JP2009544279A - 歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド - Google Patents

歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド Download PDF

Info

Publication number
JP2009544279A
JP2009544279A JP2009516822A JP2009516822A JP2009544279A JP 2009544279 A JP2009544279 A JP 2009544279A JP 2009516822 A JP2009516822 A JP 2009516822A JP 2009516822 A JP2009516822 A JP 2009516822A JP 2009544279 A JP2009544279 A JP 2009544279A
Authority
JP
Japan
Prior art keywords
seq
polypeptide
porphyromonas gingivalis
protein
periodontal disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2009516822A
Other languages
English (en)
Japanese (ja)
Other versions
JP2009544279A5 (enExample
Inventor
スチュアート ジェフリー ダッシュパー
チン セン アン
ポール デイビッド ベイス
エリック チャールズ レイノルズ
Original Assignee
オーラル ヘルス オーストラリア ピーティーワイ リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2006903425A external-priority patent/AU2006903425A0/en
Application filed by オーラル ヘルス オーストラリア ピーティーワイ リミテッド filed Critical オーラル ヘルス オーストラリア ピーティーワイ リミテッド
Publication of JP2009544279A publication Critical patent/JP2009544279A/ja
Publication of JP2009544279A5 publication Critical patent/JP2009544279A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/18—Dental and oral disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2009516822A 2006-06-27 2007-06-27 歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド Pending JP2009544279A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2006903425A AU2006903425A0 (en) 2006-06-27 Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
PCT/AU2007/000890 WO2008000028A1 (en) 2006-06-27 2007-06-27 Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease

Publications (2)

Publication Number Publication Date
JP2009544279A true JP2009544279A (ja) 2009-12-17
JP2009544279A5 JP2009544279A5 (enExample) 2010-09-02

Family

ID=38845037

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009516822A Pending JP2009544279A (ja) 2006-06-27 2007-06-27 歯周病の予防に有用なポルフィロモナス・ジンジバリスポリペプチド

Country Status (6)

Country Link
US (2) US20100092471A1 (enExample)
EP (1) EP2038297A4 (enExample)
JP (1) JP2009544279A (enExample)
AU (1) AU2007264402B2 (enExample)
CA (1) CA2652957A1 (enExample)
WO (1) WO2008000028A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012081306A1 (ja) * 2010-12-15 2012-06-21 サンスター株式会社 歯周病原菌血漿または血清抗体価検査キット
WO2012173244A1 (ja) * 2011-06-17 2012-12-20 国立大学法人東北大学 人獣共通感染性歯周病菌検出用マーカー
JP2013087087A (ja) * 2011-10-18 2013-05-13 Sunstar Inc 歯周病原菌血漿または血清抗体価検査キット
JP2017111095A (ja) * 2015-12-18 2017-06-22 サンスター株式会社 歯周病原菌に対するＩｇＧ抗体の検出方法

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
CN102652831A (zh) * 2007-07-12 2012-09-05 口腔健康澳洲私人有限公司 生物膜的免疫治疗
EP2638905B1 (en) * 2007-07-12 2019-01-16 Oral Health Australia Pty Ltd Biofilm treatment
JP2009173558A (ja) * 2008-01-22 2009-08-06 Gen Corp:Kk 抗イヌ歯周病組成物
EP2328914B1 (en) 2008-08-29 2017-05-10 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of p.gingivalis infection
MX2012001495A (es) * 2009-08-02 2012-08-03 Sanofi Pasteur Ltd Polipeptidos de porphyromonas gingivalis.
MY162557A (en) 2010-02-26 2017-06-15 Oral Health Australia Pty Ltd Treatment or prevention of infection
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US12279989B2 (en) 2011-02-04 2025-04-22 Seed Health, Inc. Method and system for increasing beneficial bacteria and decreasing pathogenic bacteria in the oral cavity
US12533312B2 (en) 2011-02-04 2026-01-27 Seed Health, Inc. Method and system for preventing sore throat in humans
US11998479B2 (en) 2011-02-04 2024-06-04 Seed Health, Inc. Method and system for addressing adverse effects on the oral microbiome and restoring gingival health caused by sodium lauryl sulphate exposure
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11191665B2 (en) 2011-02-04 2021-12-07 Joseph E. Kovarik Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US12257272B2 (en) 2015-12-24 2025-03-25 Seed Health, Inc. Method and system for reducing the likelihood of developing depression in an individual
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US12005085B2 (en) 2013-12-20 2024-06-11 Seed Health, Inc. Probiotic method and composition for maintaining a healthy vaginal microbiome
US12329783B2 (en) 2013-12-20 2025-06-17 Seed Health, Inc. Method and system to improve the health of a person's skin microbiome
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US12246043B2 (en) 2013-12-20 2025-03-11 Seed Health, Inc. Topical application to treat acne vulgaris
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11642382B2 (en) 2013-12-20 2023-05-09 Seed Health, Inc. Method for treating an individual suffering from bladder cancer
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US12318377B2 (en) 2013-12-20 2025-06-03 Seed Health, Inc. Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being
US11998574B2 (en) 2013-12-20 2024-06-04 Seed Health, Inc. Method and system for modulating an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
US11529379B2 (en) 2013-12-20 2022-12-20 Seed Health, Inc. Method and system for reducing the likelihood of developing colorectal cancer in an individual human being
US11672835B2 (en) 2013-12-20 2023-06-13 Seed Health, Inc. Method for treating individuals having cancer and who are receiving cancer immunotherapy
US12637503B2 (en) 2020-11-03 2026-05-26 K-Bio Investment, Llc Antigen-binding molecules that bind to Porphyromonas gingivalis
US20220226454A1 (en) * 2021-01-11 2022-07-21 Keystone Bio, Inc. Antigenic composition(s) and method(s) of use against porphyromonas gingivalis for the prevention and/or treatment of infection and/or diseases

