CA2609891A1 - Cores and microcapsules suitable for parenteral administration as well as process for their manufacture - Google Patents
Cores and microcapsules suitable for parenteral administration as well as process for their manufacture Download PDFInfo
- Publication number
- CA2609891A1 CA2609891A1 CA002609891A CA2609891A CA2609891A1 CA 2609891 A1 CA2609891 A1 CA 2609891A1 CA 002609891 A CA002609891 A CA 002609891A CA 2609891 A CA2609891 A CA 2609891A CA 2609891 A1 CA2609891 A1 CA 2609891A1
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- CA
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- Prior art keywords
- cores
- polymer
- active substance
- release
- biologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05011516.1 | 2005-05-27 | ||
| EP05011516 | 2005-05-27 | ||
| EP05028165.8 | 2005-12-22 | ||
| EP05028165A EP1726299A3 (en) | 2005-05-27 | 2005-12-22 | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
| PCT/EP2006/004940 WO2006125620A2 (en) | 2005-05-27 | 2006-05-24 | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2609891A1 true CA2609891A1 (en) | 2006-11-30 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002609891A Abandoned CA2609891A1 (en) | 2005-05-27 | 2006-05-24 | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
Country Status (7)
| Country | Link |
|---|---|
| EP (2) | EP1726299A3 (cg-RX-API-DMAC10.html) |
| JP (1) | JP5080453B2 (cg-RX-API-DMAC10.html) |
| AT (1) | ATE424190T1 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2609891A1 (cg-RX-API-DMAC10.html) |
| DE (1) | DE602006005491D1 (cg-RX-API-DMAC10.html) |
| DK (1) | DK1906928T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2006125620A2 (cg-RX-API-DMAC10.html) |
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| FR2861734B1 (fr) | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| GB0707612D0 (en) | 2007-04-19 | 2007-05-30 | Stratosphere Pharma Ab | Cores and microcapsules suitable for parenteral administration as well as process for their manufacture |
| EP2162158A2 (en) | 2007-05-23 | 2010-03-17 | Allergan, Inc. | Coated hyaluronic acid particles |
| CA2687990A1 (en) | 2007-05-23 | 2008-12-04 | Allergan, Inc. | Cross-linked collagen and uses thereof |
| US8318695B2 (en) | 2007-07-30 | 2012-11-27 | Allergan, Inc. | Tunably crosslinked polysaccharide compositions |
| US8697044B2 (en) | 2007-10-09 | 2014-04-15 | Allergan, Inc. | Crossed-linked hyaluronic acid and collagen and uses thereof |
| PT2818184T (pt) | 2007-11-16 | 2019-01-28 | Aclaris Therapeutics Inc | Composições e métodos para o tratamento de púrpura |
| US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
| US8394784B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
| US8357795B2 (en) | 2008-08-04 | 2013-01-22 | Allergan, Inc. | Hyaluronic acid-based gels including lidocaine |
| CA2735173C (en) | 2008-09-02 | 2017-01-10 | Tautona Group Lp | Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof |
| US9114188B2 (en) | 2010-01-13 | 2015-08-25 | Allergan, Industrie, S.A.S. | Stable hydrogel compositions including additives |
| US20110172180A1 (en) | 2010-01-13 | 2011-07-14 | Allergan Industrie. Sas | Heat stable hyaluronic acid compositions for dermatological use |
| US8586562B2 (en) | 2010-03-12 | 2013-11-19 | Allergan Industrie, Sas | Fluid compositions for improving skin conditions |
| EP4062950A1 (en) | 2010-03-22 | 2022-09-28 | Allergan, Inc. | Syringe comprising dermal filler for soft tissue augmentation |
| US8883139B2 (en) | 2010-08-19 | 2014-11-11 | Allergan Inc. | Compositions and soft tissue replacement methods |
| US9005605B2 (en) | 2010-08-19 | 2015-04-14 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8697057B2 (en) | 2010-08-19 | 2014-04-15 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| US8889123B2 (en) | 2010-08-19 | 2014-11-18 | Allergan, Inc. | Compositions and soft tissue replacement methods |
