CA2603389C - Identifying statistically linear data - Google Patents

Identifying statistically linear data Download PDF

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Publication number
CA2603389C
CA2603389C CA2603389A CA2603389A CA2603389C CA 2603389 C CA2603389 C CA 2603389C CA 2603389 A CA2603389 A CA 2603389A CA 2603389 A CA2603389 A CA 2603389A CA 2603389 C CA2603389 C CA 2603389C
Authority
CA
Canada
Prior art keywords
data set
measure
calculating
smoothed
original data
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2603389A
Other languages
English (en)
French (fr)
Other versions
CA2603389A1 (en
Inventor
Jeffrey Lerner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bio Rad Laboratories Inc
Original Assignee
Bio Rad Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/432,856 external-priority patent/US7647187B2/en
Application filed by Bio Rad Laboratories Inc filed Critical Bio Rad Laboratories Inc
Publication of CA2603389A1 publication Critical patent/CA2603389A1/en
Application granted granted Critical
Publication of CA2603389C publication Critical patent/CA2603389C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F18/00—Pattern recognition
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F2218/00—Aspects of pattern recognition specially adapted for signal processing
    • G06F2218/08—Feature extraction
    • G06F2218/10—Feature extraction by analysing the shape of a waveform, e.g. extracting parameters relating to peaks

Landscapes

  • Engineering & Computer Science (AREA)
  • Theoretical Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Evolutionary Biology (AREA)
  • Evolutionary Computation (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Artificial Intelligence (AREA)
  • Complex Calculations (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Radar Systems Or Details Thereof (AREA)
CA2603389A 2005-05-13 2006-05-12 Identifying statistically linear data Expired - Fee Related CA2603389C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US68118205P 2005-05-13 2005-05-13
US60/681,182 2005-05-13
US11/432,856 US7647187B2 (en) 2005-05-13 2006-05-11 Identifying statistically linear data
US11/432,856 2006-05-11
PCT/US2006/018549 WO2006124673A2 (en) 2005-05-13 2006-05-12 Identifying statistically linear data

Publications (2)

Publication Number Publication Date
CA2603389A1 CA2603389A1 (en) 2006-11-23
CA2603389C true CA2603389C (en) 2012-07-10

Family

ID=37431939

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2603389A Expired - Fee Related CA2603389C (en) 2005-05-13 2006-05-12 Identifying statistically linear data

Country Status (6)

Country Link
EP (1) EP1880334A4 (enrdf_load_stackoverflow)
JP (1) JP5091122B2 (enrdf_load_stackoverflow)
CN (1) CN101292245B (enrdf_load_stackoverflow)
AU (1) AU2006247597B2 (enrdf_load_stackoverflow)
CA (1) CA2603389C (enrdf_load_stackoverflow)
WO (1) WO2006124673A2 (enrdf_load_stackoverflow)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090119020A1 (en) * 2007-09-25 2009-05-07 Roche Molecular Systems, Inc. Pcr elbow determination using quadratic test for curvature analysis of a double sigmoid
JPWO2009054474A1 (ja) * 2007-10-26 2011-03-10 凸版印刷株式会社 アレル判定装置及び方法、ならびに、コンピュータプログラム
CA2736243A1 (en) * 2008-09-09 2010-03-18 Bio-Rad Laboratories, Inc. Multi-stage, regression-based pcr analysis system
US8219366B2 (en) * 2009-08-26 2012-07-10 Roche Molecular Sytems, Inc. Determination of elbow values for PCR for parabolic shaped curves
JP5379044B2 (ja) * 2010-02-25 2013-12-25 株式会社日立ハイテクノロジーズ 自動分析装置
US10176293B2 (en) 2012-10-02 2019-01-08 Roche Molecular Systems, Inc. Universal method to determine real-time PCR cycle threshold values

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2139070C (en) * 1994-12-23 2010-03-30 Burton W. Blais Method for enhancing detection ability of nucleic acid assays employing polymerase chain reaction
US6175602B1 (en) * 1998-05-27 2001-01-16 Telefonaktiebolaget Lm Ericsson (Publ) Signal noise reduction by spectral subtraction using linear convolution and casual filtering
WO2002034948A2 (en) * 2000-10-25 2002-05-02 City Of Hope Candidate region mismatch scanning for genotyping and mutation detection
US7228237B2 (en) * 2002-02-07 2007-06-05 Applera Corporation Automatic threshold setting and baseline determination for real-time PCR
US20050069904A1 (en) * 2003-09-29 2005-03-31 Stuart Peirson Analysis of real-time PCR data

Also Published As

Publication number Publication date
JP5091122B2 (ja) 2012-12-05
WO2006124673A3 (en) 2008-04-17
JP2008546048A (ja) 2008-12-18
EP1880334A4 (en) 2010-01-20
WO2006124673A2 (en) 2006-11-23
CN101292245B (zh) 2013-04-17
EP1880334A2 (en) 2008-01-23
AU2006247597A1 (en) 2006-11-23
CA2603389A1 (en) 2006-11-23
CN101292245A (zh) 2008-10-22
AU2006247597B2 (en) 2010-02-11

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Effective date: 20160512