CA2577999A1 - Conjugues d'hormone de croissance humaine polyethylene glycol ramifie, processus de preparation et procedes d'utilisation de ces conjugues - Google Patents
Conjugues d'hormone de croissance humaine polyethylene glycol ramifie, processus de preparation et procedes d'utilisation de ces conjugues Download PDFInfo
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- CA2577999A1 CA2577999A1 CA002577999A CA2577999A CA2577999A1 CA 2577999 A1 CA2577999 A1 CA 2577999A1 CA 002577999 A CA002577999 A CA 002577999A CA 2577999 A CA2577999 A CA 2577999A CA 2577999 A1 CA2577999 A1 CA 2577999A1
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- hgh
- peg
- growth hormone
- conjugate
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- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pregnancy & Childbirth (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US60594504P | 2004-08-31 | 2004-08-31 | |
US60/605,945 | 2004-08-31 | ||
PCT/IB2005/002939 WO2006024953A2 (fr) | 2004-08-31 | 2005-08-25 | Conjugues d'hormone de croissance humaine polyethylene glycol ramifie, processus de preparation et procedes d'utilisation de ces conjugues |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2577999A1 true CA2577999A1 (fr) | 2006-03-09 |
Family
ID=35708806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002577999A Abandoned CA2577999A1 (fr) | 2004-08-31 | 2005-08-25 | Conjugues d'hormone de croissance humaine polyethylene glycol ramifie, processus de preparation et procedes d'utilisation de ces conjugues |
Country Status (24)
Country | Link |
---|---|
EP (1) | EP1789092A2 (fr) |
JP (1) | JP2008511610A (fr) |
KR (1) | KR20070042567A (fr) |
CN (1) | CN101010105A (fr) |
AP (1) | AP2007003919A0 (fr) |
AR (1) | AR050851A1 (fr) |
AU (1) | AU2005278903A1 (fr) |
BR (1) | BRPI0515118A (fr) |
CA (1) | CA2577999A1 (fr) |
CR (1) | CR8942A (fr) |
EA (1) | EA200700380A1 (fr) |
EC (1) | ECSP077281A (fr) |
GT (1) | GT200500235A (fr) |
IL (1) | IL181085A0 (fr) |
MA (1) | MA28908B1 (fr) |
MX (1) | MX2007002441A (fr) |
NL (1) | NL1029828C2 (fr) |
NO (1) | NO20071322L (fr) |
PE (1) | PE20060654A1 (fr) |
TN (1) | TNSN07078A1 (fr) |
TW (1) | TW200621291A (fr) |
UY (1) | UY29088A1 (fr) |
WO (1) | WO2006024953A2 (fr) |
ZA (1) | ZA200701802B (fr) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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ES2297889T3 (es) | 1997-07-14 | 2008-05-01 | Bolder Biotechnology, Inc. | Derivados de hormona de crecimiento y proteinas relacionadas. |
US7495087B2 (en) | 1997-07-14 | 2009-02-24 | Bolder Biotechnology, Inc. | Cysteine muteins in the C-D loop of human interleukin-11 |
CA2359345A1 (fr) | 1999-01-14 | 2000-07-20 | Bolder Biotechnology, Inc. | Techniques permettant de produire des proteines contenant des residus cysteine libres |
US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
EP1834963A1 (fr) * | 2006-03-13 | 2007-09-19 | Siegfried Ltd. | Conjugues de proteines et de dipolymeres et leurs procedes de preparation |
CN101448525A (zh) * | 2006-05-12 | 2009-06-03 | 东亚制药株式会社 | 聚乙二醇-干扰素α缀合物 |
JP2008069073A (ja) * | 2006-09-12 | 2008-03-27 | Yokohama Tlo Co Ltd | ラクトフェリン複合体及びその製造方法 |
