CA2641448A1 - Matrices d'antigenes mimetiques synthetiques immuno-reactives aux auto-anticorps de la polyarthrite rhumatoide - Google Patents

Matrices d'antigenes mimetiques synthetiques immuno-reactives aux auto-anticorps de la polyarthrite rhumatoide Download PDF

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Publication number
CA2641448A1
CA2641448A1 CA 2641448 CA2641448A CA2641448A1 CA 2641448 A1 CA2641448 A1 CA 2641448A1 CA 2641448 CA2641448 CA 2641448 CA 2641448 A CA2641448 A CA 2641448A CA 2641448 A1 CA2641448 A1 CA 2641448A1
Authority
CA
Canada
Prior art keywords
mimetic
sequence
synthetic peptide
immuno
antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2641448
Other languages
English (en)
Inventor
Peter Lea
Mingfu Ling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SQI Diagnostics Systems Inc
Original Assignee
SQI Diagnostics Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SQI Diagnostics Systems Inc filed Critical SQI Diagnostics Systems Inc
Priority to CA 2641448 priority Critical patent/CA2641448A1/fr
Priority to CA2707870A priority patent/CA2707870C/fr
Priority to ES08857631T priority patent/ES2390394T3/es
Priority to JP2010536300A priority patent/JP5611831B2/ja
Priority to US12/734,894 priority patent/US8318440B2/en
Priority to EP08857631A priority patent/EP2229402B1/fr
Priority to AU2008331381A priority patent/AU2008331381B2/en
Priority to PCT/CA2008/002109 priority patent/WO2009070875A1/fr
Priority to CN200880118998.8A priority patent/CN101918432B/zh
Publication of CA2641448A1 publication Critical patent/CA2641448A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders
    • G01N2800/101—Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
    • G01N2800/102—Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
CA 2641448 2007-12-03 2008-10-21 Matrices d'antigenes mimetiques synthetiques immuno-reactives aux auto-anticorps de la polyarthrite rhumatoide Abandoned CA2641448A1 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
CA 2641448 CA2641448A1 (fr) 2008-10-21 2008-10-21 Matrices d'antigenes mimetiques synthetiques immuno-reactives aux auto-anticorps de la polyarthrite rhumatoide
CA2707870A CA2707870C (fr) 2007-12-03 2008-12-03 Peptides synthetiques immunoreactifs avec des auto-anticorps de la polyarthrite rhumatoide
ES08857631T ES2390394T3 (es) 2007-12-03 2008-12-03 Péptidos sintéticos inmunorreactivos con los autoanticuerpos de la artritis reumatoide
JP2010536300A JP5611831B2 (ja) 2007-12-03 2008-12-03 リウマチ性関節炎自己抗体との免疫反応性合成ペプチド
US12/734,894 US8318440B2 (en) 2007-12-03 2008-12-03 Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies
EP08857631A EP2229402B1 (fr) 2007-12-03 2008-12-03 Peptides synthétiques immunoréactifs avec des auto-anticorps de la polyarthrite rhumatoïde
AU2008331381A AU2008331381B2 (en) 2007-12-03 2008-12-03 Synthetic peptides immuno-reactive with rheumatoid arthritis auto-antibodies
PCT/CA2008/002109 WO2009070875A1 (fr) 2007-12-03 2008-12-03 Peptides synthétiques immunoréactifs avec des auto-anticorps de la polyarthrite rhumatoïde
CN200880118998.8A CN101918432B (zh) 2007-12-03 2008-12-03 与类风湿性关节炎自身抗体发生免疫反应的合成肽

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA 2641448 CA2641448A1 (fr) 2008-10-21 2008-10-21 Matrices d'antigenes mimetiques synthetiques immuno-reactives aux auto-anticorps de la polyarthrite rhumatoide

Publications (1)

Publication Number Publication Date
CA2641448A1 true CA2641448A1 (fr) 2010-04-21

Family

ID=42122674

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2641448 Abandoned CA2641448A1 (fr) 2007-12-03 2008-10-21 Matrices d'antigenes mimetiques synthetiques immuno-reactives aux auto-anticorps de la polyarthrite rhumatoide

Country Status (1)

Country Link
CA (1) CA2641448A1 (fr)

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