CA2576952A1 - Methods for producing isoindole derivatives - Google Patents
Methods for producing isoindole derivatives Download PDFInfo
- Publication number
- CA2576952A1 CA2576952A1 CA002576952A CA2576952A CA2576952A1 CA 2576952 A1 CA2576952 A1 CA 2576952A1 CA 002576952 A CA002576952 A CA 002576952A CA 2576952 A CA2576952 A CA 2576952A CA 2576952 A1 CA2576952 A1 CA 2576952A1
- Authority
- CA
- Canada
- Prior art keywords
- acid
- compound
- palladium
- solvent
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004236645 | 2004-08-16 | ||
| JP2004-236645 | 2004-08-16 | ||
| PCT/JP2005/013696 WO2006018955A1 (ja) | 2004-08-16 | 2005-07-27 | イソインドール誘導体の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2576952A1 true CA2576952A1 (en) | 2006-02-23 |
Family
ID=35907346
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002576952A Abandoned CA2576952A1 (en) | 2004-08-16 | 2005-07-27 | Methods for producing isoindole derivatives |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7585982B2 (zh) |
| EP (1) | EP1787983B1 (zh) |
| JP (1) | JP4820295B2 (zh) |
| KR (1) | KR20070062520A (zh) |
| CN (1) | CN101056853B (zh) |
| AT (1) | ATE501120T1 (zh) |
| AU (1) | AU2005273430B2 (zh) |
| CA (1) | CA2576952A1 (zh) |
| DE (1) | DE602005026827D1 (zh) |
| IL (1) | IL181196A (zh) |
| WO (1) | WO2006018955A1 (zh) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004218187C1 (en) | 2003-02-19 | 2011-04-07 | Eisai R&D Management Co., Ltd. | Methods for producing cyclic benzamidine derivatives |
| WO2006018954A1 (ja) * | 2004-08-17 | 2006-02-23 | Eisai R & D Management Co., Ltd. | ジブロモフルオロベンゼン誘導体の製造方法 |
| US7786330B2 (en) | 2005-02-28 | 2010-08-31 | Asahi Glass Company, Limited | Process for producing 1,2-dialkoxy-3-fluorobenzene |
| EP2055692A4 (en) * | 2006-08-25 | 2010-07-07 | Asahi Glass Co Ltd | PROCESS FOR PRODUCING 1,2-DIALCOXY-3-FLUOROBENZENE |
| JP2011511018A (ja) | 2008-02-05 | 2011-04-07 | サノフィ−アベンティス | Ｐａｒ１阻害剤としてのｓｆ５誘導体、その製造、及び薬剤としての使用 |
| US8673890B2 (en) | 2009-10-29 | 2014-03-18 | Janssen Pharmaceutica Nv | 2,3-dihydro-1H-isoindol-1-imine derivatives useful as thrombin PAR-1 receptor antagonist |
| JPWO2012014889A1 (ja) * | 2010-07-29 | 2013-09-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | フタロニトリル誘導体の製造方法 |
| RU2710230C1 (ru) | 2016-05-04 | 2019-12-25 | Юнджин Терапьютикс Ко., Лтд. | Аминный сольват ингибитора натрий-глюкозного котранспортера и способ его получения и его применение |
| CN106083692B (zh) * | 2016-05-26 | 2019-04-26 | 苏州大学 | 一种2-(2-芳基异吲哚-1-亚基)丙二腈类化合物的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2805535B1 (fr) * | 2000-02-25 | 2002-04-12 | Adir | Nouveau procede de preparation de l'isoindoline |
| DE60233043D1 (de) * | 2001-04-19 | 2009-09-03 | Eisai R&D Man Co Ltd | 2-iminoimidazolderivate |
| AU2004218187C1 (en) | 2003-02-19 | 2011-04-07 | Eisai R&D Management Co., Ltd. | Methods for producing cyclic benzamidine derivatives |
| WO2006018954A1 (ja) | 2004-08-17 | 2006-02-23 | Eisai R & D Management Co., Ltd. | ジブロモフルオロベンゼン誘導体の製造方法 |
-
2005
- 2005-07-27 US US11/573,814 patent/US7585982B2/en not_active Expired - Fee Related
- 2005-07-27 EP EP05766977A patent/EP1787983B1/en active Active
- 2005-07-27 CA CA002576952A patent/CA2576952A1/en not_active Abandoned
- 2005-07-27 JP JP2006531410A patent/JP4820295B2/ja not_active Expired - Fee Related
- 2005-07-27 KR KR1020077006153A patent/KR20070062520A/ko active IP Right Grant
- 2005-07-27 AU AU2005273430A patent/AU2005273430B2/en not_active Ceased
- 2005-07-27 DE DE602005026827T patent/DE602005026827D1/de active Active
- 2005-07-27 WO PCT/JP2005/013696 patent/WO2006018955A1/ja active Application Filing
- 2005-07-27 AT AT05766977T patent/ATE501120T1/de not_active IP Right Cessation
- 2005-07-27 CN CN2005800348659A patent/CN101056853B/zh not_active Expired - Fee Related
-
2007
- 2007-02-07 IL IL181196A patent/IL181196A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005273430A1 (en) | 2006-02-23 |
| EP1787983B1 (en) | 2011-03-09 |
| ATE501120T1 (de) | 2011-03-15 |
| DE602005026827D1 (de) | 2011-04-21 |
| KR20070062520A (ko) | 2007-06-15 |
| JPWO2006018955A1 (ja) | 2008-05-08 |
| EP1787983A1 (en) | 2007-05-23 |
| IL181196A0 (en) | 2007-07-04 |
| JP4820295B2 (ja) | 2011-11-24 |
| IL181196A (en) | 2012-06-28 |
| EP1787983A4 (en) | 2009-06-24 |
| US7585982B2 (en) | 2009-09-08 |
| AU2005273430B2 (en) | 2011-06-30 |
| WO2006018955A1 (ja) | 2006-02-23 |
| CN101056853B (zh) | 2010-05-05 |
| CN101056853A (zh) | 2007-10-17 |
| US20080214834A1 (en) | 2008-09-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20130729 |