CA2645871A1 - PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-ASSOCIATED DISEASE - Google Patents

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-ASSOCIATED DISEASE

Info

Publication number
CA2645871A1
CA2645871A1 CA002645871A CA2645871A CA2645871A1 CA 2645871 A1 CA2645871 A1 CA 2645871A1 CA 002645871 A CA002645871 A CA 002645871A CA 2645871 A CA2645871 A CA 2645871A CA 2645871 A1 CA2645871 A1 CA 2645871A1
Authority
CA
Canada
Prior art keywords
treating
methods
pharmaceutical compositions
related disease
preventing oxalate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA002645871A
Other languages
English (en)
French (fr)
Inventor
Harmeet Sidhu
Poonam Kaul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxthera Inc
Original Assignee
Oxthera Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxthera Inc filed Critical Oxthera Inc
Publication of CA2645871A1 publication Critical patent/CA2645871A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pregnancy & Childbirth (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
CA002645871A 2005-12-14 2005-12-14 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-ASSOCIATED DISEASE Pending CA2645871A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2005/045457 WO2007070052A2 (en) 2005-12-14 2005-12-14 Pharmaceutical compositions and methods for treating or preventing oxalate-related disease

Publications (1)

Publication Number Publication Date
CA2645871A1 true CA2645871A1 (en) 2007-06-21

Family

ID=36581703

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002645871A Pending CA2645871A1 (en) 2005-12-14 2005-12-14 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OXALATE-ASSOCIATED DISEASE
CA2650122A Active CA2650122C (en) 2005-12-14 2006-12-14 Pharmaceutical compositions and methods for treating or preventing oxalate-related disease

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2650122A Active CA2650122C (en) 2005-12-14 2006-12-14 Pharmaceutical compositions and methods for treating or preventing oxalate-related disease

Country Status (14)