KR101079993B1 (ko) | 2006-11-17 | 2011-11-04 | 동아제약주식회사 | 폴리에틸렌글리콜 과립구 콜로니 자극인자 접합체 |
CL2008002399A1 (es) | 2007-08-16 | 2009-01-02 | Pharmaessentia Corp | Conjugado sustancialmente puro que posee una porcion polimerica, una porcion proteica (interferon alfa 2b) y un ligante alifatico de 1 a 10 atomos de carbono, util en el tratamiento de las hepatitis b o c. |
CA2731546C (fr) * | 2008-07-23 | 2013-11-19 | Hanmi Holdings Co., Ltd. | Complexe de polypeptide comprenant un polymere non-peptidylique ayant trois extremites fonctionnelles |
AR072850A1 (es) | 2008-07-31 | 2010-09-22 | Pharmaessentia Corp | Conjugados peptido-polimero |
SI2340271T1 (sl) | 2008-10-10 | 2019-08-30 | Polyactiva Pty Ltd. | Konjugati polimer-bioaktivnega sredstva |
US8535655B2 (en) | 2008-10-10 | 2013-09-17 | Polyactiva Pty Ltd. | Biodegradable polymer—bioactive moiety conjugates |
CA2949337C (fr) * | 2008-10-10 | 2019-03-26 | Polyactiva Pty Ltd | Conjugues polymere biodegradable - fractions bioactives |
US8680050B2 (en) | 2009-02-03 | 2014-03-25 | Amunix Operating Inc. | Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same |
US8703717B2 (en) | 2009-02-03 | 2014-04-22 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
CA2748314C (fr) | 2009-02-03 | 2018-10-02 | Amunix Operating Inc. | Polypeptides recombinants etendus et compositions les comprenant |
US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
US8841249B2 (en) | 2009-08-06 | 2014-09-23 | Novo Nordisk A/S | Growth hormones with prolonged in-vivo efficacy |
CN101831067A (zh) * | 2010-05-31 | 2010-09-15 | 王二新 | 聚乙二醇脂类缀合物及其在制备药物中的应用 |
EP2446898A1 (fr) | 2010-09-30 | 2012-05-02 | Laboratorios Del. Dr. Esteve, S.A. | Utilisation de l'hormone de croissance pour améliorer la réponse immunitaire chez des patients immunodéprimés |
CN102367290B (zh) * | 2011-04-26 | 2013-05-08 | 厦门赛诺邦格生物科技有限公司 | 链官能化的多级支化聚乙二醇及其合成方法 |
EP2947111B1 (fr) * | 2013-01-17 | 2018-03-07 | Xiamen Sinopeg Biotech Co., Ltd. | Polyéthylèneglycol ramifié monofonctionnel et substance de type biologique modifiée par celui-ci |
CN104877127B (zh) | 2015-06-23 | 2017-11-10 | 厦门赛诺邦格生物科技股份有限公司 | 一种八臂聚乙二醇衍生物、制备方法及其修饰的生物相关物质 |
KR102540109B1 (ko) | 2014-11-06 | 2023-06-02 | 파마에센시아 코퍼레이션 | Peg화된 인터페론의 투약 요법 |
HRP20220041T1 (hr) | 2017-12-29 | 2022-04-15 | F. Hoffmann - La Roche Ag | Postupak za dobivanje pegiliranog proteinskog pripravka |
HRP20220388T1 (hr) * | 2017-12-29 | 2022-05-27 | F. Hoffmann - La Roche Ag | Postupak za dobivanje pegiliranog proteinskog pripravka |
KR102523239B1 (ko) * | 2017-12-29 | 2023-04-18 | 에프. 호프만-라 로슈 아게 | 페길화 단백질 조성물을 제공하기 위한 방법 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993000109A1 (fr) * | 1991-06-28 | 1993-01-07 | Genentech, Inc. | Procede de stimulation de la reponse immunitaire a l'aide d'hormone de croissance |
JP3092531B2 (ja) * | 1996-11-05 | 2000-09-25 | 日本油脂株式会社 | コハク酸イミジル基置換ポリオキシアルキレン誘導体の製造方法 |
ES2297889T3 (es) * | 1997-07-14 | 2008-05-01 | Bolder Biotechnology, Inc. | Derivados de hormona de crecimiento y proteinas relacionadas. |
JP3921781B2 (ja) * | 1998-02-12 | 2007-05-30 | 日本油脂株式会社 | カルボキシル基含有ポリオキシアルキレン化合物 |
CA2359345A1 (fr) * | 1999-01-14 | 2000-07-20 | Bolder Biotechnology, Inc. | Techniques permettant de produire des proteines contenant des residus cysteine libres |
