CA2649701A1 - Use of organic compounds - Google Patents
Use of organic compounds Download PDFInfo
- Publication number
- CA2649701A1 CA2649701A1 CA002649701A CA2649701A CA2649701A1 CA 2649701 A1 CA2649701 A1 CA 2649701A1 CA 002649701 A CA002649701 A CA 002649701A CA 2649701 A CA2649701 A CA 2649701A CA 2649701 A1 CA2649701 A1 CA 2649701A1
- Authority
- CA
- Canada
- Prior art keywords
- disease
- diabetes
- agonist
- err
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79722806P | 2006-05-03 | 2006-05-03 | |
US60/797,228 | 2006-05-03 | ||
PCT/US2007/067971 WO2007131005A2 (en) | 2006-05-03 | 2007-05-02 | Use of organic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2649701A1 true CA2649701A1 (en) | 2007-11-15 |
Family
ID=38477124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002649701A Abandoned CA2649701A1 (en) | 2006-05-03 | 2007-05-02 | Use of organic compounds |
Country Status (13)
Country | Link |
---|---|
US (1) | US20090281191A1 (de) |
EP (1) | EP2015777B1 (de) |
JP (1) | JP2009535425A (de) |
KR (1) | KR20090005137A (de) |
CN (1) | CN101432024A (de) |
AT (1) | ATE477819T1 (de) |
AU (1) | AU2007248112A1 (de) |
BR (1) | BRPI0711174A2 (de) |
CA (1) | CA2649701A1 (de) |
DE (1) | DE602007008553D1 (de) |
MX (1) | MX2008014008A (de) |
RU (1) | RU2008147269A (de) |
WO (1) | WO2007131005A2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5935030B2 (ja) | 2010-05-14 | 2016-06-15 | ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド | 白血病を治療するための組成物および方法 |
WO2011143657A1 (en) | 2010-05-14 | 2011-11-17 | Dana-Farber Cancer Institute, Inc. | Male contraceptive compositions and methods of use |
HUE031073T2 (en) | 2010-05-14 | 2017-06-28 | Dana Farber Cancer Inst Inc | Thieno triazolo-diazepine compounds for the treatment of neoplasia |
US8962546B2 (en) | 2011-03-01 | 2015-02-24 | Salk Institute For Biological Studies | Modulation of estrogen receptor-related receptor gamma (ERRγ) and uses therefor |
US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2766349B1 (de) | 2011-03-08 | 2016-06-01 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
US8828994B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
EP2567959B1 (de) | 2011-09-12 | 2014-04-16 | Sanofi | 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridin-4-carbonsäureamid-derivate als kinaseinhibitoren |
WO2014159392A1 (en) | 2013-03-14 | 2014-10-02 | Dana-Farber Cancer Institute, Inc. | Bromodomain binding reagents and uses thereof |
WO2014205045A1 (en) * | 2013-06-18 | 2014-12-24 | Downes, Michael | Methods of treating muscular dystrophy |
BR112016001457A2 (pt) | 2013-07-25 | 2017-08-29 | Dana Farber Cancer Inst Inc | Inibidores de fatores de transcrição e usos dos mesmos |
MX2016005980A (es) | 2013-11-08 | 2016-12-09 | Dana Farber Cancer Inst Inc | Terapia de combinación para el cáncer usando inhibidores de la proteína bromodominio y extra-terminal. |
CA2936865A1 (en) | 2014-01-31 | 2015-08-06 | Dana-Farber Cancer Institute, Inc. | Diaminopyrimidine benzenesulfone derivatives and uses thereof |
US10793571B2 (en) | 2014-01-31 | 2020-10-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
JP2017504650A (ja) | 2014-01-31 | 2017-02-09 | ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド | ジアゼパン誘導体およびその使用 |