Country Link
US (2) US20100028422A1 (enExample)
EP (2) EP1962873B1 (enExample)
JP (2) JP5047190B2 (enExample)
AU (2) AU2005339139A1 (enExample)
CA (2) CA2645871A1 (enExample)
CY (2) CY1114397T1 (enExample)
DK (1) DK1962873T3 (enExample)
ES (2) ES2426258T3 (enExample)
HU (1) HUE034539T2 (enExample)
LT (1) LT1965816T (enExample)
PL (2) PL1962873T3 (enExample)
PT (1) PT1962873E (enExample)
SI (1) SI1962873T1 (enExample)
WO (2) WO2007070052A2 (enExample)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8486389B2 (en) 1997-05-23 2013-07-16 Oxthera, Inc. Compositions and methods for treating or preventing oxalate-related disease
AU2005339139A1 (en) * 2005-12-14 2007-06-21 Oxthera, Inc. Pharmaceutical compositions and methods for treating or preventing oxalate-related disease
JP5558002B2 (ja) 2005-12-16 2014-07-23 オクセラ インコーポレイテッド シュウ酸塩低減化のための組成物および方法
DK2046373T3 (da) 2006-08-02 2013-05-27 Althea Technologies Inc Krystalliseret oxalatdecarboxylase og fremgangsmåder til anvendelse
GB2463181B (en) 2007-05-14 2013-03-27 Univ New York State Res Found Induction of a physiological dispersion response in bacterial cells in a biofilm
US9283252B2 (en) 2008-09-30 2016-03-15 Meiji Co., Ltd. Lactic acid bacterium having high oxalic acid decomposition ability
FR2936952A1 (fr) * 2008-10-09 2010-04-16 Monique Bellec Administration par voie orale de medicaments et complements nutritionnels
DK2270138T3 (en) 2009-07-02 2018-06-25 Oxthera Intellectual Property Ab Purification and isolation of recombinant oxalate-degrading enzymes
ES2617917T3 (es) * 2009-07-02 2017-06-20 Oxthera Intellectual Property Ab Purificación y aislamiento de enzimas de degradación de oxalato recombinantes y partículas secadas por atomización que contienen enzimas de degradación de oxalato
US8431122B2 (en) 2009-07-02 2013-04-30 Oxthera Intellectual Property Ab Purification and isolation of recombinant oxalate degrading enzymes and spray-dried particles containing oxalate degrading enzymes
US20110070334A1 (en) * 2009-09-20 2011-03-24 Nagendra Rangavajla Probiotic Stabilization
WO2011066282A2 (en) * 2009-11-25 2011-06-03 Captozyme, Llc Methods and compositions for treating oxalate-related conditions
HK1253538A1 (en) * 2010-08-04 2019-06-21 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them
BR112013002667B1 (pt) * 2010-08-04 2020-02-04 Thomas Julius Borody composições para transplante da flora intestinal e métodos para fazê-las e usá-las e dispositivos para administrá-las
US20140112985A1 (en) * 2012-10-22 2014-04-24 Polonez Therapeutics Llc Method of prevention and treatment of clostridium difficile infection
WO2014113648A1 (en) 2013-01-18 2014-07-24 Allena Pharmaceuticals, Inc. Crystallized oxalate decarboxylase and methods of use
US11077238B2 (en) 2013-06-07 2021-08-03 Allena Pharmaceuticals, Inc. Compositions, methods, and devices for dialysis
WO2015002588A1 (en) 2013-07-05 2015-01-08 Oxthera Intellectual Property Ab Secretagogues derived from oxalobacter formigenes
PT3087178T (pt) * 2013-12-23 2018-11-21 Nexttobe Ab Método para produzir oxalato oxidases que têm atividade ótica próxima ao ph fisiológico e utilização de tais oxalato oxidases recombinantes no tratamento de doenças relacionadas com oxalato
EP3164145A4 (en) 2014-07-01 2018-01-17 Probi Usa, Inc. Bi-layer dual release probiotic tablets
AU2016244121B2 (en) 2015-04-02 2020-11-05 Orenzymes Llc High efficiency oxalate-degrading enzymes for degradation of insoluble and soluble oxalate
FR3045384B1 (fr) * 2015-12-18 2020-02-07 Institut National De La Recherche Agronomique Composition lyophilisee pour la conservation de microbiote dans son ecosysteme
CN106974262B (zh) * 2016-01-15 2021-05-25 深圳华大生命科学研究院 肠道益生杆菌在治疗和预防肥胖及其相关疾病中的应用
EP3426263A4 (en) * 2016-03-09 2019-10-16 Incube Labs, LLC METHOD AND ARTICLE FOR THE DELIVERY OF LIVABLE CELLS IN SOLID TISSUE
CA3023042A1 (en) * 2016-06-13 2017-12-21 Oxthera Intellectual Property Ab Compositions and methods for the treatment or prevention of oxalate-related disorders
WO2018218159A1 (en) 2017-05-26 2018-11-29 Crestovo Holdings Llc Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same
HUE069333T2 (hu) 2017-11-17 2025-02-28 Evonik Operations Gmbh Eljárás bevonatos kemény héjú kapszula elõállítására
CN110734861B (zh) * 2018-07-20 2022-02-11 中国农业大学 一种猪肠道食糜微生物组的体外保藏方法
JP2020055755A (ja) * 2018-09-28 2020-04-09 日本ケミファ株式会社 腸溶性製剤
WO2020071994A1 (en) * 2018-10-04 2020-04-09 Oxthera Intellectual Property Ab New medical use of oxalate-reducing bacteria
EP3646857A1 (en) * 2018-11-01 2020-05-06 Evonik Operations GmbH Colonic delivery system for microorganisms
CN109402022A (zh) * 2018-12-05 2019-03-01 上海上药信谊药厂有限公司 一种产甲酸草酸杆菌及其应用
US20230092431A1 (en) * 2020-01-14 2023-03-23 Synlogic Operating Company, Inc. Bacteria engineered to treat disorders in which oxalate is detrimental
US20230107049A1 (en) * 2020-02-28 2023-04-06 The Cleveland Clinic Foundation Analysis of microbiome for diagnosis and treating of urinary stone disease
EP4117694A4 (en) * 2020-03-10 2024-06-05 Federation Bio Inc. MICROBIAL CONSORTIUMS FOR DISEASE TREATMENT
WO2022103634A1 (en) 2020-11-16 2022-05-19 Orcosa Inc. Improved use of cannabinoids in the treatment of epilepsy
US11672761B2 (en) 2020-11-16 2023-06-13 Orcosa Inc. Rapidly infusing platform and compositions for therapeutic treatment in humans
EP4329785A1 (en) * 2021-04-30 2024-03-06 Arranta Bio Holdings, LLC Compositions for preserving anaerobic microorganisms and methods of making and using the same

