016-08-24 埃科特莱茵药品有限公司 杂环衍生物及其作为前列腺素d2受体调节剂的用途
WO2014006585A1 (fr) 2012-07-05 2014-01-09 Actelion Pharmaceuticals Ltd Dérivés hétérocyclylés 1-phényl-substitués et leur utilisation en tant que modulateurs du récepteur de la prostaglandine d2
CN102757339A (zh) * 2012-08-01 2012-10-31 北京联本医药化学技术有限公司 一种改进的4-(2-羧基苄氧基)苯乙酸制备方法
CN105579439B (zh) 2013-05-07 2018-10-19 加州大学评议会 辐射减轻性药物制剂
CN112300120B (zh) * 2019-07-31 2023-04-14 北京四环制药有限公司 一种用于制备巴罗萨韦或其衍生物的化合物及其制备方法和其应用
JP2023503926A (ja) * 2019-11-22 2023-02-01 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア Ｔａｓｐａｓｅ１阻害剤およびその使用

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SE0302811D0 (sv) * 2003-10-23 2003-10-23 Astrazeneca Ab Novel compounds
AR048523A1 (es) * 2004-04-07 2006-05-03 Kalypsys Inc Compuestos con estructura de aril sulfonamida y sulfonilo como moduladores de ppar y metodos para tratar trastornos metabolicos
US20090118318A1 (en) * 2005-04-04 2009-05-07 Stephen Connolly Novel Diazaspiroalkanes and Their Use for Treatment of CCR8 Mediated Diseases
CA2621164A1 (fr) * 2005-08-26 2007-03-01 Shionogi & Co., Ltd. Derive ayant une activite agoniste vis-a-vis du ppar
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NO20090138L (no) 2009-03-05
WO2007143745A2 (fr) 2007-12-13
EP2044044A2 (fr) 2009-04-08
BRPI0712301A2 (pt) 2012-01-17
AU2007256597A1 (en) 2007-12-13
WO2007143745A3 (fr) 2008-04-17
EA200802415A1 (ru) 2009-06-30
JP2009539880A (ja) 2009-11-19
CN101490024A (zh) 2009-07-22
CA2654784A1 (fr) 2007-12-13

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