CA2583297A1 - Phenyl derivatives and methods of use - Google Patents
Phenyl derivatives and methods of use Download PDFInfo
- Publication number
- CA2583297A1 CA2583297A1 CA002583297A CA2583297A CA2583297A1 CA 2583297 A1 CA2583297 A1 CA 2583297A1 CA 002583297 A CA002583297 A CA 002583297A CA 2583297 A CA2583297 A CA 2583297A CA 2583297 A1 CA2583297 A1 CA 2583297A1
- Authority
- CA
- Canada
- Prior art keywords
- dimethyl
- methyl
- oxo
- morpholin
- hexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C07D213/82—Amides; Imides in position 3
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- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- Engineering & Computer Science (AREA)
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- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Neurosurgery (AREA)
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- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
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- Urology & Nephrology (AREA)
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- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61602404P | 2004-10-05 | 2004-10-05 | |
| US60/616,024 | 2004-10-05 | ||
| US11/242,318 | 2005-10-03 | ||
| US11/242,318 US7671052B2 (en) | 2004-10-05 | 2005-10-03 | Phenyl derivatives and methods of use |
| PCT/US2005/035677 WO2006041841A1 (en) | 2004-10-05 | 2005-10-04 | Phenyl derivatives and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2583297A1 true CA2583297A1 (en) | 2006-04-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002583297A Abandoned CA2583297A1 (en) | 2004-10-05 | 2005-10-04 | Phenyl derivatives and methods of use |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7671052B2 (https=) |
| EP (1) | EP1817277A4 (https=) |
| JP (1) | JP2008515897A (https=) |
| CN (1) | CN101035758B (https=) |
| AU (1) | AU2005294459A1 (https=) |
| BR (1) | BRPI0516544A (https=) |
| CA (1) | CA2583297A1 (https=) |
| MX (1) | MX2007003826A (https=) |
| WO (1) | WO2006041841A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0427954D0 (en) * | 2004-12-21 | 2005-01-26 | Univ London | Modulator |
| CA2654026A1 (en) * | 2006-06-08 | 2007-12-13 | Neurokey A/S | Use of cannabinoid receptor agonists as hypothermia inducing drugs for the treatment of ischemia |
| WO2008109027A2 (en) * | 2007-03-02 | 2008-09-12 | University Of Tennessee Research Foundation, The | Tri-aryl/heteroaroaromatic cannabinoids and use thereof |
| CN101815513B (zh) * | 2007-08-07 | 2012-11-14 | 斯泰伦博斯大学 | 含有对乙酰氨基苯酚的眼用制剂 |
| EP2211619A1 (en) * | 2007-10-18 | 2010-08-04 | Merck Sharp & Dohme Corp. | Substituted 1,2,4-oxadiazoles and analogs thereof as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases |
| WO2009140078A1 (en) * | 2008-05-16 | 2009-11-19 | The Procter & Gamble Company | Treatment of lower urinary tract dysfunction with cb2-receptor-selective agonists |
| KR20110130489A (ko) * | 2009-03-23 | 2011-12-05 | 스미또모 가가꾸 가부시끼가이샤 | 시클로프로판카르복실산에스테르의 제조 방법 |
| US9855225B2 (en) * | 2011-08-18 | 2018-01-02 | Temple University Office Of Technology Transfer | Cannabinoid receptor treatments |
| CN103288684B (zh) * | 2013-05-03 | 2014-12-10 | 西安交通大学 | 一种具有抗肿瘤活性的联苯脲化合物及其制备方法 |
| US9585867B2 (en) | 2015-08-06 | 2017-03-07 | Charles Everett Ankner | Cannabinod formulation for the sedation of a human or animal |
| US12364668B2 (en) | 2017-11-15 | 2025-07-22 | The Regents Of The University Of California | Treatment of opioid use disorder, opioid withdrawal symptoms, and chronic pain |
| US12409131B2 (en) | 2019-10-03 | 2025-09-09 | Pike Therapeutics Usa, Inc. | Transdermal delivery of dronabinol |
