CA2559167A1 - Modified annexin proteins and methods for preventing thrombosis - Google Patents
Modified annexin proteins and methods for preventing thrombosis Download PDFInfo
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- CA2559167A1 CA2559167A1 CA002559167A CA2559167A CA2559167A1 CA 2559167 A1 CA2559167 A1 CA 2559167A1 CA 002559167 A CA002559167 A CA 002559167A CA 2559167 A CA2559167 A CA 2559167A CA 2559167 A1 CA2559167 A1 CA 2559167A1
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- Prior art keywords
- annexin
- protein
- nucleic acid
- modified
- thrombosis
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4721—Lipocortins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- Hematology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55242804P | 2004-03-11 | 2004-03-11 | |
| US60/552,428 | 2004-03-11 | ||
| US57958904P | 2004-06-14 | 2004-06-14 | |
| US60/579,589 | 2004-06-14 | ||
| PCT/US2005/008193 WO2005086955A2 (en) | 2004-03-11 | 2005-03-10 | Modified annexin proteins and methods for preventing thrombosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2559167A1 true CA2559167A1 (en) | 2005-09-22 |
Family
ID=34976262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002559167A Abandoned CA2559167A1 (en) | 2004-03-11 | 2005-03-10 | Modified annexin proteins and methods for preventing thrombosis |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1734983A4 (enExample) |
| JP (2) | JP5134362B2 (enExample) |
| AU (1) | AU2005221195B2 (enExample) |
| CA (1) | CA2559167A1 (enExample) |
| WO (1) | WO2005086955A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022263407A3 (en) * | 2021-06-14 | 2023-02-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Mutated annexin a5 polypeptides and uses thereof for therapeutic purposes |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7645739B2 (en) * | 2001-02-21 | 2010-01-12 | Alavita Pharmaceuticals, Inc. | Modified annexin compositions and methods of using same |
| US7635676B2 (en) * | 2001-02-21 | 2009-12-22 | Alavita Pharmaccuticals, Inc. | Modified annexin proteins and methods for their use in organ transplantation |
| EP2328622B1 (en) | 2008-08-26 | 2014-12-17 | MosaMedix B.V. | Radiolabelled annexins |
| WO2013022328A1 (en) * | 2011-08-09 | 2013-02-14 | Uab Profarma | Derivatives of recombinant proteins, homo-multimers of granulocyte colony-stimulating factor and method of preparation thereof |
| GB2542391A (en) * | 2015-09-17 | 2017-03-22 | Annexin Pharmaceuticals Ab | Process of manufacture |
| US11357823B2 (en) * | 2019-08-30 | 2022-06-14 | Suzhou Yabao Pharmaceutical R&D Co., Ltd | Method for treating cerebral stroke |
| TW202146042A (zh) * | 2020-03-06 | 2021-12-16 | 瑞典商阿斯特捷利康公司 | 用於治療動脈和靜脈血栓形成的協同且靶向的組成物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968477A (en) * | 1994-01-24 | 1999-10-19 | Neorx Corporation | Radiolabeled annexin conjugates with hexose and a chelator |
| JP3742675B2 (ja) * | 1995-06-28 | 2006-02-08 | 東菱薬品工業株式会社 | 虚血−再灌流障害の予防および治療薬 |
| CA2331789C (en) * | 1998-07-13 | 2013-09-10 | Board Of Regents, The University Of Texas System | Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids |
| CN1125084C (zh) * | 1999-03-12 | 2003-10-22 | 中国科学院上海生物化学研究所 | 一种血栓靶向性溶栓融合蛋白 |
| EP1839670A3 (en) * | 2001-02-21 | 2009-11-11 | Alavita Pharmaceuticals, Inc. | Modified Annexin Proteins and their use against thrombosis |
| US20030152513A1 (en) * | 2001-09-06 | 2003-08-14 | Imetrix, Inc. | Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector |
| WO2003103577A2 (en) * | 2002-06-06 | 2003-12-18 | Tze Chein Wun | Novel recombinant anticoagulant proteins |
| WO2004013303A2 (en) * | 2002-08-02 | 2004-02-12 | Surromed, Inc. | Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease |
-
2005
- 2005-03-10 CA CA002559167A patent/CA2559167A1/en not_active Abandoned
- 2005-03-10 AU AU2005221195A patent/AU2005221195B2/en not_active Ceased
- 2005-03-10 JP JP2007503052A patent/JP5134362B2/ja not_active Expired - Fee Related
- 2005-03-10 WO PCT/US2005/008193 patent/WO2005086955A2/en not_active Ceased
- 2005-03-10 EP EP05725390A patent/EP1734983A4/en not_active Withdrawn
-
2012
- 2012-07-20 JP JP2012161761A patent/JP2012254992A/ja not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022263407A3 (en) * | 2021-06-14 | 2023-02-02 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Mutated annexin a5 polypeptides and uses thereof for therapeutic purposes |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005086955A2 (en) | 2005-09-22 |
| AU2005221195A1 (en) | 2005-09-22 |
| EP1734983A2 (en) | 2006-12-27 |
| JP2008502592A (ja) | 2008-01-31 |
| AU2005221195B2 (en) | 2011-05-19 |
| EP1734983A4 (en) | 2009-11-18 |
| JP2012254992A (ja) | 2012-12-27 |
| JP5134362B2 (ja) | 2013-01-30 |
| WO2005086955A3 (en) | 2006-03-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Dead |
Effective date: 20140311 |