CA2584078A1 - Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation - Google Patents

Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation Download PDF

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Publication number
CA2584078A1
CA2584078A1 CA002584078A CA2584078A CA2584078A1 CA 2584078 A1 CA2584078 A1 CA 2584078A1 CA 002584078 A CA002584078 A CA 002584078A CA 2584078 A CA2584078 A CA 2584078A CA 2584078 A1 CA2584078 A1 CA 2584078A1
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CA
Canada
Prior art keywords
zcytor21
seq
amino acid
polypeptide
acid residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002584078A
Other languages
English (en)
French (fr)
Inventor
Zeren Gao
Rolf E. Kuestner
Mark W. Appleby
Katherine E. Lewis
Patricia A. Mckernan
Shannon L. Okada
David W. Taft
Joseph L. Kuijper
Stephen R. Jaspers
Steven D. Levin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2584078A1 publication Critical patent/CA2584078A1/en
Abandoned legal-status Critical Current

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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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    • A61P31/04Antibacterial agents
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    • A61P39/02Antidotes
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    • AHUMAN NECESSITIES
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    • A61P9/08Vasodilators for multiple indications
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    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Microbiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Mycology (AREA)
CA002584078A 2004-10-18 2005-10-18 Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation Abandoned CA2584078A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US61965104P 2004-10-18 2004-10-18
US60/619,651 2004-10-18
US62220704P 2004-10-25 2004-10-25
US60/622,207 2004-10-25
PCT/US2005/037332 WO2006044840A2 (en) 2004-10-18 2005-10-18 Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation

Publications (1)

Publication Number Publication Date
CA2584078A1 true CA2584078A1 (en) 2006-04-27

Family

ID=36090952

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002584078A Abandoned CA2584078A1 (en) 2004-10-18 2005-10-18 Soluble zcytor21, anti-zcytor21 antibodies and binding partners and methods of using in inflammation

Country Status (12)

Country Link
US (3) US20060142192A1 (enExample)
EP (1) EP1802657A2 (enExample)
JP (1) JP2008516985A (enExample)
KR (1) KR20070084330A (enExample)
AU (1) AU2005295421A1 (enExample)
BR (1) BRPI0516603A (enExample)
CA (1) CA2584078A1 (enExample)
EA (1) EA200700823A1 (enExample)
IL (1) IL182186A0 (enExample)
MX (1) MX2007004597A (enExample)
NO (1) NO20072514L (enExample)
WO (1) WO2006044840A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods
US20060142192A1 (en) * 2004-10-18 2006-06-29 Zeren Gao Soluble ZcytoR21, anti-ZcytoR21 antibodies and binding partners and methods of using in inflammation
CA2624763A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
CA2666842A1 (en) * 2006-10-18 2008-04-24 Zymogenetics, Inc. Il-17c antagonists and methods of using the same
HUE037087T2 (hu) * 2011-10-19 2018-08-28 Morphosys Ag IL17C antagonistái gyulladásos rendellenességek kezelésére
RU2018114657A (ru) * 2015-10-05 2019-11-07 МорфоСис АГ Антагонисты IL-17C для лечения и/или предупреждения атопического дерматита
ES2877376T3 (es) 2016-02-19 2021-11-16 Morphosys Ag Anticuerpos para IL-17C
IL309179A (en) * 2021-06-10 2024-02-01 Janssen Biotech Inc Nucleic acid coding for KLK2-GPI fusion protein, recombinant cells and their uses

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0817847T4 (da) * 1995-03-23 2009-10-05 Immunex Corp IL-17-receptor
US20020177188A1 (en) * 1998-05-15 2002-11-28 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US6569645B2 (en) * 1999-05-14 2003-05-27 Genentech, Inc. IL-17 homologous polypeptides and therapeutic uses thereof
US6579520B2 (en) * 1998-05-15 2003-06-17 Genentech, Inc. IL-17 related mammalian cytokine polypeptides (IL-17E)
US20040197306A1 (en) * 2000-05-24 2004-10-07 Gorman Daniel M. Mammalian receptor proteins; related reagents and methods
MXPA02011617A (es) * 2000-05-24 2003-03-10 Schering Corp Proteinas de mamiferos receptoras, reactivosy metodos relacionados.
US20030096969A1 (en) * 2000-06-02 2003-05-22 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
JP2005508615A (ja) * 2001-07-09 2005-04-07 ザイモジェネティクス,インコーポレイティド ヒトサイトカイン受容体
US20060142192A1 (en) * 2004-10-18 2006-06-29 Zeren Gao Soluble ZcytoR21, anti-ZcytoR21 antibodies and binding partners and methods of using in inflammation
CA2624763A1 (en) * 2005-10-18 2007-04-26 Zymogenetics, Inc. Il-17c antagonists and methods of using the same

Also Published As

Publication number Publication date
KR20070084330A (ko) 2007-08-24
AU2005295421A1 (en) 2006-04-27
WO2006044840A3 (en) 2006-10-26
IL182186A0 (en) 2007-07-24
MX2007004597A (es) 2007-06-22
BRPI0516603A (pt) 2008-09-16
EP1802657A2 (en) 2007-07-04
WO2006044840A2 (en) 2006-04-27
US20060142192A1 (en) 2006-06-29
WO2006044840A8 (en) 2006-07-06
US20070049525A1 (en) 2007-03-01
JP2008516985A (ja) 2008-05-22
NO20072514L (no) 2007-07-17
EA200700823A1 (ru) 2008-02-28
US20070049524A1 (en) 2007-03-01

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Effective date: 20101018