BRPI0516544A - composto, composição farmacêutica, método de aglutinação de receptores de canabinóides em um paciente e métodos para proteção, indução de apoptose e modulação do apetite - Google Patents

composto, composição farmacêutica, método de aglutinação de receptores de canabinóides em um paciente e métodos para proteção, indução de apoptose e modulação do apetite

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Publication number
BRPI0516544A
BRPI0516544A BRPI0516544-0A BRPI0516544A BRPI0516544A BR PI0516544 A BRPI0516544 A BR PI0516544A BR PI0516544 A BRPI0516544 A BR PI0516544A BR PI0516544 A BRPI0516544 A BR PI0516544A
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BR
Brazil
Prior art keywords
methods
disorders
patient
compound
protection
Prior art date
Application number
BRPI0516544-0A
Other languages
English (en)
Inventor
Roland E Dolle
Karin Worm
Q Jean Zhou
Original Assignee
Adolor Corp
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Publication date
Application filed by Adolor Corp filed Critical Adolor Corp
Publication of BRPI0516544A publication Critical patent/BRPI0516544A/pt

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Abstract

COMPOSTO, COMPOSIçãO FARMACêUTICA, MéTODO DE AGLUTINAçãO DE RECEPTORES DE CANABINóIDES EM UM PACIENTE E MéTODOS PARA PROTEçãO, INDUçãO DE APOPTOSE E MODULAçãO DO APETITE. Expõem-se novos compostos de fenilo, composições farmacêuticas que contêm esses compostos, e métodos para o seu uso farmacêutico. Em algumas concretizações, os compostos são agonistas e/ou ligantes de receptores de canabinóides e podem ser de utilidade ,inter alia, para tratamento e/ou prevenção de dor, distúrbios gastrintestinais, distúrbios geniturinários, inflamação, glaucoma, enfermidades de auto-imunização, condições isquêmicas, distúrbios relacionados com imunização, e enfermidades neuro-degenerativas, para proporcionar cardioproteção contra efeitos isquêmicos e de re-perfusão, para indução de apoptose em células malignas, e como um estimulante do apetite.
BRPI0516544-0A 2004-10-05 2005-10-04 composto, composição farmacêutica, método de aglutinação de receptores de canabinóides em um paciente e métodos para proteção, indução de apoptose e modulação do apetite BRPI0516544A (pt)

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US61602404P 2004-10-05 2004-10-05
US11/242,318 US7671052B2 (en) 2004-10-05 2005-10-03 Phenyl derivatives and methods of use
PCT/US2005/035677 WO2006041841A1 (en) 2004-10-05 2005-10-04 Phenyl derivatives and methods of use

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GB0427954D0 (en) * 2004-12-21 2005-01-26 Univ London Modulator
MX2008015501A (es) * 2006-06-08 2009-02-18 Neurokey As Uso de agonistas del receptor de canabinoide como farmacos inductores de hipotermia para el tratamiento de isquemia.
CA2679373A1 (en) * 2007-03-02 2008-09-12 The University Of Tennessee Research Foundation Tri-aryl/heteroaromatic cannabinoids and use thereof
EP2203165B1 (en) * 2007-08-07 2013-05-22 Stellenbosch University Paracetamol for use in treating glaucoma
EP2211619A1 (en) * 2007-10-18 2010-08-04 Merck Sharp & Dohme Corp. Substituted 1,2,4-oxadiazoles and analogs thereof as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases
WO2009140078A1 (en) * 2008-05-16 2009-11-19 The Procter & Gamble Company Treatment of lower urinary tract dysfunction with cb2-receptor-selective agonists
US20120029227A1 (en) * 2009-03-23 2012-02-02 Sumitomo Chemical Company, Limited Method for producing cyclopropanecarboxylic acid ester
US9855225B2 (en) * 2011-08-18 2018-01-02 Temple University Office Of Technology Transfer Cannabinoid receptor treatments
CN103288684B (zh) * 2013-05-03 2014-12-10 西安交通大学 一种具有抗肿瘤活性的联苯脲化合物及其制备方法
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
CN111479592B (zh) * 2017-11-15 2023-05-26 加利福尼亚大学董事会 阿片样物质使用障碍、阿片样物质戒断症状和慢性疼痛的治疗
EP4268811A1 (en) * 2020-12-25 2023-11-01 Amtixbio Co., Ltd. Novel derivative compound having biphenyl group introduced into amino-alkanoic acid and anti-inflammatory composition comprising same

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WO2006041841A1 (en) 2006-04-20
MX2007003826A (es) 2007-04-23
US20100168108A1 (en) 2010-07-01
EP1817277A1 (en) 2007-08-15
EP1817277A4 (en) 2010-03-10
US7671052B2 (en) 2010-03-02
US20060074086A1 (en) 2006-04-06
CN101035758A (zh) 2007-09-12
CN101035758B (zh) 2010-12-01
AU2005294459A1 (en) 2006-04-20
CA2583297A1 (en) 2006-04-20

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