CA2617600A1 - Reovirus attenue - Google Patents
Reovirus attenue Download PDFInfo
- Publication number
- CA2617600A1 CA2617600A1 CA002617600A CA2617600A CA2617600A1 CA 2617600 A1 CA2617600 A1 CA 2617600A1 CA 002617600 A CA002617600 A CA 002617600A CA 2617600 A CA2617600 A CA 2617600A CA 2617600 A1 CA2617600 A1 CA 2617600A1
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- CA
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- Prior art keywords
- reovirus
- attenuated
- seq
- set forth
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/765—Reovirus; Rotavirus
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12261—Methods of inactivation or attenuation
- C12N2720/12264—Methods of inactivation or attenuation by serial passage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/IB2006/004149 WO2007099401A2 (fr) | 2005-08-01 | 2006-07-31 | Reovirus attenue |
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| CA (1) | CA2617600A1 (fr) |
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| US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
| WO2008110004A1 (fr) | 2007-03-12 | 2008-09-18 | Oncolytics Biotech Inc. | Réovirus ayant des séquences modifiées |
| US10369171B2 (en) * | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
| TW200909581A (en) * | 2007-05-21 | 2009-03-01 | Oncolytics Biotech Inc | Mutant reoviruses and methods of making and using |
| KR20210098202A (ko) * | 2020-01-31 | 2021-08-10 | 바이로큐어 주식회사 | 레오바이러스를 유효성분으로 포함하는 대장염의 예방 또는 치료용 조성물 |
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| KR102654464B1 (ko) * | 2021-09-24 | 2024-04-09 | 바이로큐어 주식회사 | 레오바이러스 기반 신규한 백신플랫폼 및 이의 용도 |
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| US5101068A (en) | 1990-02-16 | 1992-03-31 | Prototek Inc. | Magnesium fluoromalonates |
| US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
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| US7780962B2 (en) * | 1997-10-09 | 2010-08-24 | Wellstat Biologics Corporation | Treatment of neoplasms with RNA viruses |
| US20030044384A1 (en) * | 1997-10-09 | 2003-03-06 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
| AU9603898A (en) | 1997-10-09 | 1999-05-03 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
| CN1477964A (zh) | 1999-04-15 | 2004-02-25 | 应用病毒治疗肿瘤 | |
| CN1289098C (zh) | 1999-09-17 | 2006-12-13 | 威尔斯塔生物公司 | 溶瘤病毒 |
| CA2720361A1 (fr) | 1999-11-12 | 2001-05-25 | Oncolytics Biotech, Inc. | Virus pour le traitement des troubles de la proliferation cellulaire |
| US6605589B1 (en) | 2000-03-31 | 2003-08-12 | Parker Hughes Institute | Cathepsin inhibitors in cancer treatment |
| AR028039A1 (es) * | 2000-05-03 | 2003-04-23 | Oncolytics Biotech Inc | Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas |
| AR028040A1 (es) * | 2000-05-03 | 2003-04-23 | Oncolytics Biotech Inc | Remocion de virus de celulas neoplasticas a partir de composiciones celulares mixtas |
| US7306902B2 (en) | 2002-06-28 | 2007-12-11 | Oncolyties Biotech Inc. | Oncolytic viruses as phenotyping agents for neoplasms |
| JP5208343B2 (ja) * | 2000-06-26 | 2013-06-12 | ウェルスタット バイオロジクス コーポレイション | ウイルスを用いる細胞の浄化 |
| TWI289158B (en) | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
| ATE472733T1 (de) | 2000-11-09 | 2010-07-15 | Oncolytics Biotech Inc | Verfahren zur beurteilung von zellulären proliferativen erkrankungen |
| WO2002040042A2 (fr) | 2000-11-20 | 2002-05-23 | Oncolytics Biotech, Inc. | Procede d'apport optimal d'un virus a une masse de tumeur solide |
