CA2603850A1 - Analogues b de polymyxine destines a la detoxification lps - Google Patents

Analogues b de polymyxine destines a la detoxification lps Download PDF

Info

Publication number
CA2603850A1
CA2603850A1 CA002603850A CA2603850A CA2603850A1 CA 2603850 A1 CA2603850 A1 CA 2603850A1 CA 002603850 A CA002603850 A CA 002603850A CA 2603850 A CA2603850 A CA 2603850A CA 2603850 A1 CA2603850 A1 CA 2603850A1
Authority
CA
Canada
Prior art keywords
lps
peptide
leu
lys
cys2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002603850A
Other languages
English (en)
Inventor
Massimo Porro
Tino Krell
Noelle Mistretta
Monique Moreau
Alessandro Rustici
Massimo Velucchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biosynth SRL
Sanofi Pasteur Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05300270A external-priority patent/EP1712559A1/fr
Application filed by Individual filed Critical Individual
Publication of CA2603850A1 publication Critical patent/CA2603850A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
CA002603850A 2005-04-11 2006-04-10 Analogues b de polymyxine destines a la detoxification lps Abandoned CA2603850A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP05300270.5 2005-04-11
EP05300270A EP1712559A1 (fr) 2005-04-11 2005-04-11 Analogues de Polymixin B pour détoxification de LPS
EP05300319.0 2005-04-26
EP05300319 2005-04-26
PCT/EP2006/003237 WO2006108586A2 (fr) 2005-04-11 2006-04-10 Analogues b de polymyxine destines a la detoxification lps

Publications (1)

Publication Number Publication Date
CA2603850A1 true CA2603850A1 (fr) 2006-10-19

Family

ID=36968822

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002603850A Abandoned CA2603850A1 (fr) 2005-04-11 2006-04-10 Analogues b de polymyxine destines a la detoxification lps

Country Status (11)

Country Link
EP (1) EP1871787A2 (fr)
JP (1) JP2008537749A (fr)
KR (1) KR20070118646A (fr)
AU (1) AU2006233634A1 (fr)
BR (1) BRPI0610701A2 (fr)
CA (1) CA2603850A1 (fr)
IL (1) IL186322A0 (fr)
MX (1) MX2007012457A (fr)
NO (1) NO20075753L (fr)
NZ (1) NZ561374A (fr)
WO (1) WO2006108586A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090123499A1 (en) 2006-06-12 2009-05-14 Nathalie Devos Vaccine
WO2010130898A2 (fr) 2009-05-14 2010-11-18 Sanofi Pasteur Vaccin meningocoque a base de lipooligosaccharide (los) provenant de souches modifiees de neisseria meningitidis d'immunotype l6
CA2761916A1 (fr) 2009-05-14 2010-11-18 Sanofi Pasteur Procede pour adjuver le lipopolysaccharide (lps) des bacteries a gram-negatif
TWI548746B (zh) * 2009-08-06 2016-09-11 英特威特國際股份有限公司 防備豬胸膜肺炎之疫苗及製備該疫苗之方法
NZ765453A (en) * 2017-12-22 2024-03-22 Hanmi Pharmaceutical Co Ltd Therapeutic enzyme fusion protein having novel structure and use thereof
CN115298197A (zh) * 2020-03-20 2022-11-04 Hlb科学株式会社 用于去除脂多糖的组合物和试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371186A (en) * 1991-02-11 1994-12-06 Biosynth S.R.L. Synthetic peptides for detoxification of bacterial endotoxins and for the prevention and treatment of septic shock
AU2002368447A1 (en) * 2002-12-06 2004-06-30 Biosynth S.R.L. Broad-spectrum lps based vaccines of unencapsulated strains ofhaemophilus influenzae and other pathogenic species of gram-negative bacteria

Also Published As

Publication number Publication date
NO20075753L (no) 2007-11-09
WO2006108586A3 (fr) 2006-12-14
AU2006233634A1 (en) 2006-10-19
WO2006108586A2 (fr) 2006-10-19
EP1871787A2 (fr) 2008-01-02
KR20070118646A (ko) 2007-12-17
JP2008537749A (ja) 2008-09-25
MX2007012457A (es) 2007-12-10
NZ561374A (en) 2009-02-28
IL186322A0 (en) 2008-01-20
BRPI0610701A2 (pt) 2010-07-20

Similar Documents

Publication Publication Date Title
Kabanova et al. Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate
KR101573648B1 (ko) 합성 베타-1,6 글루코사민 올리고당에 관한 방법 및 조성물
KR100593466B1 (ko) 다당류-펩타이드접합체
US20010048929A1 (en) Novel multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
JP2008523142A (ja) ペプチドグリカンを含有する複合糖質ワクチン
CA2603850A1 (fr) Analogues b de polymyxine destines a la detoxification lps
US11246919B2 (en) Glycoconjugate vaccines comprising basic units of a molecular construct expressing built-in multiple epitopes for the formulation of a broad-spectrum vaccine against infections due to enteropathogenic bacteria
US7588765B2 (en) Polysaccharide and glycoconjugate vaccines
US6951652B2 (en) Vaccine for prevention of gram-negative bacterial infections and endotoxin related diseases
US11420993B2 (en) Semi-synthetic meningococcal conjugate vaccine
KR20030096369A (ko) 저분자량 하이알루론산과 폴리펩티드 독소의 면역원성접합체
EP1712559A1 (fr) Analogues de Polymixin B pour détoxification de LPS
US7507718B2 (en) Polymyxin B analogs for LPS detoxification
WO2004052394A1 (fr) Vaccins a base de lps a large spectre de souches non encapsulees de haemophilus influenzae et d'autres especes pathogenes de bacteries gram-negatives
Velucchi et al. A model of Neisseria meningitidis vaccine based on LPS micelles detoxified by synthetic antiendotoxin peptides
CN112603996A (zh) 一种脂磷壁酸疫苗制剂及其应用
JP2023089973A (ja) ワクチン組成物
Velucchi et al. A model of Meisseria meningitidis
ITUB20159533A1 (it) Immunoadiuvanti vaccinali
MXPA98007617A (es) Conjugados de polisacaridos peptidos

Legal Events

Date Code Title Description
FZDE Discontinued