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837151A (en) * 1980-05-19 1989-06-06 The Board Of Trustees Of The Leland Stanford Junior University, Stanford University Live vaccines comprising two mutations and foreign antigen
US5210035A (en) * 1980-05-19 1993-05-11 Board Of Trustees Of Leland Stanford Jr. University Non-reventing live vaccines
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
US4603112A (en) * 1981-12-24 1986-07-29 Health Research, Incorporated Modified vaccinia virus
US5830710A (en) 1988-09-08 1998-11-03 University Of Florida Cloned porphyromonas gingivalis genes and probes for the detection of periodontal disease
WO1994027606A1 (en) 1993-05-28 1994-12-08 Unisearch Limited Method of treating helicobacter pylori infection
AU6983594A (en) 1993-06-28 1995-01-17 Lion Corporation Composition for oral cavity
US5523390A (en) 1993-09-10 1996-06-04 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
US6017532A (en) 1993-09-10 2000-01-25 University Of Georgia Research Foundation, Inc. Porphyromonas gingivalis arginine-specific proteinase
ATE242331T1 (de) 1993-09-10 2003-06-15 Univ Georgia Res Found Porphyromonas gingivalis arginin-spezifische proteinase kodierende sequenzen
US5475097A (en) 1993-10-21 1995-12-12 University Of Georgia Research Foundation, Inc. Lysine-specific Porphyromonas gingivalis proteinase
JPH0797395A (ja) 1993-09-28 1995-04-11 Kyowa Medex Co Ltd ポルフイロモナス・ジンジバリス線毛蛋白質の配列を含有するペプチド類及びその用途
DE69527514T2 (de) 1994-03-29 2003-04-03 Kyowa Hakko Kogyo Co., Ltd. Gen eines zelloberflächenpolypeptids
AUPN627595A0 (en) 1995-10-30 1995-11-23 University Of Melbourne, The Diagnostics and treatments of periodontal disease
JP2000507245A (ja) 1996-03-22 2000-06-13 ユニバーシティー オブ ジョージア リサーチ ファウンデーション，インコーポレイテッド Ｐｏｒｐｈｙｒｏｍｏｎａｓ ｇｉｎｇｉｖａｌｉｓペプチドを含む免疫原性組成物および方法
AUPN901296A0 (en) * 1996-03-29 1996-04-26 University Of Melbourne, The Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
CA2313823A1 (en) * 1997-12-10 1999-06-17 Csl Limited Porphorymonas gingivalis polypeptides and nucleotides
AUPP083997A0 (en) 1997-12-10 1998-01-08 Csl Limited Porphyromonas gingivalis nucleotides
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
US6444799B1 (en) 1997-12-31 2002-09-03 Csl Limited P. gingivalis polynucleotides and uses thereof
AUPP893999A0 (en) * 1999-03-01 1999-03-25 Csl Limited Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with porphyromonas gingivalis
GB9913437D0 (en) 1999-06-09 1999-08-11 Medical Res Council Fusion proteins
AUPQ485999A0 (en) * 1999-12-24 2000-02-03 Csl Limited P. gingivalis antigenic composition
AUPQ718200A0 (en) 2000-04-28 2000-05-25 Csl Limited Porphyromonas gingivalis recombinant proteins and truncations
US6576226B1 (en) 2000-11-17 2003-06-10 Gary R. Jernberg Local delivery of agents for disruption and inhibition of bacterial biofilm for treatment of periodontal disease
GB2381449A (en) 2001-10-31 2003-05-07 Smithkline Beecham Plc Oral hygiene compositions comprising an electron acceptor
ATE495189T1 (de) 2003-08-15 2011-01-15 Univ Florida Die identifikation von polynukleotiden von porphyromonas gingivalis-virulenz zur diagnose, behandlung und beobachtung von periodontalerkrankungen
US7424370B2 (en) * 2004-02-06 2008-09-09 Council Of Scientific And Industrial Research Computational method for identifying adhesin and adhesin-like proteins of therapeutic potential
NZ554331A (en) 2004-09-23 2009-04-30 Univ Melbourne Antigenic complex for the diagnosis and treatment of porphyromonas gingivalis infection
WO2008016385A2 (en) 2006-01-20 2008-02-07 The University Of Washington Deacylase polypeptides, deacylase polynucleotides, and methods of use thereof
WO2008124646A2 (en) 2007-04-06 2008-10-16 The Government Of The U.S.A, As Represented By The Secretary, Dept. Of Health And Human Services Use of amyloid proteins as vaccine scaffolds
CN102652831A (zh) 2007-07-12 2012-09-05 口腔健康澳洲私人有限公司 生物膜的免疫治疗
EP2638905B1 (en) 2007-07-12 2019-01-16 Oral Health Australia Pty Ltd Biofilm treatment
EP2328914B1 (en) 2008-08-29 2017-05-10 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of p.gingivalis infection
WO2010144968A1 (en) 2009-06-19 2010-12-23 Oral Health Australia Pty Ltd Casein derived protease inhibitory peptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012051165; Ｌｉｐｏｐｒｏｔｅｉｎ，　ｐｕｔａｔｉｖｅ． , 20061031 *
JPN6012051168; Ｊ．　Ｂａｃｔｅｒｉｏｌ． ｖｏｌ．１８５，　ｎｏ．１８, 2003, ｐｐ．５５９１-５６０１ *
JPN6013026964; Ｌｉｐｏｐｒｏｔｅｉｎ，　ｐｕｔａｔｉｖｅ． , 20040301 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012081306A1 (ja) * 2010-12-15 2012-06-21 サンスター株式会社 歯周病原菌血漿または血清抗体価検査キット
JPWO2012081306A1 (ja) * 2010-12-15 2014-05-22 サンスター株式会社 歯周病原菌血漿または血清抗体価検査キット
US8975032B2 (en) 2010-12-15 2015-03-10 Sunstar Inc. Test kit for plasma or serum antibody titer against periodontal disease-causing bacteria
WO2012173244A1 (ja) * 2011-06-17 2012-12-20 国立大学法人東北大学 人獣共通感染性歯周病菌検出用マーカー
JP2013087087A (ja) * 2011-10-18 2013-05-13 Sunstar Inc 歯周病原菌血漿または血清抗体価検査キット
JP2017111095A (ja) * 2015-12-18 2017-06-22 サンスター株式会社 歯周病原菌に対するＩｇＧ抗体の検出方法

