CA2581939A1 - Polymeres diazeniumdiolates a base d'acrylonitrile liberant du monoxyde d'azote et compositions, dispositifs medicaux et utilisations correspondantes - Google Patents

Polymeres diazeniumdiolates a base d'acrylonitrile liberant du monoxyde d'azote et compositions, dispositifs medicaux et utilisations correspondantes Download PDF

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Publication number
CA2581939A1
CA2581939A1 CA002581939A CA2581939A CA2581939A1 CA 2581939 A1 CA2581939 A1 CA 2581939A1 CA 002581939 A CA002581939 A CA 002581939A CA 2581939 A CA2581939 A CA 2581939A CA 2581939 A1 CA2581939 A1 CA 2581939A1
Authority
CA
Canada
Prior art keywords
unsubstituted
substituted
carboxy
chain alkyl
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002581939A
Other languages
English (en)
Other versions
CA2581939C (fr
Inventor
Joseph A. Hrabie
Michael L. Citro
Frank Derosa
Larry K. Keefer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
Joseph A. Hrabie
Michael L. Citro
Frank Derosa
Larry K. Keefer
Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Joseph A. Hrabie, Michael L. Citro, Frank Derosa, Larry K. Keefer, Government Of The United States Of America, Represented By The Secretary , Department Of Health And Human Services filed Critical Joseph A. Hrabie
Publication of CA2581939A1 publication Critical patent/CA2581939A1/fr
Application granted granted Critical
Publication of CA2581939C publication Critical patent/CA2581939C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
CA2581939A 2004-09-27 2005-09-27 Polymeres diazeniumdiolates a base d'acrylonitrile liberant du monoxyde d'azote et compositions, dispositifs medicaux et utilisations correspondantes Expired - Fee Related CA2581939C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61325704P 2004-09-27 2004-09-27
US60/613,257 2004-09-27
PCT/US2005/035065 WO2006037105A2 (fr) 2004-09-27 2005-09-27 Polymeres diazeniumdiolates a base d'acrylonitrile liberant du monoxyde d'azote et compositions, dispositifs medicaux et utilisations correspondantes

Publications (2)

Publication Number Publication Date
CA2581939A1 true CA2581939A1 (fr) 2006-04-06
CA2581939C CA2581939C (fr) 2013-01-08

Family

ID=35954003

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2581939A Expired - Fee Related CA2581939C (fr) 2004-09-27 2005-09-27 Polymeres diazeniumdiolates a base d'acrylonitrile liberant du monoxyde d'azote et compositions, dispositifs medicaux et utilisations correspondantes

Country Status (5)

Country Link
US (2) US7968664B2 (fr)
EP (1) EP1794195B1 (fr)
AU (2) AU2005289414B2 (fr)
CA (1) CA2581939C (fr)
WO (1) WO2006037105A2 (fr)

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WO2007005758A2 (fr) * 2005-06-30 2007-01-11 Mc3, Inc. Procedes, compositions et dispositifs pour favoriser l'angiogenese
CA2613108A1 (fr) 2005-06-30 2007-01-11 Mc3, Inc. Revetements d'oxyde nitrique pour dispositifs medicaux
US8021679B2 (en) 2005-08-25 2011-09-20 Medtronic Vascular, Inc Nitric oxide-releasing biodegradable polymers useful as medical devices and coatings therefore
US20070053952A1 (en) * 2005-09-07 2007-03-08 Medtronic Vascular, Inc. Nitric oxide-releasing polymers derived from modified polymers
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US7811600B2 (en) 2007-03-08 2010-10-12 Medtronic Vascular, Inc. Nitric oxide donating medical devices and methods of making same
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US8852640B2 (en) * 2008-07-03 2014-10-07 Ecole Polytechnique Federale De Lausanne (Epfl) Micelles for delivery of nitric oxide
US8158187B2 (en) 2008-12-19 2012-04-17 Medtronic Vascular, Inc. Dry diazeniumdiolation methods for producing nitric oxide releasing medical devices
US8709465B2 (en) 2009-04-13 2014-04-29 Medtronic Vascular, Inc. Diazeniumdiolated phosphorylcholine polymers for nitric oxide release
EP2467127B1 (fr) 2009-08-21 2023-08-02 Novan, Inc. Gels topiques
WO2011022680A2 (fr) 2009-08-21 2011-02-24 Novan, Inc. Pansements, procédés d'utilisation de ceux-ci et procédés de formation de ceux-ci
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
ES2695173T3 (es) 2011-02-28 2019-01-02 Novan Inc Partículas de sílice modificadas con S-nitrosotiol que liberan óxido nítrico y procedimientos de fabricación de las mismas
EP2707103A2 (fr) 2011-05-09 2014-03-19 Topical Therapeutic Agent (TTA) Ltd. Formulations topiques capturant l'oxyde nitrique
US9017653B2 (en) 2012-06-14 2015-04-28 The Board Of Regents Of The University Of Texas System Nitric oxide-releasing compositions and methods
WO2014014978A1 (fr) * 2012-07-17 2014-01-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Polymères à base de polyvinylpyrrolidone diazéniumdiolés et libérant de l'oxyde nitrique, compositions, dispositifs médicaux et applications associées
EP3180366B1 (fr) * 2014-08-14 2018-09-26 Rohm and Haas Company Polymère contenant un gaz pouvant être libéré
AU2016320638B2 (en) 2015-09-09 2019-12-19 Beyond Air Ltd Nitric oxide inhalation therapy for infants with bronchiolitis
CN107446096B (zh) * 2017-09-01 2020-08-04 中车唐山机车车辆有限公司 重金属离子多孔吸附剂及其制备方法和应用

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WO2003026717A1 (fr) 2001-09-26 2003-04-03 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Dispositifs medicaux revetus a liberation d'oxyde nitrique et leur procede de preparation
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EP1308179A1 (fr) * 2001-10-30 2003-05-07 Boehringer Ingelheim Pharma GmbH & Co.KG Dispositif endoprothétique amélioré
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JP2005534485A (ja) * 2002-08-02 2005-11-17 アメリカ合衆国 架橋した一酸化窒素−放出ポリアミン被覆基質、それを含む組成物及びその製造方法
US20050043585A1 (en) * 2003-01-03 2005-02-24 Arindam Datta Reticulated elastomeric matrices, their manufacture and use in implantable devices
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Also Published As

Publication number Publication date
AU2011200972C1 (en) 2012-05-24
AU2011200972B2 (en) 2012-01-12
WO2006037105A3 (fr) 2007-10-04
AU2005289414B2 (en) 2010-12-09
US20070292471A1 (en) 2007-12-20
US8093343B2 (en) 2012-01-10
US20110282060A1 (en) 2011-11-17
AU2011200972A1 (en) 2011-03-24
EP1794195B1 (fr) 2014-12-17
EP1794195A2 (fr) 2007-06-13
US7968664B2 (en) 2011-06-28
AU2005289414A1 (en) 2006-04-06
WO2006037105A2 (fr) 2006-04-06
CA2581939C (fr) 2013-01-08

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Effective date: 20180927