CA2642020C - Methods and compositions for enhancing engraftment of hematopoietic stem cells - Google Patents
Methods and compositions for enhancing engraftment of hematopoietic stem cells Download PDFInfo
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- CA2642020C CA2642020C CA2642020A CA2642020A CA2642020C CA 2642020 C CA2642020 C CA 2642020C CA 2642020 A CA2642020 A CA 2642020A CA 2642020 A CA2642020 A CA 2642020A CA 2642020 C CA2642020 C CA 2642020C
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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| US77340506P | 2006-02-14 | 2006-02-14 | |
| US60/773,405 | 2006-02-14 | ||
| PCT/US2007/062163 WO2007095594A2 (en) | 2006-02-14 | 2007-02-14 | Methods and compositions for enhancing engraftment of hematopoietic stem cells |
Publications (2)
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| CA2642020A1 CA2642020A1 (en) | 2007-08-23 |
| CA2642020C true CA2642020C (en) | 2014-10-07 |
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| EP (1) | EP1984491B1 (https=) |
| JP (1) | JP5341525B2 (https=) |
| CN (1) | CN101421393B (https=) |
| AU (1) | AU2007214468B2 (https=) |
| CA (1) | CA2642020C (https=) |
| IL (1) | IL193345A (https=) |
| WO (1) | WO2007095594A2 (https=) |
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| CN105168250B (zh) | 2004-10-25 | 2019-02-05 | 塞勒兰特治疗公司 | 增殖骨髓细胞群体的方法及其应用 |
| WO2008137901A2 (en) | 2007-05-06 | 2008-11-13 | Sloan Kettering Institute For Cancer Research | Methods for treating and preventing gi syndrome and graft versus host disease |
| CN102802686A (zh) * | 2009-06-18 | 2012-11-28 | Mc2细胞有限责任公司 | 骨髓胞外基质提取物及其治疗用途 |
| US20130287750A1 (en) * | 2009-10-14 | 2013-10-31 | Cellect Biotechnology Ltd. | Method of selecting stem cells and uses thereof |
| US20130095080A1 (en) | 2010-04-09 | 2013-04-18 | Fred Hutchinson Cancer Reserach Center | Compositions and methods for providing hematopoietic function |
| US20130095079A1 (en) | 2010-04-09 | 2013-04-18 | Fred Hutchinson Cancer Research Center | Compositions and methods for providing hematopoietic function without hla matching |
| US20140205582A1 (en) * | 2011-07-06 | 2014-07-24 | Cellerant Therapeutics, Inc. | Megakaryocyte progenitor cells for production of platelets |
| CA2858069C (en) | 2011-12-08 | 2020-02-11 | Novartis Ag | Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells |
| WO2013130499A1 (en) * | 2012-02-29 | 2013-09-06 | University Of Virginia Patent Foundation | Compositions and methods for cxcr4 signaling and umbilical cord blood stem cell engraftment |
| ES2681050T3 (es) | 2012-04-11 | 2018-09-11 | Acerta Pharma B.V. | Inhibidores de la tirosina quinasa de Bruton para la movilización hematopoyética |
| US10722577B2 (en) * | 2012-05-25 | 2020-07-28 | Sloan Kettering Institute For Cancer Research | Methods for treating GI syndrome and graft versus host disease |
| EP2943566A1 (en) | 2013-01-08 | 2015-11-18 | Fred Hutchinson Cancer Research Center | Compositions and methods for expansion of embryonic hematopoietic stem cells |
| JP2016538253A (ja) * | 2013-10-09 | 2016-12-08 | セレクト バイオセラピューティクス リミテッド | デスリガンドへの移植前曝露による造血前駆細胞の活性化 |
| WO2015057992A1 (en) | 2013-10-16 | 2015-04-23 | Izumi Raquel | Btk inhibitors for hematopoietic mobilization |
