CA2588106A1 - Anticorps a domaine unique et anticorps a chaines lourdes ciblant le recepteur du facteur de croissance epidermique et utilisations connexes - Google Patents
Anticorps a domaine unique et anticorps a chaines lourdes ciblant le recepteur du facteur de croissance epidermique et utilisations connexes Download PDFInfo
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- CA2588106A1 CA2588106A1 CA002588106A CA2588106A CA2588106A1 CA 2588106 A1 CA2588106 A1 CA 2588106A1 CA 002588106 A CA002588106 A CA 002588106A CA 2588106 A CA2588106 A CA 2588106A CA 2588106 A1 CA2588106 A1 CA 2588106A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6881—Cluster-antibody conjugates, i.e. the modifying agent consists of a plurality of antibodies covalently linked to each other or of different antigen-binding fragments covalently linked to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/22—Immunoglobulins specific features characterized by taxonomic origin from camelids, e.g. camel, llama or dromedary
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002588106A CA2588106A1 (fr) | 2007-05-18 | 2007-05-18 | Anticorps a domaine unique et anticorps a chaines lourdes ciblant le recepteur du facteur de croissance epidermique et utilisations connexes |
| PCT/CA2008/000966 WO2008141449A1 (fr) | 2007-05-18 | 2008-05-20 | Anticorps à domaine unique et anticorps à chaîne lourde contre egfr et leurs utilisations |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002588106A CA2588106A1 (fr) | 2007-05-18 | 2007-05-18 | Anticorps a domaine unique et anticorps a chaines lourdes ciblant le recepteur du facteur de croissance epidermique et utilisations connexes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2588106A1 true CA2588106A1 (fr) | 2008-11-18 |
Family
ID=40030393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002588106A Abandoned CA2588106A1 (fr) | 2007-05-18 | 2007-05-18 | Anticorps a domaine unique et anticorps a chaines lourdes ciblant le recepteur du facteur de croissance epidermique et utilisations connexes |
Country Status (2)
| Country | Link |
|---|---|
| CA (1) | CA2588106A1 (fr) |
| WO (1) | WO2008141449A1 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2011325833C1 (en) | 2010-11-05 | 2017-07-13 | Zymeworks Bc Inc. | Stable heterodimeric antibody design with mutations in the Fc domain |
| CA2854233C (fr) | 2011-11-04 | 2020-05-12 | Zymeworks Inc. | Structure d'anticorps heterodimerique stable comprenant des mutations dans le domaine fc |
| TWI443108B (zh) | 2011-12-28 | 2014-07-01 | Ind Tech Res Inst | 抗人類表皮生長因子受體抗體及其應用 |
| US9914785B2 (en) | 2012-11-28 | 2018-03-13 | Zymeworks Inc. | Engineered immunoglobulin heavy chain-light chain pairs and uses thereof |
| CA2930307A1 (fr) * | 2013-11-13 | 2015-05-21 | Zymeworks Inc. | Produits de recombinaison liant un antigene monovalent et ciblant l'egfr et/ou l'her2 et leurs utilisations |
| US9546211B2 (en) * | 2014-10-23 | 2017-01-17 | Singh Molecular Medicine, Llc | Single domain antibodies directed against TNF-alpha |
| NO344051B1 (en) * | 2017-05-04 | 2019-08-26 | Patogen As | Novel virus in Fish and Method for detection |
| US20240101686A1 (en) * | 2020-12-09 | 2024-03-28 | Simcere Zaiming Pharmaceutical Co., Ltd. | Anti-egfr nanobody and use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE485307T1 (de) * | 2003-11-07 | 2010-11-15 | Ablynx Nv | Camelidae schwere ketten antikörper vhhs gegen epidermalen wachstumfaktor rezeptor (egfr) und ihre verwendung |
| EP1934259A2 (fr) * | 2005-10-11 | 2008-06-25 | Ablynx N.V. | Nanobodies et polypeptides diriges contre l'egfr et l'igf-ir |
-
2007
- 2007-05-18 CA CA002588106A patent/CA2588106A1/fr not_active Abandoned
-
2008
- 2008-05-20 WO PCT/CA2008/000966 patent/WO2008141449A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008141449A1 (fr) | 2008-11-27 |
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