CA2652957A1 - Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease - Google Patents

Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease Download PDF

Info

Publication number
CA2652957A1
CA2652957A1 CA002652957A CA2652957A CA2652957A1 CA 2652957 A1 CA2652957 A1 CA 2652957A1 CA 002652957 A CA002652957 A CA 002652957A CA 2652957 A CA2652957 A CA 2652957A CA 2652957 A1 CA2652957 A1 CA 2652957A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
gingivalis
protein
haem
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002652957A
Other languages
English (en)
French (fr)
Inventor
Stuart Geoffrey Dashper
Ching Seng Ang
Paul David Veith
Eric Charles Reynolds
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oral Health Australia Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2006903425A external-priority patent/AU2006903425A0/en
Application filed by Individual filed Critical Individual
Publication of CA2652957A1 publication Critical patent/CA2652957A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002652957A 2006-06-27 2007-06-27 Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease Abandoned CA2652957A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2006903425 2006-06-27
AU2006903425A AU2006903425A0 (en) 2006-06-27 Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
PCT/AU2007/000890 WO2008000028A1 (en) 2006-06-27 2007-06-27 Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Publications (1)

Publication Number Publication Date
CA2652957A1 true CA2652957A1 (en) 2008-01-03

Family

ID=38845037

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002652957A Abandoned CA2652957A1 (en) 2006-06-27 2007-06-27 Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Country Status (6)

Country Link
US (2) US20100092471A1 (enExample)
EP (1) EP2038297A4 (enExample)
JP (1) JP2009544279A (enExample)
AU (1) AU2007264402B2 (enExample)
CA (1) CA2652957A1 (enExample)
WO (1) WO2008000028A1 (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
CN103357014A (zh) * 2007-07-12 2013-10-23 口腔健康澳洲私人有限公司 生物膜治疗
EP2604692A1 (en) 2007-07-12 2013-06-19 Oral Health Australia Pty Ltd Immunology treatment for biofilms
JP2009173558A (ja) * 2008-01-22 2009-08-06 Gen Corp:Kk 抗イヌ歯周病組成物
US8871213B2 (en) 2008-08-29 2014-10-28 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of P. gingivalis infection
RU2012107993A (ru) * 2009-08-02 2013-09-10 Санофи Пастер Лимитид Полипептиды porhyromonas gingivalis
MY162557A (en) 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
TWI542695B (zh) * 2010-12-15 2016-07-21 日星股份有限公司 牙周病原菌血漿或血清抗體價檢查套組
US11191665B2 (en) 2011-02-04 2021-12-07 Joseph E. Kovarik Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
WO2012173244A1 (ja) * 2011-06-17 2012-12-20 国立大学法人東北大学 人獣共通感染性歯周病菌検出用マーカー
JP6310631B2 (ja) * 2011-10-18 2018-04-11 サンスター株式会社 歯周病原菌血漿または血清抗体価検査キット
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US11672835B2 (en) 2013-12-20 2023-06-13 Seed Health, Inc. Method for treating individuals having cancer and who are receiving cancer immunotherapy
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11529379B2 (en) 2013-12-20 2022-12-20 Seed Health, Inc. Method and system for reducing the likelihood of developing colorectal cancer in an individual human being
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11642382B2 (en) 2013-12-20 2023-05-09 Seed Health, Inc. Method for treating an individual suffering from bladder cancer
US12318377B2 (en) 2013-12-20 2025-06-03 Seed Health, Inc. Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
EP4255385A4 (en) * 2021-01-11 2025-03-26 Keystone Bio, Inc. ANTIGEN COMPOSITION(S) AND METHOD(S) AGAINST PORPHYROMONAS GINGIVALIS FOR THE PREVENTION AND/OR TREATMENT OF INFECTIONS AND/OR DISEASES

