CA2559167A1 - Proteines d'annexine modifiees et procedes destines a prevenir la thrombose - Google Patents

Proteines d'annexine modifiees et procedes destines a prevenir la thrombose Download PDF

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Publication number
CA2559167A1
CA2559167A1 CA002559167A CA2559167A CA2559167A1 CA 2559167 A1 CA2559167 A1 CA 2559167A1 CA 002559167 A CA002559167 A CA 002559167A CA 2559167 A CA2559167 A CA 2559167A CA 2559167 A1 CA2559167 A1 CA 2559167A1
Authority
CA
Canada
Prior art keywords
annexin
protein
nucleic acid
modified
thrombosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002559167A
Other languages
English (en)
Inventor
Anthony Allison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alavita Pharmaceuticals Inc
Original Assignee
Alavita, Inc.
Anthony Allison
Alavita Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alavita, Inc., Anthony Allison, Alavita Pharmaceuticals, Inc. filed Critical Alavita, Inc.
Publication of CA2559167A1 publication Critical patent/CA2559167A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721—Lipocortins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002559167A 2004-03-11 2005-03-10 Proteines d'annexine modifiees et procedes destines a prevenir la thrombose Abandoned CA2559167A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55242804P 2004-03-11 2004-03-11
US60/552,428 2004-03-11
US57958904P 2004-06-14 2004-06-14
US60/579,589 2004-06-14
PCT/US2005/008193 WO2005086955A2 (fr) 2004-03-11 2005-03-10 Proteines d'annexine modifiees et procedes destines a prevenir la thrombose

Publications (1)

Publication Number Publication Date
CA2559167A1 true CA2559167A1 (fr) 2005-09-22

Family

ID=34976262

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002559167A Abandoned CA2559167A1 (fr) 2004-03-11 2005-03-10 Proteines d'annexine modifiees et procedes destines a prevenir la thrombose

Country Status (5)

Country Link
EP (1) EP1734983A4 (fr)
JP (2) JP5134362B2 (fr)
AU (1) AU2005221195B2 (fr)
CA (1) CA2559167A1 (fr)
WO (1) WO2005086955A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022263407A3 (fr) * 2021-06-14 2023-02-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides d'annexine a5 mutants et leurs utilisations à des fins thérapeutiques

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635676B2 (en) * 2001-02-21 2009-12-22 Alavita Pharmaccuticals, Inc. Modified annexin proteins and methods for their use in organ transplantation
US7645739B2 (en) * 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
US8747808B2 (en) 2008-08-26 2014-06-10 Mosamedix B.V. Radiolabeled annexins
CN103717614A (zh) * 2011-08-09 2014-04-09 普罗法尔马封闭式股份公司 重组蛋白质的衍生物、粒细胞集落刺激因子的同多聚体及其制备方法
GB2542391A (en) * 2015-09-17 2017-03-22 Annexin Pharmaceuticals Ab Process of manufacture
US11357823B2 (en) * 2019-08-30 2022-06-14 Suzhou Yabao Pharmaceutical R&D Co., Ltd Method for treating cerebral stroke

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5968477A (en) * 1994-01-24 1999-10-19 Neorx Corporation Radiolabeled annexin conjugates with hexose and a chelator
JP3742675B2 (ja) * 1995-06-28 2006-02-08 東菱薬品工業株式会社 虚血−再灌流障害の予防および治療薬
IL140700A0 (en) * 1998-07-13 2002-02-10 Univ Texas Cancer treatment methods using therapeutic conjugates that bind to aminophospholipids
CN1125084C (zh) * 1999-03-12 2003-10-22 中国科学院上海生物化学研究所 一种血栓靶向性溶栓融合蛋白
EP1379266B1 (fr) * 2001-02-21 2007-04-18 SurroMed, Inc. Annexines modifiees et prevention de la thrombose
US20030152513A1 (en) * 2001-09-06 2003-08-14 Imetrix, Inc. Intravascular delivery of therapeutic and imaging agents to stressed and apoptotic cells using annexin V as a targeting vector
ATE534658T1 (de) * 2002-06-06 2011-12-15 Tze Chein Wun Neue rekombinante antikoagulationsproteine
WO2004013303A2 (fr) * 2002-08-02 2004-02-12 Surromed, Inc. Proteines d'annexine modifiees, et procedes de traitement de la drepanocytose a crise vaso-occlusive

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022263407A3 (fr) * 2021-06-14 2023-02-02 INSERM (Institut National de la Santé et de la Recherche Médicale) Polypeptides d'annexine a5 mutants et leurs utilisations à des fins thérapeutiques

Also Published As

Publication number Publication date
JP5134362B2 (ja) 2013-01-30
JP2008502592A (ja) 2008-01-31
AU2005221195B2 (en) 2011-05-19
EP1734983A2 (fr) 2006-12-27
AU2005221195A1 (en) 2005-09-22
WO2005086955A2 (fr) 2005-09-22
EP1734983A4 (fr) 2009-11-18
WO2005086955A3 (fr) 2006-03-09
JP2012254992A (ja) 2012-12-27

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead

Effective date: 20140311