| CN114650809A (zh) | 2019-10-03 | 2022-06-21 | 斯塔顿治疗公司 | 屈大麻酚的透皮递送 |
| CA3155176A1 (en) | 2019-10-11 | 2021-04-15 | Pike Therapeutics, Inc., 1219014 B.C. Ltd. | Transdermal compositions comprising cannabidiol (cbd) for use in the treatment of seizure disorders |
| US12016829B2 (en) | 2019-10-11 | 2024-06-25 | Pike Therapeutics Inc. | Pharmaceutical composition and method for treating seizure disorders |
| CA3155181A1 (en) | 2019-10-14 | 2021-04-22 | Pike Therapeutics, Inc., 1219014 B.C. Ltd. | Transdermal delivery of cannabidiol |
| US12268699B2 (en) | 2019-10-14 | 2025-04-08 | Pike Therapeutics Inc. | Transdermal delivery of tetrahydrocannabinol |
| US12121617B2 (en) | 2019-10-14 | 2024-10-22 | Pike Therapeutics Inc. | Transdermal delivery of cannabidiol |
| EP3838967A1 (en) * | 2019-12-16 | 2021-06-23 | Spago Nanomedical AB | Immobilization of phenolic compounds |
| JP7687721B2 (ja) * | 2020-12-25 | 2025-06-03 | エムティックスバイオ カンパニ- リミテッド | 新規なアミノアルカン酸にビフェニル基を導入した誘導体化合物およびそれを含む抗炎症用組成物 |
| EP4276092A4 (en) * | 2021-01-06 | 2025-01-01 | Chugai Seiyaku Kabushiki Kaisha | Compound library |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3663608A (en) * | 1969-12-10 | 1972-05-16 | Bristol Myers Co | 1-phenyl-3-aminoalkyl-1,2,3,4-tetrahydronaphthalenes and the salts thereof |
| US4055664A (en) * | 1975-02-10 | 1977-10-25 | Armour Pharmaceutical Company | Pharmaceutical preparations containing 4-(4-biphenylyl) butylamines and treatment of the animal organism therewith |
| DE3063585D1 (en) | 1979-05-19 | 1983-07-07 | Beecham Group Plc | Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them |
| JP2002363164A (ja) * | 2001-04-06 | 2002-12-18 | Mitsubishi Chemicals Corp | ピラゾールカルボキサミド類、その中間体およびこれを有効成分とする有害生物防除剤 |
| WO2003091189A1 (en) * | 2002-04-25 | 2003-11-06 | Virginia Commonwealth University | Cannabinoids |
| US20040087590A1 (en) * | 2002-08-23 | 2004-05-06 | University Of Connecticut | Novel biphenyl and biphenyl-like cannabinoids |
| ATE455096T1 (de) * | 2002-11-19 | 2010-01-15 | Galderma Res & Dev | Biaromatische verbindungen die ppar-gamma rezeptoren aktivieren und deren anwendungen in kosmetischen oder pharmazeutischen zusammensetzungen |
| WO2004052846A1 (en) * | 2002-12-06 | 2004-06-24 | Bayer Healthcare Ag | Tetrahydro-naphthalene derivatives |
| SE0300010D0 (sv) | 2003-01-07 | 2003-01-07 | Astrazeneca Ab | Novel Compounds |
-
2005
- 2005-10-03 US US11/242,318 patent/US7671052B2/en not_active Expired - Fee Related
- 2005-10-04 WO PCT/US2005/035677 patent/WO2006041841A1/en not_active Ceased
- 2005-10-04 JP JP2007535753A patent/JP2008515897A/ja active Pending
- 2005-10-04 MX MX2007003826A patent/MX2007003826A/es not_active Application Discontinuation
- 2005-10-04 BR BRPI0516544-0A patent/BRPI0516544A/pt not_active IP Right Cessation
- 2005-10-04 CA CA002583297A patent/CA2583297A1/en not_active Abandoned
- 2005-10-04 AU AU2005294459A patent/AU2005294459A1/en not_active Abandoned
- 2005-10-04 CN CN2005800340695A patent/CN101035758B/zh not_active Expired - Fee Related
- 2005-10-04 EP EP05810259A patent/EP1817277A4/en not_active Withdrawn
-
2010
- 2010-01-18 US US12/689,078 patent/US20100168108A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005294459A1 (en) | 2006-04-20 |
| US7671052B2 (en) | 2010-03-02 |
| JP2008515897A (ja) | 2008-05-15 |
| WO2006041841A1 (en) | 2006-04-20 |
| US20100168108A1 (en) | 2010-07-01 |
| MX2007003826A (es) | 2007-04-23 |
| EP1817277A1 (en) | 2007-08-15 |
| CN101035758A (zh) | 2007-09-12 |
| CN101035758B (zh) | 2010-12-01 |
| US20060074086A1 (en) | 2006-04-06 |
| BRPI0516544A (pt) | 2008-09-09 |
| EP1817277A4 (en) | 2010-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |