CA2609891A1 - Cores and microcapsules suitable for parenteral administration as well as process for their manufacture - Google Patents
Cores and microcapsules suitable for parenteral administration as well as process for their manufacture Download PDFInfo
- Publication number
- CA2609891A1 CA2609891A1 CA002609891A CA2609891A CA2609891A1 CA 2609891 A1 CA2609891 A1 CA 2609891A1 CA 002609891 A CA002609891 A CA 002609891A CA 2609891 A CA2609891 A CA 2609891A CA 2609891 A1 CA2609891 A1 CA 2609891A1
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- CA
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- Prior art keywords
- cores
- polymer
- active substance
- release
- biologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05011516.1 | 2005-05-27 | ||
| EP05011516 | 2005-05-27 | ||
| EP05028165.8 | 2005-12-22 | ||
| EP05028165A EP1726299A3 (en) | 2005-05-27 | 2005-12-22 | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
| PCT/EP2006/004940 WO2006125620A2 (en) | 2005-05-27 | 2006-05-24 | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2609891A1 true CA2609891A1 (en) | 2006-11-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002609891A Abandoned CA2609891A1 (en) | 2005-05-27 | 2006-05-24 | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP1726299A3 (enExample) |
| JP (1) | JP5080453B2 (enExample) |
| AT (1) | ATE424190T1 (enExample) |
| CA (1) | CA2609891A1 (enExample) |
| DE (1) | DE602006005491D1 (enExample) |
| DK (1) | DK1906928T3 (enExample) |
| WO (1) | WO2006125620A2 (enExample) |
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| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| GB0707612D0 (en) | 2007-04-19 | 2007-05-30 | Stratosphere Pharma Ab | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
| BRPI0811784A2 (pt) | 2007-05-23 | 2011-05-10 | Allergan Inc | colÁgeno reticulado e uso do mesmo |
| BRPI0811777A2 (pt) * | 2007-05-23 | 2019-09-24 | Allergan Inc | partículas de ácido hialurõnico revestidas |
| US8318695B2 (en) | 2007-07-30 | 2012-11-27 | Allergan, Inc. | Tunably crosslinked polysaccharide compositions |
| US8697044B2 (en) | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| CN101896204B (zh) | 2007-11-16 | 2015-05-20 | 爱力根有限公司 | 用于治疗紫癜的组合物及方法 |
| US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
| US8394784B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
| US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
| AU2009288118B2 (en) | 2008-09-02 | 2014-12-11 | Allergan, Inc. | Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| EP2544652A2 (en) | 2010-03-12 | 2013-01-16 | Allergan Industrie SAS | A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition. |
| CA2794254C (en) | 2010-03-22 | 2018-09-04 | Allergan, Inc. | Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation |
| US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
| US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
| US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| JP6009550B2 (ja) | 2011-06-03 | 2016-10-19 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 抗酸化物質を含む皮膚充填剤組成物 |
| US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
| US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
| WO2016051219A1 (en) | 2014-09-30 | 2016-04-07 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
| ES2774051T3 (es) | 2015-02-13 | 2020-07-16 | Allergan Ind Sas | Implantes para esculpir, aumentar o corregir características faciales, tales como la barbilla |
| WO2025137151A2 (en) | 2023-12-18 | 2025-06-26 | The Johns Hopkins University | Dendrimer compositions for the treatment of atherosclerosis, obesity, and metabolic syndromes |
| CN118146569B (zh) * | 2024-01-24 | 2024-11-22 | 中国海洋大学 | 透明质酸-青蒿琥酯-聚精氨酸纳米粒、制备方法及应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| WO1992016191A1 (en) * | 1991-03-25 | 1992-10-01 | Fujisawa Pharmaceutical Co., Ltd. | Long-acting pharmaceutical preparation |
| DE4201179A1 (de) * | 1992-01-17 | 1993-07-22 | Alfatec Pharma Gmbh | Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung |
| KR100201352B1 (ko) * | 1995-03-16 | 1999-06-15 | 성재갑 | 단일주사 백신 제형 |
| SE505146C2 (sv) | 1995-10-19 | 1997-06-30 | Biogram Ab | Partiklar för fördröjd frisättning |
| EP0994700A4 (en) * | 1997-07-18 | 2000-10-18 | Bayer Ag | METHODS FOR REMOVING SOLVENT RESIDUES FROM COMPOSITIONS FOR THE NASAL ADMINISTRATION OF ACTIVE SUBSTANCES |
| SE9903236D0 (sv) | 1999-09-10 | 1999-09-10 | Astra Ab | Method to obtain microparticles |
| DE60040012D1 (de) * | 1999-11-12 | 2008-10-02 | Fibrogen Inc | Rekombinantes gelatin in impstoffen |
| JP2004510730A (ja) * | 2000-10-06 | 2004-04-08 | ヤゴテック アーゲー | 非経口的投与可能な制御放出微粒子調製物 |
| ATE397020T1 (de) | 2000-10-06 | 2008-06-15 | Pacira Pharmaceuticals Inc | Pharmazeutisch verwendbare stärke und deren herstellungsverfahren |
| JP2004510724A (ja) | 2000-10-06 | 2004-04-08 | ヤゴテック アーゲー | 分子量の低下した澱粉からなる微粒子中に埋め込まれた免疫学的活性物質を含むワクチン組成物 |
-
2005
- 2005-12-22 EP EP05028165A patent/EP1726299A3/en not_active Withdrawn
-
2006
- 2006-05-24 DK DK06743048T patent/DK1906928T3/da active
- 2006-05-24 JP JP2008512759A patent/JP5080453B2/ja not_active Expired - Fee Related
- 2006-05-24 CA CA002609891A patent/CA2609891A1/en not_active Abandoned
- 2006-05-24 EP EP06743048A patent/EP1906928B1/en not_active Not-in-force
- 2006-05-24 WO PCT/EP2006/004940 patent/WO2006125620A2/en not_active Ceased
- 2006-05-24 AT AT06743048T patent/ATE424190T1/de not_active IP Right Cessation
- 2006-05-24 DE DE602006005491T patent/DE602006005491D1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008542220A (ja) | 2008-11-27 |
| WO2006125620A3 (en) | 2007-08-02 |
| JP5080453B2 (ja) | 2012-11-21 |
| EP1726299A2 (en) | 2006-11-29 |
| ATE424190T1 (de) | 2009-03-15 |
| EP1726299A3 (en) | 2007-04-18 |
| EP1906928A2 (en) | 2008-04-09 |
| DE602006005491D1 (de) | 2009-04-16 |
| DK1906928T3 (da) | 2009-04-20 |
| EP1906928B1 (en) | 2009-03-04 |
| WO2006125620A2 (en) | 2006-11-30 |
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