CA2637052A1 - Dicarbonylic compounds with antibacterial activity - Google Patents

Dicarbonylic compounds with antibacterial activity Download PDF

Info

Publication number
CA2637052A1
CA2637052A1 CA002637052A CA2637052A CA2637052A1 CA 2637052 A1 CA2637052 A1 CA 2637052A1 CA 002637052 A CA002637052 A CA 002637052A CA 2637052 A CA2637052 A CA 2637052A CA 2637052 A1 CA2637052 A1 CA 2637052A1
Authority
CA
Canada
Prior art keywords
isoxazol
nre
fluoro
piperazin
ylaminomethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002637052A
Other languages
English (en)
French (fr)
Inventor
Jose Hidalgo Rodriguez
Juan Lorenzo Catena Ruiz
Isabel Masip Masip
Maria Del Carmen Serra Comas
Oscar Rey Puiggros
Carmen Lagunas Arnal
Carolina Salcedo Roca
Dolors Balsa Lopez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Salvat SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2637052A1 publication Critical patent/CA2637052A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CA002637052A 2006-01-19 2007-01-18 Dicarbonylic compounds with antibacterial activity Abandoned CA2637052A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP200600158 2006-01-19
ES200600158 2006-01-19
PCT/EP2007/050489 WO2007082910A1 (en) 2006-01-19 2007-01-18 Dicarbonylic compounds with antibacterial activity

Publications (1)

Publication Number Publication Date
CA2637052A1 true CA2637052A1 (en) 2007-07-26

Family

ID=37781676

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002637052A Abandoned CA2637052A1 (en) 2006-01-19 2007-01-18 Dicarbonylic compounds with antibacterial activity

Country Status (9)

Country Link
US (1) US20100075984A1 (https=)
EP (1) EP1976837A1 (https=)
JP (1) JP2009523764A (https=)
KR (1) KR20080108977A (https=)
CN (1) CN101405277A (https=)
AU (1) AU2007206889A1 (https=)
BR (1) BRPI0706938A2 (https=)
CA (1) CA2637052A1 (https=)
WO (1) WO2007082910A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5291292B2 (ja) * 2007-02-01 2013-09-18 協同油脂株式会社 金属加工用油剤及び金属加工方法
EP2367820B1 (en) * 2008-11-20 2016-09-21 Panacea Biotec Limited Novel antimicrobial agents
BR112012000657A2 (pt) 2009-06-26 2016-11-16 Panacea Biotec Ltd novos azabicilohexanos
WO2011002067A1 (ja) * 2009-07-02 2011-01-06 武田薬品工業株式会社 複素環化合物およびその用途
CN109503569B (zh) * 2019-01-03 2021-01-15 山东大学 噻唑类衍生物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2180456B1 (es) * 2001-07-20 2004-05-01 Laboratorios S.A.L.V.A.T., S.A. Isoxazoles sustituidos y su utilizacion como antibioticos.
MXPA05001199A (es) * 2002-07-29 2005-05-16 Ranbaxy Lab Ltd Derivados de oxazolidinona como antimicrobianos.
WO2005082892A2 (en) * 2004-02-17 2005-09-09 Dr. Reddy's Laboratories Ltd. Triazole compounds as antibacterial agents and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
US20100075984A1 (en) 2010-03-25
CN101405277A (zh) 2009-04-08
WO2007082910A1 (en) 2007-07-26
EP1976837A1 (en) 2008-10-08
BRPI0706938A2 (pt) 2011-04-12
JP2009523764A (ja) 2009-06-25
KR20080108977A (ko) 2008-12-16
AU2007206889A1 (en) 2007-07-26

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20130118