CA2650836C - Multilayer silk protein films - Google Patents
Multilayer silk protein films Download PDFInfo
- Publication number
- CA2650836C CA2650836C CA 2650836 CA2650836A CA2650836C CA 2650836 C CA2650836 C CA 2650836C CA 2650836 CA2650836 CA 2650836 CA 2650836 A CA2650836 A CA 2650836A CA 2650836 C CA2650836 C CA 2650836C
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- CA
- Canada
- Prior art keywords
- spider silk
- multilayer film
- films
- multilayer
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
- C08J5/18—Manufacture of films or sheets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
- C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D189/00—Coating compositions based on proteins; Coating compositions based on derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2389/00—Characterised by the use of proteins; Derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31725—Of polyamide
- Y10T428/3175—Next to addition polymer from unsaturated monomer[s]
- Y10T428/31754—Natural source-type polyamide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31725—Of polyamide
- Y10T428/31768—Natural source-type polyamide [e.g., casein, gelatin, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Manufacturing & Machinery (AREA)
- Insects & Arthropods (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Laminated Bodies (AREA)
- Materials For Medical Uses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20060113438 EP1852470A1 (en) | 2006-05-03 | 2006-05-03 | Multilayer Silk Protein Films |
| EP06113438.3 | 2006-05-03 | ||
| PCT/EP2007/003304 WO2007128378A1 (en) | 2006-05-03 | 2007-04-13 | Multilayer silk protein films |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2650836A1 CA2650836A1 (en) | 2007-11-15 |
| CA2650836C true CA2650836C (en) | 2014-05-27 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA 2650836 Active CA2650836C (en) | 2006-05-03 | 2007-04-13 | Multilayer silk protein films |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20090263430A1 (enExample) |
| EP (2) | EP1852470A1 (enExample) |
| JP (1) | JP2009535242A (enExample) |
| KR (1) | KR20090023365A (enExample) |
| CN (1) | CN101460570B (enExample) |
| AU (1) | AU2007247539C1 (enExample) |
| CA (1) | CA2650836C (enExample) |
| RU (1) | RU2008146255A (enExample) |
| WO (1) | WO2007128378A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101395178B (zh) | 2005-12-30 | 2013-05-01 | 思百博技术股份公司 | 蜘蛛丝蛋白和用于产生蜘蛛丝蛋白的方法 |
| CA2704768A1 (en) * | 2006-11-03 | 2008-10-23 | Trustees Of Tufts College | Biopolymer sensor and method of manufacturing the same |
| EP2650112B1 (en) | 2006-11-03 | 2016-08-24 | Trustees Of Tufts College | Nanopatterned biopolymer optical device and method of manufacturing the same |
| US8574461B2 (en) | 2006-11-03 | 2013-11-05 | Tufts University | Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same |
| CA2690658C (en) * | 2007-06-20 | 2016-08-09 | Basf Se | Synthetic repetitive proteins, their production and use thereof |
| GB2461125A (en) * | 2008-06-25 | 2009-12-30 | Spintec Engineering Gmbh | A silk membrane for bone graft material |
