CA2571365A1 - Human autism predisposition gene encoding a transcription factor and uses thereof - Google Patents

Human autism predisposition gene encoding a transcription factor and uses thereof Download PDF

Info

Publication number
CA2571365A1
CA2571365A1 CA002571365A CA2571365A CA2571365A1 CA 2571365 A1 CA2571365 A1 CA 2571365A1 CA 002571365 A CA002571365 A CA 002571365A CA 2571365 A CA2571365 A CA 2571365A CA 2571365 A1 CA2571365 A1 CA 2571365A1
Authority
CA
Canada
Prior art keywords
autism
pitx1
gene
disorder
alteration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002571365A
Other languages
English (en)
French (fr)
Inventor
Anne Philippi
Francis Rousseau
Peter Brooks
Joerg Hager
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IntegraGen SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2571365A1 publication Critical patent/CA2571365A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/136Screening for pharmacological compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
CA002571365A 2004-07-01 2005-06-30 Human autism predisposition gene encoding a transcription factor and uses thereof Abandoned CA2571365A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58413004P 2004-07-01 2004-07-01
US60/584,130 2004-07-01
PCT/IB2005/002319 WO2006003520A2 (en) 2004-07-01 2005-06-30 Human autism predisposition gene encoding a transcription factor and uses thereof

Publications (1)

Publication Number Publication Date
CA2571365A1 true CA2571365A1 (en) 2006-01-12

Family

ID=35432082

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002571365A Abandoned CA2571365A1 (en) 2004-07-01 2005-06-30 Human autism predisposition gene encoding a transcription factor and uses thereof

Country Status (10)

Country Link
US (1) US20070218068A1 (https=)
EP (1) EP1761649B1 (https=)
JP (1) JP4949240B2 (https=)
AT (1) ATE382101T1 (https=)
AU (1) AU2005258838B2 (https=)
CA (1) CA2571365A1 (https=)
DE (1) DE602005004026T2 (https=)
ES (1) ES2299059T3 (https=)
IL (1) IL179751A (https=)
WO (1) WO2006003520A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110118135A1 (en) * 2008-01-09 2011-05-19 State Matthew W Mutations in Contaction Associated Protein 2 (CNTNAP2) are Associated with Increased Risk for Ideopathic Autism
WO2009150221A1 (en) * 2008-06-12 2009-12-17 Integragen A method for autism prediction
EP2963129A3 (en) * 2008-11-12 2016-05-11 University of Utah Research Foundation Autism associated genetic markers
WO2011067296A1 (en) 2009-12-01 2011-06-09 Integragen A combination of eight risk alleles associated with autism
KR101167942B1 (ko) 2010-02-12 2012-07-23 차의과학대학교 산학협력단 Alg12 유전자로부터 유래된 단일염기다형을 포함하는 폴리뉴클레오티드, 이를 포함하는 마이크로어레이 및 진단키트, 및 이를 이용한 자폐 스펙트럼 장애 분석방법
CA2797319A1 (en) 2010-05-04 2011-11-10 Integragen A new combination of eight risk alleles associated with autism
EP2860265B1 (en) 2011-02-24 2016-10-26 The Chinese University of Hong Kong Determining fetal DNA percentage for twins
CN111808943B (zh) * 2020-06-18 2021-07-20 重庆浦洛通基因医学研究院有限公司 一种精神类个体化用药基因检测方法

Also Published As

Publication number Publication date
DE602005004026T2 (de) 2008-12-24
EP1761649A2 (en) 2007-03-14
ES2299059T3 (es) 2008-05-16
EP1761649B1 (en) 2007-12-26
WO2006003520A2 (en) 2006-01-12
AU2005258838B2 (en) 2009-05-14
IL179751A0 (en) 2007-05-15
US20070218068A1 (en) 2007-09-20
JP4949240B2 (ja) 2012-06-06
WO2006003520A3 (en) 2006-03-02
JP2008504837A (ja) 2008-02-21
DE602005004026D1 (de) 2008-02-07
IL179751A (en) 2011-01-31
ATE382101T1 (de) 2008-01-15
AU2005258838A1 (en) 2006-01-12

Similar Documents

Publication Publication Date Title
US20100240539A1 (en) Human Autism Susceptibility Gene Encoding PRKCB1 and Uses Thereof
EP1656458B1 (en) Human autism susceptibility gene and uses thereof
AU2005258838B2 (en) Human autism predisposition gene encoding a transcription factor and uses thereof
AU2006215385B2 (en) Uses of human autism susceptibility gene encoding a kinase
US20080213765A1 (en) Human Autism Susceptibility Genes Encoding a Neurotransmitter Transporter and Uses Thereof
AU2006225995B2 (en) Human autism susceptibility gene encoding a transmembrane protein and uses thereof
AU2005254806B2 (en) Human obesity susceptibility gene encoding a potassium voltage-gated channel and uses thereof
WO2006003526A2 (en) Human autism susceptibility gene encoding otoa and uses thereof
AU2005254805B2 (en) Human obesity susceptibility gene encoding a taste receptor and uses thereof
CA2586092A1 (en) Human obesity susceptibility gene encoding a member of the neurexin family and uses thereof

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140702