Also Published As

Publication number Publication date
US20130236488A1 (en) 2013-09-12
AU2007264402B2 (en) 2012-09-20
WO2008000028A1 (en) 2008-01-03
WO2008000028A8 (en) 2009-07-16
US8916166B2 (en) 2014-12-23
US20100092471A1 (en) 2010-04-15
EP2038297A1 (en) 2009-03-25
CA2652957A1 (en) 2008-01-03
AU2007264402A1 (en) 2008-01-03
EP2038297A4 (en) 2010-03-03

Similar Documents

Publication Publication Date Title
US8916166B2 (en) Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
US8911745B2 (en) Immunology treatment for biofilms
WO2004078949A2 (en) Genes of an otitis media isolate of nontypeable haemophilus influenzae
JP2017503792A (ja) ＯｓｐＡの突然変異体断片、並びにそれに関する方法および使用
CN114423448A (zh) 疫苗组合物和选择抗原的方法
US9597386B2 (en) Outer membrane proteins of Histophilus somni and methods thereof
Frazer et al. Vaccination with recombinant adhesins from the RgpA–Kgp proteinase–adhesin complex protects against Porphyromonas gingivalis infection
RU2766354C2 (ru) Вакцинные конструкты и их применения против инфекций стафилококка
RU2555530C2 (ru) СПОСОБ ИДЕНТИФИКАЦИИ ПОЛИПЕПТИДОВ И БЕЛКОВ H.parasuis
WO2013033092A2 (en) Streptococcus suis pilus antigens
CN103687613A (zh) 蛋白f-具有层粘连蛋白和玻连蛋白结合性能的新的流感嗜血杆菌粘附素
AU2013203250B2 (en) Immunology treatment for biofilms
HK1185102A (en) Immunology treatment for biofilms
Roier et al. Intranasal Immunization with Nontypeable Haemophilus influenzae Outer
HK1149770B (en) Compositions, methods and kits

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20100623

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20100623

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20121002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20121225

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130107

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130329

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20130402

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130604

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20130822

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20130829

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20131025

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20131217