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3030185A1 (de) 1980-08-07 1982-04-08 Kohlbecker, Günther, 3000 Hannover Verfahren zur enzymatischen entfernung von oxalat mittels oxalat-oxidase
DE3204284A1 (de) 1982-02-06 1983-08-18 Kohlbecker, Günther, 3000 Hannover Verfahren zur enzymatischen entfernung von sauerstoff
JPS5968344A (ja) * 1982-10-12 1984-04-18 Agency Of Ind Science & Technol 非対称機能膜及びその製法
US4539118A (en) * 1984-03-23 1985-09-03 Sigma Chemical Company Rapid, accurate method of separation of oxalate from urine and other biological fluids
US5263992A (en) * 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US5427935A (en) * 1987-07-24 1995-06-27 The Regents Of The University Of Michigan Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes
US5206219A (en) * 1991-11-25 1993-04-27 Applied Analytical Industries, Inc. Oral compositions of proteinaceous medicaments
US5286495A (en) * 1992-05-11 1994-02-15 University Of Florida Process for microencapsulating cells
EP0673416A1 (en) * 1992-11-30 1995-09-27 Zeneca Limited Oxalate decarboxylase
FI954911A0 (fi) * 1993-04-16 1995-10-16 Mccormick & Co Inc Kapselointikoostumukset
US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US5554147A (en) * 1994-02-01 1996-09-10 Caphco, Inc. Compositions and devices for controlled release of active ingredients
US5505713A (en) * 1994-04-01 1996-04-09 Minimed Inc. Indwelling catheter with stable enzyme coating
JPH10500019A (ja) 1994-05-18 1998-01-06 ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド ヒトのオキサリル−CoAデカルボキシラーゼ
US6214980B1 (en) * 1994-06-20 2001-04-10 University Of Florida Materials and methods for detection of Oxalobacte formigenes
US6090628A (en) 1994-06-20 2000-07-18 University Of Florida Materials and methods for detection of Oxalobactor formigenes
US5604111A (en) * 1994-06-20 1997-02-18 University Of Florida Research Foundation Method and kit for detection of oxalate
US5912125A (en) * 1994-06-20 1999-06-15 University Of Florida Materials and methods for detection of oxalobacter
US6033719A (en) * 1996-04-25 2000-03-07 Medtronic, Inc. Method for covalent attachment of biomolecules to surfaces of medical devices
SE9603029D0 (sv) 1996-08-20 1996-08-20 Svenska Traeforskningsinst Method for lowering the level of oxalic acid
US6297425B1 (en) * 1997-03-21 2001-10-02 Pioneer Hi-Bred International, Inc. Gene encoding oxalate decarboxylase from aspergillus phoenices
DE69841200D1 (de) * 1997-05-23 2009-11-12 Oxthera Inc Oxalate-abbauende mikroorganismen oder oxalate-abbauende enzyme zur verhütung der oxalate-verwandten krankheiten
US8486389B2 (en) * 1997-05-23 2013-07-16 Oxthera, Inc. Compositions and methods for treating or preventing oxalate-related disease
US20040120941A1 (en) * 1997-05-23 2004-06-24 Allison Milton J. Materials and methods for treating or preventing oxalate-related disease
US6355242B1 (en) * 1997-05-23 2002-03-12 Ixion Biotechnology, Inc. Materials and methods for treating or preventing oxalate-related disease
US6161499A (en) * 1997-07-07 2000-12-19 Cvd Diamond Corporation Apparatus and method for nucleation and deposition of diamond using hot-filament DC plasma
US6080404A (en) * 1997-09-05 2000-06-27 University Of Florida Materials and methods for removal of substances from fluids
US6566407B2 (en) * 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6203797B1 (en) * 1998-01-06 2001-03-20 Stephen C. Perry Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome
MXPA01003197A (es) * 1998-09-28 2004-04-21 Warner Lambert Co Suministro enterico y colonico utilizando capsulas de chpm.
IT1309427B1 (it) 1999-05-28 2002-01-23 Mendes S U R L Composizione dietetica o farmaceutica utile per la prevenzione o iltrattamento dell'iperossaluria e suo uso
HK1046098A1 (zh) 1999-06-07 2002-12-27 南诺斯菲尔股份有限公司 包被颗粒的方法以及所得颗粒
DE10026541A1 (de) * 2000-05-27 2001-11-29 Zeiss Carl Vorrichtung zur präzisen Positionierung eines Bauteils, insbesondere eines optischen Bauteiles
AU2001284427A1 (en) 2000-09-07 2002-03-22 Shingo Tomoda Analog electronic drum set, parts for drum stick, analog electronic drum set andfoot-pedal unit
ATE391509T1 (de) 2000-12-18 2008-04-15 Probio Health Von lactobacillus casei ke01 stamm abgeleitete probiotische verbindungen
US7407668B2 (en) * 2002-01-24 2008-08-05 Boston Scimed, Inc. Medical articles having enzymatic surfaces for localized therapy
US6929940B1 (en) * 2002-08-20 2005-08-16 University Of Florida Research Foundation, Inc. Polynucleotides encoding oxalate decarboxylase from Aspergillus niger and methods of use
US20050100559A1 (en) * 2003-11-07 2005-05-12 The Procter & Gamble Company Stabilized compositions comprising a probiotic
WO2005060937A1 (en) * 2003-12-23 2005-07-07 Chr. Hansen A/S Compressed tablets comprising viable probiotic microorganisms
AU2005339139A1 (en) * 2005-12-14 2007-06-21 Oxthera, Inc. Pharmaceutical compositions and methods for treating or preventing oxalate-related disease