| MX389160B (es) | 2013-10-31 | 2025-03-20 | Hutchinson Fred Cancer Res | Células no t efectoras y madre/progenitoras hematopoyéticas modificadas y usos de estas. |
| US10350245B2 (en) | 2015-01-21 | 2019-07-16 | Fred Hutchinson Cancer Research Center | Point-of-care and/or portable platform for gene therapy |
| EP3288570A4 (en) | 2015-04-29 | 2018-11-21 | Fred Hutchinson Cancer Research Center | Modified stem cells and uses thereof |
| WO2016176651A2 (en) | 2015-04-29 | 2016-11-03 | Fred Hutchinson Cancer Research Center | Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof |
| MX2018006828A (es) | 2015-12-04 | 2018-08-09 | Hutchinson Fred Cancer Res | Usos de poblaciones expandidas de celulas madre/progenitoras hematopoyeticas. |
| WO2017203520A1 (en) * | 2016-05-22 | 2017-11-30 | Yeda Research And Development Co. Ltd. | Methods of using pulmonary cells for transplantation and induction of tolerance |
| EP3595683A1 (en) * | 2017-03-15 | 2020-01-22 | Orca Biosystems, Inc. | Compositions and methods for hematopoietic stem cell transplants |
| MX392743B (es) | 2017-04-12 | 2025-03-12 | Magenta Therapeutics Inc | Antagonistas del receptor de hidrocarburo de arilo y sus usos. |
| WO2019089833A1 (en) * | 2017-10-31 | 2019-05-09 | Magenta Therapeutics Inc. | Compositions and methods for hematopoietic stem and progenitor cell transplant therapy |
| US11285177B2 (en) | 2018-01-03 | 2022-03-29 | Globus Medical, Inc. | Allografts containing viable cells and methods thereof |
| EP3849565A4 (en) | 2018-09-12 | 2022-12-28 | Fred Hutchinson Cancer Research Center | REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS |
| EP4476331A2 (en) | 2022-02-07 | 2024-12-18 | Ensoma, Inc. | Inhibitor-resistant mgmt modifications and modification of mgmt-encoding nucleic acids |
| EP4338745A1 (en) * | 2022-09-14 | 2024-03-20 | Technische Universität Dresden | Allogeneic human macrophages for cell therapy |
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| ATE81724T1 (de) | 1987-11-09 | 1992-11-15 | Becton Dickinson Co | Verfahren zur analyse haematopoietischer zellen in einer probe. |
| US6852313B1 (en) | 1989-10-16 | 2005-02-08 | Amgen Inc. | Method of stimulating growth of melanocyte cells by administering stem cell factor |
| US5061620A (en) | 1990-03-30 | 1991-10-29 | Systemix, Inc. | Human hematopoietic stem cell |
| US5840580A (en) | 1990-05-01 | 1998-11-24 | Becton Dickinson And Company | Phenotypic characterization of the hematopoietic stem cell |
| US6326198B1 (en) | 1990-06-14 | 2001-12-04 | Regents Of The University Of Michigan | Methods and compositions for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells |
| US5199942A (en) * | 1991-06-07 | 1993-04-06 | Immunex Corporation | Method for improving autologous transplantation |
| NZ255039A (en) | 1992-07-10 | 1997-03-24 | Univ Pittsburgh | Mammalian hematopoietic facilitatory cells and their use in preventing graft-versus-host disease in bone marrow transplants |
| US6103522A (en) | 1994-07-20 | 2000-08-15 | Fred Hutchinson Cancer Research Center | Human marrow stromal cell lines which sustain hematopoiesis |
| US5925567A (en) | 1995-05-19 | 1999-07-20 | T. Breeders, Inc. | Selective expansion of target cell populations |
| US5877299A (en) | 1995-06-16 | 1999-03-02 | Stemcell Technologies Inc. | Methods for preparing enriched human hematopoietic cell preparations |