MX2016011160A (es) | 2014-02-28 | 2017-04-27 | Tensha Therapeutics Inc | Tratamiento de afecciones asociadas con la hiperinsulinemia. |
MX2017001757A (es) | 2014-08-08 | 2017-05-30 | Dana Farber Cancer Inst Inc | Derivados de dihidropteridinona y sus usos. |
WO2016022902A1 (en) | 2014-08-08 | 2016-02-11 | Dana-Farber Cancer Institute, Inc. | Diazepane derivatives and uses thereof |
PE20171042A1 (es) | 2014-10-27 | 2017-07-19 | Tensha Therapeutics Inc | Inhibidores del bromodominio |
JP6495468B2 (ja) | 2015-02-27 | 2019-04-03 | ソーク インスティチュート フォー バイオロジカル スタディーズ | リプログラミング前駆体組成物およびその使用方法 |
AU2016276963C1 (en) | 2015-06-12 | 2021-08-05 | Dana-Farber Cancer Institute, Inc. | Combination therapy of transcription inhibitors and kinase inhibitors |
KR20180051576A (ko) | 2015-09-11 | 2018-05-16 | 다나-파버 캔서 인스티튜트 인크. | 아세트아미드 티에노트리아졸로디아제핀 및 그의 용도 |
MX2018003031A (es) | 2015-09-11 | 2018-08-01 | Dana Farber Cancer Inst Inc | Ciano tienotriazolpirazinas y usos de las mismas. |
WO2017053084A1 (en) * | 2015-09-25 | 2017-03-30 | Salk Institute For Biological Studies | Estrogen related receptor gamma (erry) enhances and maintains brown fat thermogenic capacity |
SG11201803210YA (en) | 2015-11-25 | 2018-05-30 | Dana Farber Cancer Inst Inc | Bivalent bromodomain inhibitors and uses thereof |
AU2017269364B2 (en) | 2016-05-25 | 2023-08-31 | Salk Institute For Biological Studies | Compositions and methods for organoid generation and disease modeling |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2005514921A (ja) * | 2001-11-09 | 2005-05-26 | ダナ−ファーバー キャンサー インスティチュート インク | PGC−1β、新規PGC−1相同体およびその用途 |
EP1548434A4 (de) * | 2002-08-08 | 2007-05-09 | Japan Science & Tech Agency | Verfahren zum screening eines medikaments |
US20050074765A1 (en) * | 2002-10-16 | 2005-04-07 | Blanchard Steven G. | Methods for identifying and using modulators of estrogen related receptor gamma |
WO2006130503A2 (en) * | 2005-05-27 | 2006-12-07 | Janssen Pharmaceutica N.V. | Errϝ peptide fragment complexes and uses thereof in drug discovery |
-
2007
- 2007-05-02 RU RU2008147269/14A patent/RU2008147269A/ru not_active Application Discontinuation
- 2007-05-02 DE DE602007008553T patent/DE602007008553D1/de active Active
- 2007-05-02 EP EP07783060A patent/EP2015777B1/de not_active Revoked
- 2007-05-02 AT AT07783060T patent/ATE477819T1/de not_active IP Right Cessation
- 2007-05-02 JP JP2009510039A patent/JP2009535425A/ja active Pending
- 2007-05-02 KR KR1020087026812A patent/KR20090005137A/ko not_active Application Discontinuation
- 2007-05-02 CA CA002649701A patent/CA2649701A1/en not_active Abandoned
- 2007-05-02 AU AU2007248112A patent/AU2007248112A1/en not_active Abandoned
- 2007-05-02 CN CNA2007800155975A patent/CN101432024A/zh active Pending
- 2007-05-02 US US12/299,256 patent/US20090281191A1/en not_active Abandoned
- 2007-05-02 BR BRPI0711174-6A patent/BRPI0711174A2/pt not_active IP Right Cessation
- 2007-05-02 MX MX2008014008A patent/MX2008014008A/es not_active Application Discontinuation
- 2007-05-02 WO PCT/US2007/067971 patent/WO2007131005A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
JP2009535425A (ja) | 2009-10-01 |
EP2015777A2 (de) | 2009-01-21 |
AU2007248112A1 (en) | 2007-11-15 |
DE602007008553D1 (de) | 2010-09-30 |
