CA2552907A1 - Beta-ketoamide compounds having an mch-antagonistic effect and medicaments containing said compounds - Google Patents
Beta-ketoamide compounds having an mch-antagonistic effect and medicaments containing said compounds Download PDFInfo
- Publication number
- CA2552907A1 CA2552907A1 CA002552907A CA2552907A CA2552907A1 CA 2552907 A1 CA2552907 A1 CA 2552907A1 CA 002552907 A CA002552907 A CA 002552907A CA 2552907 A CA2552907 A CA 2552907A CA 2552907 A1 CA2552907 A1 CA 2552907A1
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- Prior art keywords
- alkyl
- group
- amino
- atoms
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 125000004432 carbon atom Chemical group C* 0.000 claims description 140
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- 125000003774 valeryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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Classifications
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- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/45—Monoamines
- C07C211/46—Aniline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/72—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms
- C07C235/80—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atoms of the carboxamide groups bound to acyclic carbon atoms having carbon atoms of carboxamide groups and keto groups bound to the same carbon atom, e.g. acetoacetamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/56—Benzoxazoles; Hydrogenated benzoxazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
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- Neurology (AREA)
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- Cardiology (AREA)
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- Psychiatry (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
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- Addiction (AREA)
- Vascular Medicine (AREA)
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- Emergency Medicine (AREA)
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- Gynecology & Obstetrics (AREA)
- Reproductive Health (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102004010893A DE102004010893A1 (de) | 2004-03-06 | 2004-03-06 | Neue ß-Ketoamid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| DE102004010893.5 | 2004-03-06 | ||
| PCT/EP2005/002132 WO2005085221A1 (de) | 2004-03-06 | 2005-03-01 | Beta-ketoamid-verbindungen mit mch-antagonistischer wirkung und diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2552907A1 true CA2552907A1 (en) | 2005-09-15 |
Family
ID=34877445
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002552907A Abandoned CA2552907A1 (en) | 2004-03-06 | 2005-03-01 | Beta-ketoamide compounds having an mch-antagonistic effect and medicaments containing said compounds |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1730130A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2007527424A (cg-RX-API-DMAC7.html) |
| AR (1) | AR048254A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2552907A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE102004010893A1 (cg-RX-API-DMAC7.html) |
| PE (1) | PE20060001A1 (cg-RX-API-DMAC7.html) |
| TW (1) | TW200540142A (cg-RX-API-DMAC7.html) |
| UY (1) | UY28790A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2005085221A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7351719B2 (en) | 2002-10-31 | 2008-04-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds |
| US7592373B2 (en) | 2003-12-23 | 2009-09-22 | Boehringer Ingelheim International Gmbh | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds |
| US7553836B2 (en) * | 2006-02-06 | 2009-06-30 | Bristol-Myers Squibb Company | Melanin concentrating hormone receptor-1 antagonists |
| JP5073746B2 (ja) | 2006-08-25 | 2012-11-14 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｍｃｈ拮抗作用を有する新規ピリドン誘導体及びこの化合物を含む薬物 |
| CA2671984A1 (en) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim International Gmbh | New pyridazine derivatives with mch antagonistic activity and medicaments comprising these compounds |
| DE602008002933D1 (de) * | 2007-05-03 | 2010-11-18 | Neurosearch As | Als ionenkanalmodulatoren geeignete beta-ketoamidderivate |
| EP2593093A1 (en) * | 2010-07-16 | 2013-05-22 | Merz Pharma GmbH & Co. KGaA | Use of a cationic amphiphilic drug for the preparation of a formulation for the reduction of subcutaneous adipose tissue |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2589004A (en) * | 1948-11-04 | 1952-03-11 | Eastman Kodak Co | Process for producing couplers from bi-functional amines |
| GB784422A (en) * | 1955-01-29 | 1957-10-09 | Ilford Ltd | Improvements in or relating to colour photography |
| US3341532A (en) * | 1967-02-15 | 1967-09-12 | American Cyanamid Co | Substituted 7-acetylamino cephalosporanic acids |
| US7115750B1 (en) * | 1999-09-20 | 2006-10-03 | Takeda Pharmaceutical Company Limited | Melanin concentrating hormone antagonist |
| TR200201023T2 (tr) * | 1999-10-15 | 2002-09-23 | F. Hoffmann-La Roche Ag | Benzodiazepin türevleri. |
| PT1285651E (pt) * | 2000-04-28 | 2010-10-21 | Takeda Pharmaceutical | Antagonistas da hormona concentradora da melanina |
| HUP0302966A2 (hu) * | 2000-07-31 | 2003-12-29 | Smithkline Beecham P.L.C. | Karboxamid-vegyületek és alkalmazásuk humán 11CBY receptor antagonistákként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények |
| GB0124627D0 (en) * | 2001-10-15 | 2001-12-05 | Smithkline Beecham Plc | Novel compounds |
-
2004
- 2004-03-06 DE DE102004010893A patent/DE102004010893A1/de not_active Withdrawn
-
2005
- 2005-03-01 WO PCT/EP2005/002132 patent/WO2005085221A1/de not_active Ceased
- 2005-03-01 CA CA002552907A patent/CA2552907A1/en not_active Abandoned
- 2005-03-01 JP JP2007501195A patent/JP2007527424A/ja active Pending
- 2005-03-01 EP EP05715624A patent/EP1730130A1/de not_active Withdrawn
- 2005-03-04 AR ARP050100829A patent/AR048254A1/es unknown
- 2005-03-04 TW TW094106522A patent/TW200540142A/zh unknown
- 2005-03-04 UY UY28790A patent/UY28790A1/es not_active Application Discontinuation
- 2005-03-04 PE PE2005000250A patent/PE20060001A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PE20060001A1 (es) | 2006-02-03 |
| TW200540142A (en) | 2005-12-16 |
| EP1730130A1 (de) | 2006-12-13 |
| WO2005085221A1 (de) | 2005-09-15 |
| DE102004010893A1 (de) | 2005-09-22 |
| AR048254A1 (es) | 2006-04-12 |
| JP2007527424A (ja) | 2007-09-27 |
| UY28790A1 (es) | 2005-11-30 |
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