CA2596959A1 - New uses of dinucleotide polyphosphate derivatives - Google Patents
New uses of dinucleotide polyphosphate derivatives Download PDFInfo
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- CA2596959A1 CA2596959A1 CA002596959A CA2596959A CA2596959A1 CA 2596959 A1 CA2596959 A1 CA 2596959A1 CA 002596959 A CA002596959 A CA 002596959A CA 2596959 A CA2596959 A CA 2596959A CA 2596959 A1 CA2596959 A1 CA 2596959A1
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0502250.4A GB0502250D0 (en) | 2005-02-03 | 2005-02-03 | Use |
| GB0502250.4 | 2005-02-03 | ||
| PCT/GB2006/000343 WO2006082397A1 (en) | 2005-02-03 | 2006-02-01 | New uses of dinucleotide polyphosphate derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2596959A1 true CA2596959A1 (en) | 2006-08-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002596959A Abandoned CA2596959A1 (en) | 2005-02-03 | 2006-02-01 | New uses of dinucleotide polyphosphate derivatives |
Country Status (8)
| Country | Link |
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| US (1) | US20080319184A1 (enExample) |
| EP (1) | EP1846004A1 (enExample) |
| JP (1) | JP2008528665A (enExample) |
| CN (1) | CN101180066A (enExample) |
| AU (1) | AU2006210715A1 (enExample) |
| CA (1) | CA2596959A1 (enExample) |
| GB (1) | GB0502250D0 (enExample) |
| WO (1) | WO2006082397A1 (enExample) |
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|---|---|---|---|---|
| GB201209244D0 (en) * | 2012-05-25 | 2012-07-04 | Globalacorn Ltd | Compositions |
| GB201320962D0 (en) * | 2013-11-27 | 2014-01-08 | Globalacorn Ltd | Compositions |
| GB201320959D0 (en) * | 2013-11-27 | 2014-01-08 | Globalacorn Ltd | Compositions |
| KR102504764B1 (ko) * | 2017-06-21 | 2023-03-02 | 주식회사 종근당 | 디뉴클레오사이드 폴리포스페이트 화합물의 제조방법 |
| WO2021123388A1 (en) * | 2019-12-20 | 2021-06-24 | Nuvamid Sa | Novel nicotinamide di-nucleotide derivatives and use thereof |
Family Cites Families (12)
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| US5837861A (en) * | 1997-02-10 | 1998-11-17 | Inspire Pharmaceuticals, Inc. | Dinucleotides and their use as modulators of mucociliary clearance and ciliary beat frequency |
| US5681823A (en) * | 1996-05-02 | 1997-10-28 | Prp Inc. | P1, P4 -dithio-P2 -P3 -monochloromethylene 5', 5'"-diadenosine P1, P4 -tetraphosphate as antithrombotic agent |
| US6696425B2 (en) * | 1997-02-06 | 2004-02-24 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with purinergic receptor agonists |
| ES2264197T3 (es) * | 1997-02-06 | 2006-12-16 | Inspire Pharmaceuticals, Inc. | Dinucleotidos y sus usos. |
| US6596725B2 (en) * | 1997-02-10 | 2003-07-22 | Inspire Pharmaceuticals, Inc. | Use of certain dinucleotides to stimulate removal of fluid in retinal detachment and retinal edema |
| GB9711848D0 (en) * | 1997-06-06 | 1997-08-06 | William Harvey Research Limite | Treatment and prophylaxis of infraction |
| WO1999003480A1 (en) * | 1997-07-17 | 1999-01-28 | William Harvey Research Limited | Use of adenosine tri- or tetra-phosphates and their analogues for the treatment of cerebral infarction |
| US7084126B1 (en) * | 2000-05-01 | 2006-08-01 | Healthpartners Research Foundation | Methods and compositions for enhancing cellular function through protection of tissue components |
| US6555675B2 (en) * | 2000-08-21 | 2003-04-29 | Inspire Pharmaceuticals, Inc. | Dinucleoside polyphosphate compositions and their therapuetic use as purinergic receptor agonists |
| GB2394419B (en) * | 2001-06-25 | 2005-09-07 | Inspire Pharmaceuticals Inc | Joint lubrication with p2y purinergic receptor agonists |
| CN1612739A (zh) * | 2001-11-06 | 2005-05-04 | 印斯拜尔药品股份有限公司 | 治疗或预防炎性疾病的方法 |
| US7203743B2 (en) * | 2001-12-28 | 2007-04-10 | Nortel Networks Limited | Hierarchical tree-based protection scheme for mesh networks |
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2005
- 2005-02-03 GB GBGB0502250.4A patent/GB0502250D0/en not_active Ceased
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2006
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- 2006-02-01 JP JP2007553689A patent/JP2008528665A/ja active Pending
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- 2006-02-01 US US11/883,661 patent/US20080319184A1/en not_active Abandoned
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- 2006-02-01 EP EP06704231A patent/EP1846004A1/en not_active Withdrawn
- 2006-02-01 CA CA002596959A patent/CA2596959A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| GB0502250D0 (en) | 2005-03-09 |
| WO2006082397A1 (en) | 2006-08-10 |
| AU2006210715A1 (en) | 2006-08-10 |
| CN101180066A (zh) | 2008-05-14 |
| EP1846004A1 (en) | 2007-10-24 |
| JP2008528665A (ja) | 2008-07-31 |
| US20080319184A1 (en) | 2008-12-25 |
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