CA2617600A1 - Reovirus attenue - Google Patents
Reovirus attenue Download PDFInfo
- Publication number
- CA2617600A1 CA2617600A1 CA002617600A CA2617600A CA2617600A1 CA 2617600 A1 CA2617600 A1 CA 2617600A1 CA 002617600 A CA002617600 A CA 002617600A CA 2617600 A CA2617600 A CA 2617600A CA 2617600 A1 CA2617600 A1 CA 2617600A1
- Authority
- CA
- Canada
- Prior art keywords
- reovirus
- attenuated
- seq
- set forth
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/765—Reovirus; Rotavirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
- C12N2720/00011—Details
- C12N2720/12011—Reoviridae
- C12N2720/12211—Orthoreovirus, e.g. mammalian orthoreovirus
- C12N2720/12261—Methods of inactivation or attenuation
- C12N2720/12264—Methods of inactivation or attenuation by serial passage
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70460405P | 2005-08-01 | 2005-08-01 | |
US60/704,604 | 2005-08-01 | ||
PCT/IB2006/004149 WO2007099401A2 (fr) | 2005-08-01 | 2006-07-31 | Reovirus attenue |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2617600A1 true CA2617600A1 (fr) | 2007-09-07 |
Family
ID=38459397
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002617600A Abandoned CA2617600A1 (fr) | 2005-08-01 | 2006-07-31 | Reovirus attenue |
Country Status (4)
Country | Link |
---|---|
US (1) | US10260049B2 (fr) |
EP (1) | EP1917351A4 (fr) |
CA (1) | CA2617600A1 (fr) |
WO (1) | WO2007099401A2 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
JP5577103B2 (ja) | 2007-03-12 | 2014-08-20 | オンコリティクス バイオテク,インコーポレーテッド | 改変配列を有するレオウイルス |
US10369171B2 (en) * | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
TW200909581A (en) * | 2007-05-21 | 2009-03-01 | Oncolytics Biotech Inc | Mutant reoviruses and methods of making and using |
KR20210098202A (ko) * | 2020-01-31 | 2021-08-10 | 바이로큐어 주식회사 | 레오바이러스를 유효성분으로 포함하는 대장염의 예방 또는 치료용 조성물 |
US20240041959A1 (en) * | 2020-12-22 | 2024-02-08 | Virocure, Inc. | Novel modified reovirus and use thereof |
KR102654464B1 (ko) * | 2021-09-24 | 2024-04-09 | 바이로큐어 주식회사 | 레오바이러스 기반 신규한 백신플랫폼 및 이의 용도 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5101068A (en) | 1990-02-16 | 1992-03-31 | Prototek Inc. | Magnesium fluoromalonates |
US5210272A (en) | 1990-02-16 | 1993-05-11 | Prototek, Inc. | Process for forming a fluoromethyl ketone |
US6565831B1 (en) * | 1999-02-24 | 2003-05-20 | Oncolytics Biotech Inc. | Methods for preventing reovirus recognition for the treatment of cellular proliferative disorders |
US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
US6136307A (en) * | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
CA2305269C (fr) | 1997-10-09 | 2012-07-03 | Pro-Virus, Inc. | Traitement de neoplasmes par des virus |
US7780962B2 (en) * | 1997-10-09 | 2010-08-24 | Wellstat Biologics Corporation | Treatment of neoplasms with RNA viruses |
US20030044384A1 (en) * | 1997-10-09 | 2003-03-06 | Pro-Virus, Inc. | Treatment of neoplasms with viruses |
EP1390046A4 (fr) | 1999-04-15 | 2005-04-20 | Wellstat Biologics Corp | Traitement de neoplasmes avec des virus |
CA2386920C (fr) | 1999-09-17 | 2012-01-24 | Pro-Virus, Inc. | Virus oncolytique |
CA2388807C (fr) * | 1999-11-12 | 2013-08-06 | Matthew C. Coffey | Virus pour le traitement des troubles de la proliferation cellulaire |
US6605589B1 (en) | 2000-03-31 | 2003-08-12 | Parker Hughes Institute | Cathepsin inhibitors in cancer treatment |
AR028040A1 (es) | 2000-05-03 | 2003-04-23 | Oncolytics Biotech Inc | Remocion de virus de celulas neoplasticas a partir de composiciones celulares mixtas |
AR028039A1 (es) | 2000-05-03 | 2003-04-23 | Oncolytics Biotech Inc | Remocion de reovirus de celulas neoplasticas intermediadas por ras a partir de composiciones celulares mixtas |
US7306902B2 (en) | 2002-06-28 | 2007-12-11 | Oncolyties Biotech Inc. | Oncolytic viruses as phenotyping agents for neoplasms |
CN1250711C (zh) * | 2000-06-26 | 2006-04-12 | 威尔斯达特生物制剂公司 | 用病毒清除细胞 |
TWI289158B (en) | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