| WO2002043647A2 (fr) | 2000-12-01 | 2002-06-06 | University Of Ottawa | Virus oncolytique |
| AR035227A1 (es) * | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
| EP1370643A1 (fr) | 2001-03-16 | 2003-12-17 | Oncolytics Biotech, Inc. | Methode pour extraire un virus d'une culture de cellules |
| US7122182B2 (en) * | 2001-05-11 | 2006-10-17 | Wellstat Biologics Corporation | Oncolytic virus therapy |
| US20040115170A1 (en) * | 2001-11-30 | 2004-06-17 | Brown Earl Garnet | Oncolytic virus |
| CA2374388C (fr) | 2002-02-28 | 2005-07-12 | Matthew C. Coffey | L'utilisation de ribozymes pour la detection d'agents adventifs |
| EP1605053A1 (fr) | 2002-03-26 | 2005-12-14 | Oncolytics Biotech Inc. | Utilisation d'adenovirus mutés dans les gênes VA en vue du traitement du cancer |
| WO2003093463A1 (fr) | 2002-04-30 | 2003-11-13 | Oncolytics Biotech Inc. | Procede ameliore de purification de virus |
| BR0309825A (pt) | 2002-05-09 | 2005-03-01 | Oncolytics Biotech Inc | Método e composição farmacêutica para reduzir a dor em um mamìfero que sofra de um neoplasma |
| JP4546823B2 (ja) | 2002-05-10 | 2010-09-22 | オンコリティクス バイオテク，インコーポレーテッド | 腫瘍崩壊性ウイルスによる放射線療法に対する新生物細胞の感作 |
| US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
| CA2411397C (fr) | 2002-11-07 | 2013-01-22 | Oncolytics Biotech Inc. | Reovirus pour le traitement de troubles de la proliferation cellulaire induits par ral |
| WO2004066947A2 (fr) | 2003-01-28 | 2004-08-12 | Shanghai Sunway Biotech Co., Ltd. | Traitement pour cancers primaires et metastatiques |
| CA2422245A1 (fr) | 2003-03-14 | 2004-09-14 | Oncolytics Biotech Inc. | Methodes de traitement de troubles de la proliferation cellulaire |
| WO2005002607A2 (fr) | 2003-07-07 | 2005-01-13 | Oncolytics Biotech Inc. | Virus oncolytiques pour le traitement de neoplasmes a pp2a et rac activees |
| CA2434995A1 (fr) | 2003-07-07 | 2005-01-07 | Oncolytics Biotech Inc. | Virus oncolytiques pour le traitement de tumeurs caracterisees par une activite de la pp2a ou de rac |
| CA2435967A1 (fr) | 2003-07-25 | 2005-01-25 | Oncolytics Biotech, Inc. | Reovirus pour le traitement de tumeurs malignes lymphoides |
| CA2436196A1 (fr) | 2003-07-25 | 2005-01-25 | Oncolytics Biotech Inc. | Virus oncolytique pour eliminer les cellules de tumeurs malignes lymphoides presentes dans des melanges de cellules |
| CA2575591A1 (fr) * | 2003-08-08 | 2005-02-17 | Yuji Shino | Composition pharmaceutique pour le traitement de cancers |
| US20050214266A1 (en) * | 2004-03-12 | 2005-09-29 | Oncolytics Biotech Inc. | Combination of transplantation and oncolytic virus treatment |
| US7901921B2 (en) * | 2004-10-22 | 2011-03-08 | Oncolytics Biotech Inc. | Viral purification methods |
| US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
| US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
| AU2016308696B2 (en) | 2015-08-17 | 2021-01-07 | Aker Biomarine Antarctic As | Methods for improving health of farmed fish |
-
2006
- 2006-07-31 WO PCT/IB2006/004149 patent/WO2007099401A2/fr active Application Filing
- 2006-07-31 US US11/997,537 patent/US10260049B2/en active Active
- 2006-07-31 EP EP06849494A patent/EP1917351A4/fr not_active Withdrawn
- 2006-07-31 CA CA002617600A patent/CA2617600A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20090214479A1 (en) | 2009-08-27 |
| WO2007099401A2 (fr) | 2007-09-07 |
| EP1917351A2 (fr) | 2008-05-07 |
| EP1917351A4 (fr) | 2009-12-16 |
| US10260049B2 (en) | 2019-04-16 |
| WO2007099401A3 (fr) | 2008-03-13 |
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