BR0214451A (pt) * | 2001-11-20 | 2006-05-30 | Pharmacia Corp | conjugados do hormÈnio do crescimento humano quimicamente modificado |
KR20050093856A (ko) * | 2002-09-09 | 2005-09-23 | 넥타르 테라퓨틱스 에이엘, 코포레이션 | 수용성 중합체 알카날 |
JP4412461B2 (ja) * | 2002-11-20 | 2010-02-10 | 日油株式会社 | 修飾された生体関連物質、その製造方法および中間体 |
EP1581260B1 (fr) * | 2002-12-31 | 2014-09-17 | Nektar Therapeutics | Reactifs polymeres comprenant une cetone ou un groupe fonctionnel apparente |
PT2644206T (pt) * | 2003-05-23 | 2019-07-10 | Nektar Therapeutics | Derivados de peg contendo duas cadeias de peg |
-
2005
- 2005-08-25 CN CNA2005800291171A patent/CN101010105A/zh active Pending
- 2005-08-25 MX MX2007002441A patent/MX2007002441A/es unknown
- 2005-08-25 EP EP05784225A patent/EP1789092A2/fr not_active Withdrawn
- 2005-08-25 WO PCT/IB2005/002939 patent/WO2006024953A2/fr active Application Filing
- 2005-08-25 CA CA002577999A patent/CA2577999A1/fr not_active Abandoned
- 2005-08-25 KR KR1020077004912A patent/KR20070042567A/ko not_active Application Discontinuation
- 2005-08-25 AP AP2007003919A patent/AP2007003919A0/xx unknown
- 2005-08-25 AU AU2005278903A patent/AU2005278903A1/en not_active Abandoned
- 2005-08-25 JP JP2007529040A patent/JP2008511610A/ja active Pending
- 2005-08-25 BR BRPI0515118-0A patent/BRPI0515118A/pt not_active IP Right Cessation
- 2005-08-25 EA EA200700380A patent/EA200700380A1/ru unknown
- 2005-08-26 PE PE2005000991A patent/PE20060654A1/es not_active Application Discontinuation
- 2005-08-29 UY UY29088A patent/UY29088A1/es not_active Application Discontinuation
- 2005-08-29 AR ARP050103612A patent/AR050851A1/es unknown
- 2005-08-30 GT GT200500235A patent/GT200500235A/es unknown
- 2005-08-30 TW TW094129583A patent/TW200621291A/zh unknown
- 2005-08-30 NL NL1029828A patent/NL1029828C2/nl not_active IP Right Cessation
-
2007
- 2007-01-31 IL IL181085A patent/IL181085A0/en unknown
- 2007-02-26 CR CR8942A patent/CR8942A/es not_active Application Discontinuation
- 2007-02-27 EC EC2007007281A patent/ECSP077281A/es unknown
- 2007-02-27 TN TNP2007000078A patent/TNSN07078A1/fr unknown
- 2007-02-28 ZA ZA200701802A patent/ZA200701802B/xx unknown
- 2007-02-28 MA MA29724A patent/MA28908B1/fr unknown
- 2007-03-09 NO NO20071322A patent/NO20071322L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA200701802B (en) | 2008-08-27 |
TW200621291A (en) | 2006-07-01 |
NO20071322L (no) | 2007-05-29 |
CR8942A (es) | 2007-08-16 |
UY29088A1 (es) | 2006-03-31 |
AR050851A1 (es) | 2006-11-29 |
AP2007003919A0 (en) | 2007-02-28 |
KR20070042567A (ko) | 2007-04-23 |
TNSN07078A1 (fr) | 2008-06-02 |
GT200500235A (es) | 2006-03-21 |
CN101010105A (zh) | 2007-08-01 |
MA28908B1 (fr) | 2007-10-01 |
IL181085A0 (en) | 2007-07-04 |
MX2007002441A (es) | 2007-05-04 |
AU2005278903A1 (en) | 2006-03-09 |
WO2006024953A2 (fr) | 2006-03-09 |
NL1029828A1 (nl) | 2006-03-01 |
JP2008511610A (ja) | 2008-04-17 |
NL1029828C2 (nl) | 2006-10-20 |
BRPI0515118A (pt) | 2008-07-01 |
EA200700380A1 (ru) | 2007-10-26 |
EP1789092A2 (fr) | 2007-05-30 |
PE20060654A1 (es) | 2006-08-12 |
WO2006024953A3 (fr) | 2007-01-18 |
ECSP077281A (es) | 2007-03-29 |
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