| RU2624239C2 (ru) | 2011-06-03 | 2017-07-03 | Аллерган, Инк. | Составы кожного наполнителя, включая антиоксиданты |
| US20130096081A1 (en) | 2011-06-03 | 2013-04-18 | Allergan, Inc. | Dermal filler compositions |
| US9408797B2 (en) | 2011-06-03 | 2016-08-09 | Allergan, Inc. | Dermal filler compositions for fine line treatment |
| US9393263B2 (en) | 2011-06-03 | 2016-07-19 | Allergan, Inc. | Dermal filler compositions including antioxidants |
| US9662422B2 (en) | 2011-09-06 | 2017-05-30 | Allergan, Inc. | Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation |
| US20130244943A1 (en) | 2011-09-06 | 2013-09-19 | Allergan, Inc. | Hyaluronic acid-collagen matrices for dermal filling and volumizing applications |
| WO2016051219A1 (en) | 2014-09-30 | 2016-04-07 | Allergan Industrie, Sas | Stable hydrogel compositions including additives |
| WO2016128783A1 (en) | 2015-02-09 | 2016-08-18 | Allergan Industrie Sas | Compositions and methods for improving skin appearance |
| RU2715234C2 (ru) | 2015-02-13 | 2020-02-26 | Аллерган Эндюстри, Сас | Имплантаты для моделирования, увеличения или коррекции частей лица, например подбородка |
| IL330156A (en) | 2023-12-18 | 2026-08-01 | The Johns Hopkins Univ | Dendrimer compositions for the treatment of atherosclerosis, obesity and metabolic syndromes |
| CN118146569B (zh) * | 2024-01-24 | 2024-11-22 | 中国海洋大学 | 透明质酸-青蒿琥酯-聚精氨酸纳米粒、制备方法及应用 |
| WO2025265116A1 (en) | 2024-06-21 | 2025-12-26 | Georgia State University Research Foundation, Inc. | Nanobodies to henipavirus and uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
| WO1992016191A1 (en) * | 1991-03-25 | 1992-10-01 | Fujisawa Pharmaceutical Co., Ltd. | Long-acting pharmaceutical preparation |
| DE4201179A1 (de) * | 1992-01-17 | 1993-07-22 | Alfatec Pharma Gmbh | Wirkstoff(e) enthaltendes granulat oder pellet mit einem geruest aus hydrophilen makromolekuelen und verfahren zu seiner herstellung |
| KR100201352B1 (ko) * | 1995-03-16 | 1999-06-15 | 성재갑 | 단일주사 백신 제형 |
| SE505146C2 (sv) | 1995-10-19 | 1997-06-30 | Biogram Ab | Partiklar för fördröjd frisättning |
| EP0994700A4 (en) * | 1997-07-18 | 2000-10-18 | Bayer Ag | METHODS FOR REMOVING SOLVENT RESIDUES FROM COMPOSITIONS FOR THE NASAL ADMINISTRATION OF ACTIVE SUBSTANCES |
| SE9903236D0 (sv) | 1999-09-10 | 1999-09-10 | Astra Ab | Method to obtain microparticles |
| AU1591701A (en) * | 1999-11-12 | 2001-06-06 | Fibrogen, Inc. | Recombinant gelatins |
| CA2424896A1 (en) * | 2000-10-06 | 2002-04-11 | Jagotec Ag | A controlled-release, parenterally administrable microparticle preparation |
| JP2004510723A (ja) | 2000-10-06 | 2004-04-08 | ヤゴテック アーゲー | 低下した分子量のアミロペクチンをベースとする精製された澱粉を含む制御放出投与のための生物分解性微粒子 |
| AU2001294460A1 (en) | 2000-10-06 | 2002-04-15 | Jagotec Ab | Starch |
-
2005
- 2005-12-22 EP EP05028165A patent/EP1726299A3/en not_active Withdrawn
-
2006
- 2006-05-24 AT AT06743048T patent/ATE424190T1/de not_active IP Right Cessation
- 2006-05-24 DE DE602006005491T patent/DE602006005491D1/de not_active Expired - Lifetime
- 2006-05-24 WO PCT/EP2006/004940 patent/WO2006125620A2/en not_active Ceased
- 2006-05-24 EP EP06743048A patent/EP1906928B1/en not_active Expired - Lifetime
- 2006-05-24 JP JP2008512759A patent/JP5080453B2/ja not_active Expired - Fee Related
- 2006-05-24 DK DK06743048T patent/DK1906928T3/da active
- 2006-05-24 CA CA002609891A patent/CA2609891A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1726299A2 (en) | 2006-11-29 |
| EP1906928B1 (en) | 2009-03-04 |
| DE602006005491D1 (de) | 2009-04-16 |
| JP2008542220A (ja) | 2008-11-27 |
| WO2006125620A2 (en) | 2006-11-30 |
| JP5080453B2 (ja) | 2012-11-21 |
| ATE424190T1 (de) | 2009-03-15 |
| WO2006125620A3 (en) | 2007-08-02 |
| DK1906928T3 (da) | 2009-04-20 |
| EP1726299A3 (en) | 2007-04-18 |
| EP1906928A2 (en) | 2008-04-09 |
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