Also Published As

Publication number Publication date
CA2650122C (en) 2015-05-12
HUE034539T2 (en) 2018-02-28
AU2006326016A1 (en) 2007-06-21
ES2628090T3 (es) 2017-08-01
WO2007070052A2 (en) 2007-06-21
ES2426258T8 (es) 2014-11-06
PL1962873T3 (pl) 2014-03-31
EP1962873A4 (en) 2010-08-11
ES2426258T3 (es) 2013-10-22
EP1965816A4 (en) 2012-03-07
EP1962873A2 (en) 2008-09-03
WO2007070677A3 (en) 2008-11-20
US20070178070A1 (en) 2007-08-02
EP1965816B1 (en) 2017-04-05
JP2009519333A (ja) 2009-05-14
AU2006326016B2 (en) 2013-10-10
JP5047190B2 (ja) 2012-10-10
EP1962873B1 (en) 2013-05-29
AU2005339139A1 (en) 2007-06-21
LT1965816T (lt) 2017-07-25
JP5203217B2 (ja) 2013-06-05
CY1118936T1 (el) 2018-01-10
WO2007070677A2 (en) 2007-06-21
DK1962873T3 (da) 2013-08-26
HK1128871A1 (en) 2009-11-13
US20100028422A1 (en) 2010-02-04
CY1114397T1 (el) 2016-08-31
JP2009531275A (ja) 2009-09-03
EP1965816A2 (en) 2008-09-10
AU2005339139A8 (en) 2008-08-07
CA2650122A1 (en) 2007-06-21
SI1962873T1 (sl) 2013-10-30
US8545836B2 (en) 2013-10-01
WO2007070052A3 (en) 2009-04-16
PL1965816T3 (pl) 2017-08-31
PT1962873E (pt) 2013-08-29

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