| US20110136669A1 (en) | 2008-08-08 | 2011-06-09 | Basf Se | Continuous Fiber Layer Comprising an Active Substance on the Basis of Bio-Polymers, the use Thereof, and Method for the Production Thereof |
| GB2464348A (en) * | 2008-10-17 | 2010-04-21 | Spintec Engineering Gmbh | Applying a liquid protein onto a permeable surface, and silk mono-filament having specific properties |
| PL2435102T3 (pl) * | 2009-05-28 | 2021-01-11 | Addbio Ab | Wielowarstwowe folie białkowe, sposoby ich wytwarzania, urządzenia do podawania leku oraz implanty biomedyczne wykorzystujące folie |
| EP3495381A1 (en) * | 2009-12-08 | 2019-06-12 | AMSilk GmbH | Silk protein coatings |
| RU2443805C1 (ru) * | 2010-08-20 | 2012-02-27 | Государственное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный университет технологии и дизайна" (СПГУТД) | Способ получения пленки на основе фиброина шелка для изготовления контактных линз |
| DK3178843T3 (da) | 2010-10-27 | 2019-08-19 | Spiber Tech Ab | Edderkoppesilke-fusionsproteinstrukturer til at binde til et organisk mål |
| US20120236298A1 (en) * | 2011-03-15 | 2012-09-20 | Michael Josef Stuke | Tunable apparatus for performing sers |
| CA2833144C (en) | 2011-04-14 | 2020-09-29 | The Regents Of The University Of California | Multilayer thin film drug delivery device and methods of making and using the same |
| US20140378661A1 (en) * | 2011-04-20 | 2014-12-25 | Trustees Of Tufts College | Molded regenerated silk geometries using temperature control and mechanical processing |
| US9956387B2 (en) | 2011-07-08 | 2018-05-01 | Timothy Brown | Article of clothing for applying a pharmaceutical, a pharmaceutical delivery kit and method |
| US9377409B2 (en) | 2011-07-29 | 2016-06-28 | Hewlett-Packard Development Company, L.P. | Fabricating an apparatus for use in a sensing application |
| HK1205953A1 (en) | 2012-03-20 | 2015-12-31 | Trustees Of Tufts College | Silk reservoirs for drug delivery |
| CN104470607B (zh) | 2012-05-02 | 2017-04-05 | 思百博技术股份公司 | 作为亲和配体的掺入有免疫球蛋白片段的蜘蛛丝融合蛋白结构 |
| US9708376B2 (en) | 2012-05-02 | 2017-07-18 | Spiber Technologies Ab | Spider silk fusion protein structures without repetitive fragment for binding to an organic target |
| WO2014103799A1 (ja) | 2012-12-26 | 2014-07-03 | スパイバー株式会社 | クモ糸タンパク質フィルム及びその製造方法 |
| CN103341214B (zh) * | 2013-07-08 | 2014-12-31 | 苏州大学 | 一种丝素蛋白膜及其制备方法 |
| WO2015117888A1 (en) * | 2014-02-04 | 2015-08-13 | Amsilk Gmbh | Coated silk films, methods for the production thereof and uses thereof |
| CN104323927A (zh) * | 2014-11-06 | 2015-02-04 | 济南星河康泰贸易有限公司 | 贻贝粘蛋白在制备皮肤美容化妆品上的应用 |
| JP6693049B2 (ja) * | 2015-05-21 | 2020-05-13 | 日立化成株式会社 | ナノ薄膜転写シート及び転写方法 |
| JP6544040B2 (ja) * | 2015-05-21 | 2019-07-17 | 日立化成株式会社 | フィブロインナノ薄膜、ナノ薄膜シート及び転写方法 |
| CN105297440B (zh) * | 2015-11-11 | 2018-01-12 | 浙江理工大学 | 一种对蚕丝接枝改性的方法 |
| EP3207947A1 (en) * | 2016-02-17 | 2017-08-23 | Ruprecht-Karls-Universität Heidelberg | Bioactive compound delivery assembly |
| US11298443B2 (en) | 2016-07-01 | 2022-04-12 | Trustees Of Tufts College | Innervated artificial skin |
| CN106188923A (zh) * | 2016-08-04 | 2016-12-07 | 叶剑 | 一种聚苯乙烯基复合装饰板及其制造方法 |
| US12059826B2 (en) | 2017-09-26 | 2024-08-13 | Spiber Technologies Ab | Structuring of surface-active macromolecules |
