CA2557788A1 - Mutein of a bone morphogenetic protein and use thereof - Google Patents
Mutein of a bone morphogenetic protein and use thereof Download PDFInfo
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- CA2557788A1 CA2557788A1 CA002557788A CA2557788A CA2557788A1 CA 2557788 A1 CA2557788 A1 CA 2557788A1 CA 002557788 A CA002557788 A CA 002557788A CA 2557788 A CA2557788 A CA 2557788A CA 2557788 A1 CA2557788 A1 CA 2557788A1
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- bone morphogenetic
- amino acid
- mutein
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Cardiology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04005192.2 | 2004-03-04 | ||
| EP04005192A EP1571159A1 (en) | 2004-03-04 | 2004-03-04 | Mutein of a bone morphogenetic protein and use thereof |
| PCT/EP2005/002328 WO2005085281A1 (en) | 2004-03-04 | 2005-03-04 | Mutein of a bone morphogenetic protein and use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2557788A1 true CA2557788A1 (en) | 2005-09-15 |
Family
ID=34746006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002557788A Abandoned CA2557788A1 (en) | 2004-03-04 | 2005-03-04 | Mutein of a bone morphogenetic protein and use thereof |
Country Status (6)
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1571159A1 (en) | 2004-03-04 | 2005-09-07 | Bayerische Julius-Maximilians-Universität Würzburg | Mutein of a bone morphogenetic protein and use thereof |
| US20090042780A1 (en) * | 2004-05-20 | 2009-02-12 | Acceleron Pharma Inc | Modified TGF-Beta Superfamily Polypeptides and Related Methods |
| JP2008509087A (ja) * | 2004-05-27 | 2008-03-27 | アクセルロン ファーマ インコーポレーテッド | Ｔｇｆ抑制解除因子およびそれに関連する使用方法 |
| US7771995B2 (en) | 2005-11-14 | 2010-08-10 | Merial Limited | Plasmid encoding human BMP-7 |
| EP3147296A1 (en) | 2005-11-14 | 2017-03-29 | Merial, Inc. | Gene therapy for renal failure |
| CN101301467B (zh) * | 2008-04-22 | 2012-01-25 | 同济大学 | Bmp-7在制备预防和/或治疗肝纤维化药物中的应用 |
| US11078248B2 (en) | 2010-03-19 | 2021-08-03 | Lifenet Health | BMP peptides and methods of use |
| US9688735B2 (en) | 2010-08-20 | 2017-06-27 | Wyeth Llc | Designer osteogenic proteins |
| US9856305B2 (en) | 2010-08-20 | 2018-01-02 | Wyeth Llc | Designer osteogenic proteins |
| AU2015202418B2 (en) * | 2010-08-20 | 2017-02-02 | Wyeth Llc | Designer osteogenic proteins |
| SG187589A1 (en) * | 2010-08-20 | 2013-03-28 | Wyeth Llc | Designer osteogenic proteins |
| US20150064163A1 (en) | 2011-09-02 | 2015-03-05 | Lifenet Health | BMP Peptides & Methods of Use |
| EP2602264A1 (en) | 2011-12-05 | 2013-06-12 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka mbH | GDF-5 mutant for inducing cartilage formation |
| GB201412290D0 (en) | 2014-07-10 | 2014-08-27 | Cambridge Entpr Ltd | Novel use |
| KR20180014714A (ko) | 2015-06-05 | 2018-02-09 | 노파르티스 아게 | 골 형태형성 단백질 9 (bmp9)를 표적화하는 항체 및 그에 대한 방법 |
| GB201621635D0 (en) | 2016-12-19 | 2017-02-01 | Ucb Biopharma Sprl | Crystal structure |
| US20200121760A1 (en) * | 2017-01-04 | 2020-04-23 | The Trustees Of The University Ofpennsylvania | Methods for scar reduction by converting scar fibroblasts into adipocytes with hair follicle-derived signals |
| US11596712B2 (en) | 2017-10-19 | 2023-03-07 | Genera Istrazivanja D.O.O. | Autologous bone graft substitute composition |
| GB201802486D0 (en) * | 2018-02-15 | 2018-04-04 | Ucb Biopharma Sprl | Methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5631142A (en) * | 1986-07-01 | 1997-05-20 | Genetics Institute, Inc. | Compositions comprising bone morphogenetic protein-2 (BMP-2) |
| IL83003A (en) * | 1986-07-01 | 1995-07-31 | Genetics Inst | Factors that soak bone formation |
| US5304541A (en) | 1988-12-15 | 1994-04-19 | Bristol-Myers Squibb Company | Methods using novel chimeric transforming growth factor-β1/β2 |
| DE69528128T2 (de) | 1994-06-10 | 2003-03-13 | United States Surgical Corp | Rekombinante Chimäre Proteine und Verfahren zur deren Verwendung |
| US5965403A (en) | 1996-09-18 | 1999-10-12 | Genetics Institute, Inc. | Nucleic acids encoding bone morphogenic protein-16 (BMP-16) |
| US6743613B2 (en) | 1999-04-23 | 2004-06-01 | Human Genome Sciences, Inc. | Lysyl-oxidase HOHEC84 polynucleotides |
| DE10026713A1 (de) | 2000-05-30 | 2001-12-06 | Walter Sebald | Mutein einer Kette eines Proteins aus der Superfamilie des Wachstumsfaktors TGF-beta |
| EP1571159A1 (en) | 2004-03-04 | 2005-09-07 | Bayerische Julius-Maximilians-Universität Würzburg | Mutein of a bone morphogenetic protein and use thereof |
| US20090042780A1 (en) | 2004-05-20 | 2009-02-12 | Acceleron Pharma Inc | Modified TGF-Beta Superfamily Polypeptides and Related Methods |
| JP2008509087A (ja) | 2004-05-27 | 2008-03-27 | アクセルロン ファーマ インコーポレーテッド | Ｔｇｆ抑制解除因子およびそれに関連する使用方法 |
-
2004
- 2004-03-04 EP EP04005192A patent/EP1571159A1/en not_active Withdrawn
-
2005
- 2005-03-04 AU AU2005219556A patent/AU2005219556B2/en not_active Ceased
- 2005-03-04 WO PCT/EP2005/002328 patent/WO2005085281A1/en active Application Filing
- 2005-03-04 US US10/591,482 patent/US7786080B2/en not_active Expired - Fee Related
- 2005-03-04 JP JP2007501236A patent/JP2008501309A/ja active Pending
- 2005-03-04 EP EP05715753A patent/EP1720902A1/en not_active Withdrawn
- 2005-03-04 CA CA002557788A patent/CA2557788A1/en not_active Abandoned
-
2012
- 2012-07-06 JP JP2012152866A patent/JP2012235784A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005219556B2 (en) | 2012-03-01 |
| AU2005219556A1 (en) | 2005-09-15 |
| JP2012235784A (ja) | 2012-12-06 |
| EP1720902A1 (en) | 2006-11-15 |
| US20070293425A1 (en) | 2007-12-20 |
| US7786080B2 (en) | 2010-08-31 |
| EP1571159A1 (en) | 2005-09-07 |
| WO2005085281A1 (en) | 2005-09-15 |
| JP2008501309A (ja) | 2008-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20130603 |