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210035A (en) * 1980-05-19 1993-05-11 Board Of Trustees Of Leland Stanford Jr. University Non-reventing live vaccines
US4837151A (en) * 1980-05-19 1989-06-06 The Board Of Trustees Of The Leland Stanford Junior University, Stanford University Live vaccines comprising two mutations and foreign antigen
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
US4603112A (en) * 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US5830710A (en) 1988-09-08 1998-11-03 University Of Florida Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
WO1994027606A1 (en) 1993-05-28 1994-12-08 Unisearch Limited Method of treating helicobacter pylori infection
US5711937A (en) 1993-06-28 1998-01-27 Lion Corporation Oral composition
US6017532A (en) 1993-09-10 2000-01-25 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
US5475097A (en) 1993-10-21 1995-12-12 University Of Georgia Research Foundation, Inc. Lysine-specific Porphyromonas gingivalis proteinase
US5523390A (en) 1993-09-10 1996-06-04 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
EP0717747B1 (en) 1993-09-10 2003-06-04 The University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase coding sequences
JPH0797395A (ja) 1993-09-28 1995-04-11 Kyowa Medex Co Ltd ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途
EP0753577B1 (en) 1994-03-29 2002-07-24 Kyowa Hakko Kogyo Co., Ltd. Cell-surface polypeptide gene
AUPN627595A0 (en) 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
AU742668B2 (en) 1996-03-22 2002-01-10 Morehouse School Of Medicine Immunogenic compositions comprising porphyromonas gingivalis peptides and methods
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
EP2264176A1 (en) * 1997-12-10 2010-12-22 CSL Limited Porphorymonas gingivalis polypeptides and polynucleotides
AUPP083997A0 (en) 1997-12-10 1998-01-08 Csl Limited Porphyromonas gingivalis nucleotides
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
US6444799B1 (en) 1997-12-31 2002-09-03 Csl Limited P. gingivalis polynucleotides and uses thereof
AUPP893999A0 (en) * 1999-03-01 1999-03-25 Csl Limited Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
GB9913437D0 (en) 1999-06-09 1999-08-11 Medical Res Council Fusion proteins
AUPQ485999A0 (en) 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
AUPQ718200A0 (en) 2000-04-28 2000-05-25 Csl Limited Porphyromonas gingivalis recombinant proteins and truncations
US6576226B1 (en) 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
GB2381449A (en) 2001-10-31 2003-05-07 Smithkline Beecham Plc Oral hygiene compositions comprising an electron acceptor
DK1660524T3 (da) 2003-08-15 2011-05-09 Univ Florida Identifikation af porphyromonas gingivalis virulens polynukleotider til diagnose, behandling, og monitorering af periodontale sygdomme
EP1721283B1 (en) * 2004-02-06 2022-11-30 Council of Scientific and Industrial Research Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential
WO2006032104A1 (en) 2004-09-23 2006-03-30 The University Of Melbourne Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection
WO2008016385A2 (en) 2006-01-20 2008-02-07 The University Of Washington Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof
WO2008124646A2 (en) 2007-04-06 2008-10-16 The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services Use of amyloid proteins as vaccine scaffolds
CN103357014A (zh) 2007-07-12 2013-10-23 口腔健康澳洲私人有限公司 生物膜治疗
EP2604692A1 (en) 2007-07-12 2013-06-19 Oral Health Australia Pty Ltd Immunology treatment for biofilms
US8871213B2 (en) 2008-08-29 2014-10-28 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of P. gingivalis infection
US20110104179A1 (en) 2009-06-19 2011-05-05 Oral Health Australia Pty Ltd Protease inhibitory peptides

Also Published As

Publication number Publication date
AU2007264402B2 (en) 2012-09-20
US8916166B2 (en) 2014-12-23
WO2008000028A8 (en) 2009-07-16
JP2009544279A (ja) 2009-12-17
WO2008000028A1 (en) 2008-01-03
US20130236488A1 (en) 2013-09-12
EP2038297A4 (en) 2010-03-03
AU2007264402A1 (en) 2008-01-03
EP2038297A1 (en) 2009-03-25
US20100092471A1 (en) 2010-04-15

Similar Documents

Publication Publication Date Title
CA2652957A1 (en) Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
ES2864950T3 (es) Compuestos de 1-ciano-pirrolidina como inhibidores de USP30
Holt et al. Porphyromonas gingivalis, Treponema denticola, andTannerella forsythia: the ‘red complex’, a prototype polybacterial pathogenic consortium in periodontitis.
Roier et al. Intranasal immunization with nontypeable Haemophilus influenzae outer membrane vesicles induces cross-protective immunity in mice
O'Brien-Simpson et al. Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire
Zainal-Abidin et al. Differential proteomic analysis of a polymicrobial biofilm
Pandey et al. A synthetic M protein peptide synergizes with a CXC chemokine protease to induce vaccine-mediated protection against virulent streptococcal pyoderma and bacteremia
JP6178059B2 (ja) エルシニアｓｐｐ．ポリペプチド及び使用方法
US8911745B2 (en) Immunology treatment for biofilms
Hooda et al. Neisserial surface lipoproteins: structure, function and biogenesis
Veith et al. Localization of outer membrane proteins in Treponema denticola by quantitative proteome analyses of outer membrane vesicles and cellular fractions
KR20100063706A (ko) 면역원성 스트렙토코커스 단백질
Weiße et al. Immunogenicity and protective efficacy of a Streptococcus suis vaccine composed of six conserved immunogens
US8911743B2 (en) Haemophilus parasuis polypeptides and methods of use
HK1248535A1 (en) Treatment or prevention of infection
Baarda et al. Proteomics, bioinformatics and structure-function antigen mining for gonorrhea vaccines
Buettner et al. Proteomic and immunoproteomic characterization of a DIVA subunit vaccine against Actinobacillus pleuropneumoniae
AU2013203250B2 (en) Immunology treatment for biofilms
Kossylganova et al. BRUCELLA SPP. ANTIGENS IMPACT IN THE PATHOGENESIS AND DIAGNOSIS OF HUMAN BRUCELLOSIS
Chanda et al. Bridging Gaps in Antibody Responses and Animal Welfare: Assessing Blood Collection Methods and Vaginal Immunity in Mice Immunized with Intranasal Gonococcal Vaccines
Staton Bovine Digital Dermatitis: A Reverse Vaccinology Approach
Khosravani Purification, formulation and characterisation of the adenylate cyclase toxin of Bordetella pertussis
Roier et al. Intranasal Immunization with Nontypeable Haemophilus influenzae Outer
HK1185102A (en) Immunology treatment for biofilms
Vågnes et al. Sera from mice immunized with DNA encoding Porphyromonas gingivalis catalytic or adhesin part of HRgpA inhibit degradation of human fibronectin by HRgpA

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20160629