| JP2021080304A (ja) * | 2018-01-26 | 2021-05-27 | Ｓｐｉｂｅｒ株式会社 | タンパク質成形体用素材、タンパク質成形体、及びタンパク質成形体の製造方法 |
| JP6743939B2 (ja) * | 2019-05-09 | 2020-08-19 | 日立化成株式会社 | ナノ薄膜転写シート及び転写方法 |
| WO2021113054A2 (en) * | 2019-11-13 | 2021-06-10 | Rapp Robert James | Spider silk proteins - small particle process and products |
| CN113652033B (zh) * | 2021-08-22 | 2022-12-06 | 茂泰(福建)鞋材有限公司 | 一种贻贝足丝防滑橡胶鞋底的制备方法 |
| US20240002682A1 (en) * | 2022-07-01 | 2024-01-04 | Ayro, Inc. | Coating gradient property management for sustainable vehicles, systems, methods, and apparatus |
| CN116285719A (zh) * | 2022-09-09 | 2023-06-23 | 之江实验室 | 一种丝素蛋白塑封膜及其制备方法和应用 |
| EP4598983A1 (en) | 2022-10-03 | 2025-08-13 | Xampla Limited | Alginate-starch films |
| CN116103933B (zh) * | 2023-02-21 | 2024-08-13 | 现代纺织技术创新中心(鉴湖实验室) | 一种高牢度双层组合丝素蛋白涂层织物的制备方法 |
| CN117445491A (zh) * | 2023-12-06 | 2024-01-26 | 江西丝科生物科技有限公司 | 一种蛋白膜的复合方法及复合蛋白膜 |
| WO2025202394A1 (en) | 2024-03-29 | 2025-10-02 | XAMPLA Ltd. | Bilayer film |
| WO2025202391A1 (en) | 2024-03-29 | 2025-10-02 | XAMPLA Ltd. | Triple layer film |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2405850A1 (en) * | 2001-03-14 | 2002-10-10 | Tetsuo Asakura | Method for producing fiber and film of silk and silk-like material |
| US7057023B2 (en) * | 2002-01-11 | 2006-06-06 | Nexia Biotechnologies Inc. | Methods and apparatus for spinning spider silk protein |
| WO2004000915A2 (en) * | 2002-06-24 | 2003-12-31 | Tufts University | Silk biomaterials and methods of use thereof |
| US7160299B2 (en) * | 2003-05-01 | 2007-01-09 | Sherwood Services Ag | Method of fusing biomaterials with radiofrequency energy |
| US7348399B2 (en) * | 2003-08-29 | 2008-03-25 | Louisiana Tech University Foundation, Inc. | Nanofabricated polypeptide multilayer films, coatings, and microcapsules |
-
2006
- 2006-05-03 EP EP20060113438 patent/EP1852470A1/en not_active Withdrawn
-
2007
- 2007-04-13 WO PCT/EP2007/003304 patent/WO2007128378A1/en not_active Ceased
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- 2007-04-13 AU AU2007247539A patent/AU2007247539C1/en active Active
- 2007-04-13 RU RU2008146255/04A patent/RU2008146255A/ru not_active Application Discontinuation
- 2007-04-13 US US12/226,854 patent/US20090263430A1/en not_active Abandoned
- 2007-04-13 KR KR1020087029623A patent/KR20090023365A/ko not_active Withdrawn
- 2007-04-13 JP JP2009508152A patent/JP2009535242A/ja not_active Withdrawn
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Also Published As
| Publication number | Publication date |
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| JP2009535242A (ja) | 2009-10-01 |
| EP2013290A1 (en) | 2009-01-14 |
| KR20090023365A (ko) | 2009-03-04 |
| CN101460570A (zh) | 2009-06-17 |
| CN101460570B (zh) | 2012-09-05 |
| WO2007128378A1 (en) | 2007-11-15 |
| AU2007247539B2 (en) | 2013-03-28 |
| CA2650836A1 (en) | 2007-11-15 |
| EP2013290B1 (en) | 2013-06-12 |
| AU2007247539A1 (en) | 2007-11-15 |
| RU2008146255A (ru) | 2010-06-20 |
| US20090263430A1 (en) | 2009-10-22 |
| AU2007247539C1 (en) | 2013-08-15 |
| EP1852470A1 (en) | 2007-11-07 |
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