CA2583821A1 - Process for the de-enrichment of enantiomerically enriched substrates - Google Patents

Process for the de-enrichment of enantiomerically enriched substrates Download PDF

Info

Publication number
CA2583821A1
CA2583821A1 CA002583821A CA2583821A CA2583821A1 CA 2583821 A1 CA2583821 A1 CA 2583821A1 CA 002583821 A CA002583821 A CA 002583821A CA 2583821 A CA2583821 A CA 2583821A CA 2583821 A1 CA2583821 A1 CA 2583821A1
Authority
CA
Canada
Prior art keywords
optionally substituted
group
hydrocarbyl
carbon
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002583821A
Other languages
English (en)
French (fr)
Inventor
Andrew John Blacker
Matthew John Stirling
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Piramal Healthcare UK Ltd
Original Assignee
Avecia Pharmaceuticals Limited
Andrew John Blacker
Matthew John Stirling
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avecia Pharmaceuticals Limited, Andrew John Blacker, Matthew John Stirling filed Critical Avecia Pharmaceuticals Limited
Publication of CA2583821A1 publication Critical patent/CA2583821A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B55/00—Racemisation; Complete or partial inversion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B31/00—Reduction in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C07C29/145—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA002583821A 2004-10-29 2005-10-27 Process for the de-enrichment of enantiomerically enriched substrates Abandoned CA2583821A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0424000.8 2004-10-29
GBGB0424000.8A GB0424000D0 (en) 2004-10-29 2004-10-29 Process
PCT/GB2005/004179 WO2006046062A1 (en) 2004-10-29 2005-10-27 Process for the de-enrichment of enantiomerically enriched substrates

Publications (1)

Publication Number Publication Date
CA2583821A1 true CA2583821A1 (en) 2006-05-04

Family

ID=33515740

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002583821A Abandoned CA2583821A1 (en) 2004-10-29 2005-10-27 Process for the de-enrichment of enantiomerically enriched substrates

Country Status (11)

Country Link
EP (1) EP1809586A1 (ja)
JP (1) JP2008517990A (ja)
KR (1) KR20070068428A (ja)
CN (1) CN101052604A (ja)
BR (1) BRPI0517243A (ja)
CA (1) CA2583821A1 (ja)
GB (1) GB0424000D0 (ja)
IL (1) IL182589A0 (ja)
MX (1) MX2007005169A (ja)
WO (1) WO2006046062A1 (ja)
ZA (1) ZA200702979B (ja)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008056768A1 (fr) * 2006-11-10 2008-05-15 Wako Pure Chemical Industries, Ltd. Catalyseur de métaux porteur de composites carbone/éthylénédiamine et son procédé de production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476964A (en) * 1994-11-21 1995-12-19 Uop Continuous racemization of benzylic alcohols, ethers, and esters by solid acid catalyst
EP1300381B1 (en) * 1995-12-06 2006-03-08 Japan Science and Technology Agency Process for preparing optically active alcohols
CA2165125A1 (en) * 1995-12-13 1997-06-14 David W. House Continuous process for racemization of benzylic alcohols, ethers, and esters by solid acid catalyst
GB0029356D0 (en) * 2000-12-01 2001-01-17 Avecia Ltd Transfer hydrogenation
DE10062729A1 (de) * 2000-12-15 2002-06-20 Basf Ag Verfahren zur Racemisierung von optisch aktiven Aminen
DE10133783A1 (de) * 2001-07-16 2003-02-06 Degussa Verfahren zur Racemisierung von Alkoholen

Also Published As

Publication number Publication date
IL182589A0 (en) 2007-07-24
KR20070068428A (ko) 2007-06-29
GB0424000D0 (en) 2004-12-01
EP1809586A1 (en) 2007-07-25
ZA200702979B (en) 2008-08-27
MX2007005169A (es) 2007-07-04
JP2008517990A (ja) 2008-05-29
WO2006046062A1 (en) 2006-05-04
CN101052604A (zh) 2007-10-10
BRPI0517243A (pt) 2008-10-07

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Legal Events

Date Code Title Description
FZDE Discontinued