BRPI0711174A2 (pt) | 2011-08-23 |
KR20090005137A (ko) | 2009-01-12 |
EP2015777B1 (de) | 2010-08-18 |
WO2007131005A2 (en) | 2007-11-15 |
CN101432024A (zh) | 2009-05-13 |
MX2008014008A (es) | 2009-03-25 |
US20090281191A1 (en) | 2009-11-12 |
RU2008147269A (ru) | 2010-06-10 |
WO2007131005A3 (en) | 2008-06-19 |
ATE477819T1 (de) | 2010-09-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US20090281191A1 (en) | Use of organic compounds | |
Song et al. | Abnormal kynurenine pathway of tryptophan catabolism in cardiovascular diseases | |
Li et al. | Vascular insulin resistance in prehypertensive rats: role of PI3-kinase/Akt/eNOS signaling | |
Caldwell et al. | Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51 | |
Consitt et al. | Peroxisome proliferator–activated receptor-γ coactivator-1α overexpression increases lipid oxidation in myocytes from extremely obese individuals | |
Zhou et al. | Melatonin inhibits glucose-induced apoptosis in osteoblastic cell line through PERK-eIF2α-ATF4 pathway | |
Baer et al. | Panic attacks and the dexamethasone suppression test | |
US8058316B2 (en) | STAT3 inhibiting compositions and methods | |
Ding et al. | Insulin resistance disrupts the interaction between AKT and the NMDA receptor and the inactivation of the CaMKIV/CREB pathway in minimal hepatic encephalopathy | |
Tanis et al. | The effect of glucose concentration and sodium phenylbutyrate treatment on mitochondrial bioenergetics and ER stress in 3T3-L1 adipocytes | |
Brown et al. | The APOE4 genotype alters the response of microglia and macrophages to 17β-estradiol | |
Li et al. | HIGD1A links SIRT1 activity to adipose browning by inhibiting the ROS/DNA damage pathway | |
Pei et al. | Downregulation of chemerin and alleviation of endoplasmic reticulum stress by metformin in adipose tissue of rats | |
JP2005523004A (ja) | グルコース取り込みの増加及びii型糖尿病の治療のためのnad(p)hオキシダーゼ阻害剤 | |
JP5901770B2 (ja) | Cyp4a阻害剤を有効成分として含有する糖尿病又は脂肪肝の予防又は治療用薬学的組成物。 | |
Xiao et al. | Mitochondrial energetic impairment in a patient with late‐onset glutaric acidemia Type 2 | |
Gao et al. | Oxidative stress increases the risk of pancreatic β cell damage in chronic renal hypertensive rats | |
Wang et al. | Teneligliptin alleviates diabetes-related cognitive impairment by inhibiting the endoplasmic reticulum (ER) stress and NLRP3 inflammasome in mice | |
WO2010007085A2 (en) | Use of organic compounds | |
Wang et al. | Insulin and adipokine signaling and their cross-regulation in postmortem human brain | |
US20170087145A1 (en) | Gapdh cascade inhibitor compounds and methods of use and treatment of stress induced disorders including mental illness | |
WO2005085846A1 (ja) | 虚血性心疾患危険群診断薬 | |
Kasuno et al. | Urinary thioredoxin as a biomarker of renal redox dysregulation and a companion diagnostic to identify responders to redox-modulating therapeutics | |
US10376484B2 (en) | Combination of bezafibrate and of resveratrol or resveratrol derivatives for the treatment and prevention of diseases involving a mitochondrial energy dysfunction | |
Tvarijonaviciute et al. | Serum adiponectin concentration in dogs—absence of diurnal variation and lack of effect of feeding and methylprednisolone administration |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |