CA2599525C - Hiv vif - Google Patents

Hiv vif Download PDF

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Publication number
CA2599525C
CA2599525C CA2599525A CA2599525A CA2599525C CA 2599525 C CA2599525 C CA 2599525C CA 2599525 A CA2599525 A CA 2599525A CA 2599525 A CA2599525 A CA 2599525A CA 2599525 C CA2599525 C CA 2599525C
Authority
CA
Canada
Prior art keywords
vif
polynucleotide
vector
retroviral
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2599525A
Other languages
English (en)
French (fr)
Other versions
CA2599525A1 (en
Inventor
Chiara Bovolenta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Biologics SpA
Original Assignee
MolMed SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0504770A external-priority patent/GB0504770D0/en
Priority claimed from GB0510888A external-priority patent/GB0510888D0/en
Application filed by MolMed SpA filed Critical MolMed SpA
Publication of CA2599525A1 publication Critical patent/CA2599525A1/en
Application granted granted Critical
Publication of CA2599525C publication Critical patent/CA2599525C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus human T-cell leukaemia-lymphoma virus
    • C07K14/155Lentiviridae, e.g. human immunodeficiency virus [HIV], visna-maedi virus or equine infectious anaemia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/15011Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15041Use of virus, viral particle or viral elements as a vector
    • C12N2740/15043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2599525A 2005-03-08 2006-03-07 Hiv vif Expired - Fee Related CA2599525C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0504770.9 2005-03-08
GB0504770A GB0504770D0 (en) 2005-03-08 2005-03-08 HIV Vif
GB0510888A GB0510888D0 (en) 2005-05-26 2005-05-26 Hiv vif
GB0510888.1 2005-05-26
PCT/IB2006/001519 WO2006111866A2 (en) 2005-03-08 2006-03-07 Hiv vif mutants

Publications (2)

Publication Number Publication Date
CA2599525A1 CA2599525A1 (en) 2006-10-26
CA2599525C true CA2599525C (en) 2015-05-26

Family

ID=37115522

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2599525A Expired - Fee Related CA2599525C (en) 2005-03-08 2006-03-07 Hiv vif

Country Status (9)

Country Link
US (1) US8912152B2 (enExample)
EP (1) EP1883649B1 (enExample)
JP (1) JP5324912B2 (enExample)
KR (1) KR101411272B1 (enExample)
AT (1) ATE533777T1 (enExample)
AU (1) AU2006238617B2 (enExample)
CA (1) CA2599525C (enExample)
ES (1) ES2377829T3 (enExample)
WO (1) WO2006111866A2 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011015379A1 (en) 2009-08-05 2011-02-10 Nexigen Gbmh Human hcv-interacting proteins and methods of use
CU23896B1 (es) * 2010-04-01 2013-05-31 Ct De Ingeniería Genética Y Biotecnología Método para inhibir la replicación del vih en células de mamíferos
KR102458904B1 (ko) * 2020-06-19 2022-11-01 숙명여자대학교산학협력단 신규의 bmpr2 유전자 기능획득 돌연변이체 및 이의 용도

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7198784B2 (en) * 1996-10-17 2007-04-03 Oxford Biomedica (Uk) Limited Retroviral vectors
WO2005024422A2 (en) * 2003-05-23 2005-03-17 Oregon Health & Science University Methods for identifying inhibitors

Also Published As

Publication number Publication date
AU2006238617A1 (en) 2006-10-26
JP5324912B2 (ja) 2013-10-23
WO2006111866A2 (en) 2006-10-26
EP1883649A2 (en) 2008-02-06
US8912152B2 (en) 2014-12-16
KR20070118624A (ko) 2007-12-17
CA2599525A1 (en) 2006-10-26
KR101411272B1 (ko) 2014-07-03
JP2008532510A (ja) 2008-08-21
ATE533777T1 (de) 2011-12-15
ES2377829T3 (es) 2012-04-02
AU2006238617B2 (en) 2012-08-02
EP1883649B1 (en) 2011-11-16
US20080286248A1 (en) 2008-11-20
WO2006111866A3 (en) 2007-04-12

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MKLA Lapsed

Effective date: 20190307