DE60142485D1 (de) | 2000-11-09 | 2010-08-12 | Oncolytics Biotech Inc | Verfahren zur Beurteilung von zellulären proliferativen Erkrankungen |
EP1335737A2 (fr) | 2000-11-20 | 2003-08-20 | Oncolytics Biotech, Inc. | Procede d'apport optimal d'un virus a une masse de tumeur solide |
CA2430495A1 (fr) | 2000-12-01 | 2002-06-06 | University Of Ottawa | Virus oncolytique |
AR035227A1 (es) * | 2001-02-20 | 2004-05-05 | Oncolytics Biotech Inc | Uso de un agente quimioterapeutico para la manufactura de un medicamento para la sensibilizacion de celulas neoplasicas resistentes a agentes quimioterapeuticos con reovirus |
ES2500645T3 (es) * | 2001-03-16 | 2014-09-30 | Oncolytics Biotech Inc. | Método para extracción de virus de un cultivo celular |
JP4916641B2 (ja) | 2001-05-11 | 2012-04-18 | ウェルスタット バイオロジクス コーポレイション | 腫瘍崩壊性ウイルス治療 |
US20040115170A1 (en) * | 2001-11-30 | 2004-06-17 | Brown Earl Garnet | Oncolytic virus |
CA2374388C (fr) | 2002-02-28 | 2005-07-12 | Matthew C. Coffey | L'utilisation de ribozymes pour la detection d'agents adventifs |
CA2478616C (fr) | 2002-03-26 | 2012-05-29 | Oncolytics Biotech Inc. | Utilisation d'adenovirus mutes dans les genes va en vue du traitement du cancer |
EP1501921B2 (fr) | 2002-04-30 | 2012-07-25 | Oncolytics Biotech Inc. | Procede ameliore de purification de virus |
DE60322885D1 (de) | 2002-05-09 | 2008-09-25 | Oncolytics Biotech Inc | Methode zur schmerzbekämpfung mit onkolytischen viren |
DK1505993T3 (da) | 2002-05-10 | 2012-05-21 | Oncolytics Biotech Inc | Sensibilisering af neoplastiske celler for stråleterapi med onkolytiske vira |
US7163678B2 (en) * | 2002-11-07 | 2007-01-16 | Oncolytics Biotech Inc. | Reovirus for the treatment of ral-mediated cellular proliferative disorders |
CA2411397C (fr) | 2002-11-07 | 2013-01-22 | Oncolytics Biotech Inc. | Reovirus pour le traitement de troubles de la proliferation cellulaire induits par ral |
JP2006519784A (ja) * | 2003-01-28 | 2006-08-31 | シャンハイ、サンウエイ、バイアテク、カムパニ、リミティド | 原発癌および転移癌に対する治療(a2)温熱療法と腫瘍溶解の同時治療(a3) |
CA2422245A1 (fr) | 2003-03-14 | 2004-09-14 | Oncolytics Biotech Inc. | Methodes de traitement de troubles de la proliferation cellulaire |
CA2434995A1 (fr) | 2003-07-07 | 2005-01-07 | Oncolytics Biotech Inc. | Virus oncolytiques pour le traitement de tumeurs caracterisees par une activite de la pp2a ou de rac |
WO2005002607A2 (fr) | 2003-07-07 | 2005-01-13 | Oncolytics Biotech Inc. | Virus oncolytiques pour le traitement de neoplasmes a pp2a et rac activees |
CA2436196A1 (fr) | 2003-07-25 | 2005-01-25 | Oncolytics Biotech Inc. | Virus oncolytique pour eliminer les cellules de tumeurs malignes lymphoides presentes dans des melanges de cellules |
CA2435967A1 (fr) * | 2003-07-25 | 2005-01-25 | Oncolytics Biotech, Inc. | Reovirus pour le traitement de tumeurs malignes lymphoides |
WO2005014017A1 (fr) | 2003-08-08 | 2005-02-17 | Yuji Shino | Composition medicinale pour traiter le cancer |
US20050214266A1 (en) * | 2004-03-12 | 2005-09-29 | Oncolytics Biotech Inc. | Combination of transplantation and oncolytic virus treatment |
US7901921B2 (en) * | 2004-10-22 | 2011-03-08 | Oncolytics Biotech Inc. | Viral purification methods |
US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
US10653725B2 (en) | 2015-08-17 | 2020-05-19 | Aker Biomarine Antarctic As | Methods for improving health of farmed fish |
-
2006
- 2006-07-31 EP EP06849494A patent/EP1917351A4/fr not_active Withdrawn
- 2006-07-31 WO PCT/IB2006/004149 patent/WO2007099401A2/fr active Application Filing
- 2006-07-31 US US11/997,537 patent/US10260049B2/en active Active
- 2006-07-31 CA CA002617600A patent/CA2617600A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2007099401A3 (fr) | 2008-03-13 |
WO2007099401A2 (fr) | 2007-09-07 |
EP1917351A4 (fr) | 2009-12-16 |
US10260049B2 (en) | 2019-04-16 |
EP1917351A2 (fr) | 2008-05-07 |
US20090214479A1 (en) | 2009-08-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |