CA2649894A1 - The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 - Google Patents

The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 Download PDF

Info

Publication number
CA2649894A1
CA2649894A1 CA002649894A CA2649894A CA2649894A1 CA 2649894 A1 CA2649894 A1 CA 2649894A1 CA 002649894 A CA002649894 A CA 002649894A CA 2649894 A CA2649894 A CA 2649894A CA 2649894 A1 CA2649894 A1 CA 2649894A1
Authority
CA
Canada
Prior art keywords
glucocorticoid receptor
receptor antagonist
beta
phenyl
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002649894A
Other languages
English (en)
French (fr)
Inventor
Joseph K. Belanoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corcept Therapeutics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2649894A1 publication Critical patent/CA2649894A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002649894A 2006-05-02 2007-05-02 The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 Abandoned CA2649894A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US79726506P 2006-05-02 2006-05-02
US60/797,265 2006-05-02
PCT/US2007/068044 WO2007131041A2 (en) 2006-05-02 2007-05-02 The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2

Publications (1)

Publication Number Publication Date
CA2649894A1 true CA2649894A1 (en) 2007-11-15

Family

ID=38668513

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002649894A Abandoned CA2649894A1 (en) 2006-05-02 2007-05-02 The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2

Country Status (5)

Country Link
EP (1) EP2012796A4 (https=)
JP (1) JP2009535430A (https=)
AU (1) AU2007248059A1 (https=)
CA (1) CA2649894A1 (https=)
WO (1) WO2007131041A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20110702T1 (hr) 2007-02-02 2011-10-31 Pfizer Products Inc. Triciklički spojevi i njihova uporaba kao modulatora glukokortikoidnih receptora
EP2114888B1 (en) * 2007-02-02 2010-11-10 Pfizer Products Inc. Tricyclic compounds and their use as glucocorticoid receptor modulators
ES2865334T3 (es) 2015-08-13 2021-10-15 Corcept Therapeutics Inc Método de diagnóstico diferencial de síndrome de Cushing dependiente de ACTH
EP4406611A3 (en) * 2016-01-11 2024-10-23 Dignity Health Modulators of zinc activated cation channel
CN115053861A (zh) * 2022-06-30 2022-09-16 南方医科大学南方医院 一种基于免疫激活的精神分裂症动物模型的构建方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE332696T1 (de) * 1997-10-06 2006-08-15 Univ Leland Stanford Junior Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
KR20050038580A (ko) * 2001-10-26 2005-04-27 악조 노벨 엔.브이. 주요 우울 장애의 치료에 사용되는(11β,17β)-11-(1,3-벤조디옥솔-5-일)-17-히드록시-17-(1-프로피닐)-에스트라-4,9-디엔-3-온의 용도
WO2003043640A2 (en) * 2001-11-23 2003-05-30 Akzo Nobel N.V. Treatment of major depressive disorder using glucocorticoid receptor antagonists
JP2006508951A (ja) * 2002-11-05 2006-03-16 コーセプト セラピューティクス, インコーポレイテッド 片頭痛を処置するための方法

Also Published As

Publication number Publication date
WO2007131041A2 (en) 2007-11-15
EP2012796A4 (en) 2010-08-11
JP2009535430A (ja) 2009-10-01
AU2007248059A1 (en) 2007-11-15
EP2012796A2 (en) 2009-01-14
WO2007131041A3 (en) 2008-10-09

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20140502