CA2547353A1 - Conjugates, and use thereof in detection methods - Google Patents

Conjugates, and use thereof in detection methods Download PDF

Info

Publication number
CA2547353A1
CA2547353A1 CA002547353A CA2547353A CA2547353A1 CA 2547353 A1 CA2547353 A1 CA 2547353A1 CA 002547353 A CA002547353 A CA 002547353A CA 2547353 A CA2547353 A CA 2547353A CA 2547353 A1 CA2547353 A1 CA 2547353A1
Authority
CA
Canada
Prior art keywords
specific binding
analyte
antibody
test
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002547353A
Other languages
English (en)
French (fr)
Inventor
Michael Trier
Carsten Schelp
Harald Ackermann
Lee Hall
Pratap Singh
Susan Swann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/725,166 external-priority patent/US20050118727A1/en
Application filed by Individual filed Critical Individual
Publication of CA2547353A1 publication Critical patent/CA2547353A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002547353A 2003-12-01 2004-11-09 Conjugates, and use thereof in detection methods Abandoned CA2547353A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US52605403P 2003-12-01 2003-12-01
US10/725,166 US20050118727A1 (en) 2003-12-01 2003-12-01 Conjugates and their use in detection methods
US60/526,054 2003-12-01
US10/725,166 2003-12-01
PCT/EP2004/012647 WO2005062057A1 (de) 2003-12-01 2004-11-09 Konjugate und deren verwendung in nachweisverfahren

Publications (1)

Publication Number Publication Date
CA2547353A1 true CA2547353A1 (en) 2005-07-07

Family

ID=34713754

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002547353A Abandoned CA2547353A1 (en) 2003-12-01 2004-11-09 Conjugates, and use thereof in detection methods

Country Status (4)

Country Link
EP (1) EP1692515A1 (https=)
JP (2) JP2007512542A (https=)
CA (1) CA2547353A1 (https=)
WO (1) WO2005062057A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10618056B2 (en) 2007-09-11 2020-04-14 X-Zell Inc. Systems and methods for high gradient magnetic separation of biological material
US11226271B2 (en) 2016-03-07 2022-01-18 X-Zell Biotech Pte Ltd Systems and methods for identifying rare cells
CN114910633A (zh) * 2017-10-26 2022-08-16 科美诊断技术股份有限公司 一种免疫复合物及其应用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004042124B4 (de) * 2004-08-30 2006-07-06 Dade Behring Marburg Gmbh Homogenes Verfahren zur Bestimmung eines Analyten in Gegenwart eines Überschusses von kreuzreagierenden Substanzen
EP1957982A2 (en) * 2005-12-05 2008-08-20 Guava Technologies, Inc. Particle-based analyte characterization
GB201909027D0 (en) * 2019-06-24 2019-08-07 Psyros Diagnostics Ltd A method for detecting an analyte
WO2023095865A1 (ja) * 2021-11-26 2023-06-01 キヤノン株式会社 検体検査用粒子

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434150A (en) * 1981-10-19 1984-02-28 Ortho Diagnostic Systems, Inc. Immunological reagents employing polymeric backbone possessing reactive functional groups
US4778751A (en) * 1986-05-12 1988-10-18 Diagnostic Products Corporation Method for measuring antigens or antibodies in biological fluids using ligand labeled antigens or ligand labeled antibodies
JPH0534346A (ja) * 1990-09-14 1993-02-09 Tosoh Corp 免疫測定法
EP0594772B1 (en) * 1991-07-04 1996-08-28 Immunodex K/S Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone
JP3544962B2 (ja) * 2000-08-21 2004-07-21 エフ．ホフマン−ラ ロシュ アーゲー 改良された結合アッセイ
JP4005338B2 (ja) * 2000-11-29 2007-11-07 ペンタックス株式会社 抗体固相化担体、および、その製造方法
DE10064827A1 (de) * 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
JP2003075443A (ja) * 2001-09-03 2003-03-12 Sekisui Chem Co Ltd 標的物質測定試薬、それを用いた標的物質の測定方法
JP2003194817A (ja) * 2001-12-26 2003-07-09 Techno Network Shikoku Co Ltd イムノクロマトグラフ分析の測定方法
JP4107873B2 (ja) * 2002-05-09 2008-06-25 賢一 花木 発光性微粒子

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10618056B2 (en) 2007-09-11 2020-04-14 X-Zell Inc. Systems and methods for high gradient magnetic separation of biological material
US11226271B2 (en) 2016-03-07 2022-01-18 X-Zell Biotech Pte Ltd Systems and methods for identifying rare cells
US12326386B2 (en) 2016-03-07 2025-06-10 X-Zell, Inc. Systems and methods for identifying rare cells
CN114910633A (zh) * 2017-10-26 2022-08-16 科美诊断技术股份有限公司 一种免疫复合物及其应用

Also Published As

Publication number Publication date
JP2011227102A (ja) 2011-11-10
WO2005062057A1 (de) 2005-07-07
JP2007512542A (ja) 2007-05-17
EP1692515A1 (de) 2006-08-23

Similar Documents

Publication Publication Date Title
CA2365565C (en) Detection methods
AU695419B2 (en) Method for detecting antibodies
AU612907B2 (en) Process and reagent for the determination of a specifically bindable substance
US7105311B2 (en) Systems and methods for detection of analytes in biological fluids
US6303325B1 (en) Method for detecting analytes
US20100248218A1 (en) Conjugates, and use thereof in detection methods
JPH06258325A (ja) 異なる２又は３種類のモノクローナル抗体を使用する 抗原測定法及び該モノクローナル抗体を利用した試験 キット
JPH01227061A (ja) イオン捕捉イムノアッセイ法および装置
US8628933B2 (en) Homogeneous detection method
JP2011227102A (ja) 複合体、及び検出方法におけるそれらの使用
JPH06503886A (ja) 試験方法およびその試薬キット
AU676469B2 (en) Method for the elimination of non-specific reactions in immunoassays
CA1300498C (en) Ice nucleation immunoassay
US20200209230A1 (en) Methods and compositions relating to small molecule analyte assays
US20050118642A1 (en) Homogeneous detection method
AU595899B2 (en) Method for diagnostic immunoassay by solid phase separation
JPH0727764A (ja) Ｆｃ部位をブロックした免疫学的測定用抗体、該抗体を含む免疫学的測定用試薬、該免疫学的測定用試薬を使用する免疫学的測定法及びＦｃ部位をブロックするブロック試薬
Ngo et al. Enzyme Immunoassays Using Tagged Enzyme-Ligand Conjugates

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20131112