| EP0891419A4 (en) | 1996-03-12 | 2000-03-01 | Life Technologies Inc | NUTRIENT ADDITIVE FOR HEMATOPOETIC CELL CULTURES |
| US6335195B1 (en) | 1997-01-28 | 2002-01-01 | Maret Corporation | Method for promoting hematopoietic and mesenchymal cell proliferation and differentiation |
| US6563332B2 (en) | 1997-08-21 | 2003-05-13 | Ibiden Co., Ltd. | Checker head |
| US6908763B1 (en) | 1997-08-22 | 2005-06-21 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian common lymphoid progenitor cell |
| US6558662B2 (en) * | 1997-11-14 | 2003-05-06 | The General Hospital Corporation | Treatment of hematologic disorders |
| ES2252932T3 (es) | 1998-02-05 | 2006-05-16 | Novartis Ag | Poblaciones expandidas y geneticamente modificadas de celulas madre hematopoyeticas humanas. |
| US6464850B1 (en) | 1998-07-31 | 2002-10-15 | Biowhittaker Molecular Applications, Inc. | Method for producing hydrophilic monomers and uses thereof |
| US20030060425A1 (en) | 1998-11-24 | 2003-03-27 | Ahlem Clarence N. | Immune modulation method using steroid compounds |
| CA2369085A1 (en) | 1999-05-14 | 2000-11-23 | City Of Hope | Ex vivo expansion of mammalian hematopoietic stem cells |
| US6761883B2 (en) | 1999-06-29 | 2004-07-13 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian myeloid progenitor cell subsets |
| CA2375974C (en) | 1999-06-29 | 2010-11-02 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian myeloid progenitor cell subsets |
| AU784513B2 (en) | 2000-01-18 | 2006-04-27 | Board Of Trustees Of The Leland Stanford Junior University | Expansion of stem and progenitor cells by beta-catenin |
| ES2378524T3 (es) | 2002-09-13 | 2012-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Célula progenitora de megacariocitos de mamífero |
| AU2003295444A1 (en) | 2002-11-15 | 2004-06-15 | The Board Of Trustees Of The University Of Illinois | Methods for in vitro expansion of hematopoietic stem cells |
| US20040241856A1 (en) | 2003-02-12 | 2004-12-02 | Irm Llc, A Delaware Limited Liability Company | Methods and compositions for modulating stem cells |
| US20050215473A1 (en) | 2003-05-09 | 2005-09-29 | Enrique Alvarez | Prophylactic and therapeutic uses of FGF-20 in radiation protection |
| US20050118147A1 (en) | 2003-11-17 | 2005-06-02 | Il-Hoan Oh | Method of using mesenchymal stromal cells to increase engraftment |
| CN1635113A (zh) * | 2003-12-31 | 2005-07-06 | 中山大学 | 从人间质干细胞制备造血干细胞的方法 |
| CN105168250B (zh) | 2004-10-25 | 2019-02-05 | 塞勒兰特治疗公司 | 增殖骨髓细胞群体的方法及其应用 |
| US7811815B2 (en) * | 2004-11-15 | 2010-10-12 | The Board Of Trustees Of The Leland Stanford Junior University | Therapeutic uses of allogeneic myeloid progenitor cells |
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| EP1984491A2 (en) | 2008-10-29 |
| JP5341525B2 (ja) | 2013-11-13 |
| WO2007095594A2 (en) | 2007-08-23 |
| EP1984491A4 (en) | 2010-03-24 |
| CN101421393A (zh) | 2009-04-29 |
| EP1984491B1 (en) | 2016-12-07 |
| US20070237752A1 (en) | 2007-10-11 |
| WO2007095594A3 (en) | 2008-07-31 |
| IL193345A0 (en) | 2011-08-01 |
| AU2007214468B2 (en) | 2013-04-04 |
| JP2009526784A (ja) | 2009-07-23 |
| IL193345A (en) | 2012-10-31 |
| US8383095B2 (en) | 2013-02-26 |
| CA2642020A1 (en) | 2007-08-23 |
| CN101421393B (zh) | 2013-08-14 |
| AU2007214468A1 (en) | 2007-08-23 |
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