CA2546077C - Vaccine and method for treatment of neurodegenerative diseases - Google Patents
Vaccine and method for treatment of neurodegenerative diseases Download PDFInfo
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- A61K39/0007—Nervous system antigens; Prions
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- A61K40/10—Cellular immunotherapy characterised by the cell type used
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- A—HUMAN NECESSITIES
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/22—Immunosuppressive or immunotolerising
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- A—HUMAN NECESSITIES
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US51862703P | 2003-11-12 | 2003-11-12 | |
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| US61096604P | 2004-09-20 | 2004-09-20 | |
| US60/610,966 | 2004-09-20 | ||
| PCT/IL2004/001037 WO2005046719A1 (en) | 2003-11-12 | 2004-11-11 | Vaccine and method for treatment of neurodegenerative diseases |
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| EP (2) | EP1684797A1 (enExample) |
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| CA (1) | CA2546077C (enExample) |
| IL (2) | IL175535A (enExample) |
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| ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| JP5456235B2 (ja) | 2003-11-12 | 2014-03-26 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 神経変性疾患を治療するためのワクチン及び方法 |
| DK1701730T3 (da) | 2003-12-09 | 2013-11-25 | Yeda Res & Dev | Fremgangsmåde og vaccine omfattende copolymer 1 til behandling af psykiatriske forstyrrelser |
| US8193147B2 (en) | 2007-09-24 | 2012-06-05 | Hadasit Medical Research Services & Development Ltd. | Use of copolymer 1 for treatment of muscular dystrophy |
| WO2010019270A1 (en) * | 2008-08-14 | 2010-02-18 | Isis Pharmaceuticals, Inc. | Modulation of prion expression |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| US8759302B2 (en) * | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
| EP2627669B1 (en) | 2010-10-11 | 2016-08-17 | Teva Pharmaceutical Industries Ltd. | Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate |
| WO2012143924A1 (en) | 2011-04-21 | 2012-10-26 | Mapi Pharma Ltd. | Random pentapolymer for treatment of autoimmune diseases |
| US8815511B2 (en) | 2011-10-10 | 2014-08-26 | Teva Pharmaceutical Industries, Ltd. | Determination of single nucleotide polymorphisms useful to predict response for glatiramer acetate |
| WO2013059322A2 (en) * | 2011-10-17 | 2013-04-25 | Lawrence Steinman | Amyloid beta peptide as a therapy for inflammation |
| EP3027205A4 (en) | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| CN106687125B (zh) | 2014-03-12 | 2021-12-14 | 耶达研究与开发有限公司 | 降低系统性调节性t细胞水平或活性来治疗cns疾病和损伤 |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| KR102425326B1 (ko) | 2016-05-20 | 2022-07-25 | 세다르스-신나이 메디칼 센터 | 알츠하이머병 및 관련 병태의 치료 또는 예방 방법 |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| SMT202500136T1 (it) | 2016-08-31 | 2025-05-12 | Mapi Pharma Ltd | Sistemi a deposito comprendenti glatiramer acetato |
| US11167003B2 (en) | 2017-03-26 | 2021-11-09 | Mapi Pharma Ltd. | Methods for suppressing or alleviating primary or secondary progressive multiple sclerosis (PPMS or SPMS) using sustained release glatiramer depot systems |
| TWI841633B (zh) | 2018-11-21 | 2024-05-11 | 美商Ionis製藥公司 | 用於減少朊病毒表現之化合物及方法 |
| EP3725370A1 (en) | 2019-04-19 | 2020-10-21 | ImmunoBrain Checkpoint, Inc. | Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| IL36670A (en) | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
| US6071970A (en) * | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| US5800808A (en) | 1994-05-24 | 1998-09-01 | Veda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
| US6717031B2 (en) | 1995-06-07 | 2004-04-06 | Kate Dora Games | Method for selecting a transgenic mouse model of alzheimer's disease |
| US6794414B1 (en) * | 1998-06-17 | 2004-09-21 | Yeda Research And Development Co. Ltd. | Method and compositions for treating diseases mediated by transglutaminase activity |
| WO2000005249A2 (en) | 1998-07-23 | 2000-02-03 | The President And Fellows Of Harvard College | Synthetic peptides and methods of use for autoimmune disease therapies |
| WO2000005250A1 (en) | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
| EP1248643B1 (en) * | 2000-01-20 | 2005-08-17 | YEDA RESEARCH AND DEVELOPMENT Co. LTD. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
| EP1294390B1 (en) * | 2000-06-07 | 2006-01-04 | YEDA RESEARCH AND DEVELOPMENT CO., Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotection from glutamate toxicity |
| AU6887101A (en) * | 2000-06-20 | 2002-01-02 | Caprion Pharmaceuticals, Inc. | Copolymers and methods of treating prion-related diseases |
| PL211763B1 (pl) * | 2001-05-17 | 2012-06-29 | Serono Lab | Zastosowanie osteopontyny, cząsteczki kwasu nukleinowego, komórki zmodyfikowanej genetycznie oraz kompozycja farmaceutyczna |
| US7718699B1 (en) * | 2005-03-04 | 2010-05-18 | Broyles Robert H | Abscissic acid and derivatives thereof for the treatment of diseases |
| EP1429800B1 (en) | 2001-12-06 | 2009-02-11 | Yeda Research And Development Co., Ltd. | Vaccine and use thereof for treatment of amyotrophic lateral sclerosis |
| JP5456235B2 (ja) | 2003-11-12 | 2014-03-26 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 神経変性疾患を治療するためのワクチン及び方法 |
| US7220729B2 (en) * | 2004-05-10 | 2007-05-22 | Academia Sinica | Huntington's Disease Treatment |
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2004
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- 2004-11-11 EP EP04799345A patent/EP1684797A1/en not_active Withdrawn
- 2004-11-11 WO PCT/IL2004/001037 patent/WO2005046719A1/en not_active Ceased
- 2004-11-11 US US10/578,899 patent/US20080085269A1/en not_active Abandoned
- 2004-11-11 AU AU2004288654A patent/AU2004288654B2/en not_active Ceased
- 2004-11-11 CA CA2546077A patent/CA2546077C/en not_active Expired - Fee Related
- 2004-11-11 EP EP10012062.5A patent/EP2301569B1/en not_active Expired - Lifetime
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2011
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Also Published As
| Publication number | Publication date |
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| JP2007513079A (ja) | 2007-05-24 |
| US20080085269A1 (en) | 2008-04-10 |
| US8828404B2 (en) | 2014-09-09 |
| EP2301569A2 (en) | 2011-03-30 |
| JP5456235B2 (ja) | 2014-03-26 |
| US20110206706A1 (en) | 2011-08-25 |
| EP2301569A3 (en) | 2011-07-06 |
| WO2005046719A1 (en) | 2005-05-26 |
| AU2004288654A1 (en) | 2005-05-26 |
| IL175535A0 (en) | 2006-09-05 |
| IL224393B (en) | 2018-06-28 |
| US20140134196A1 (en) | 2014-05-15 |
| CA2546077A1 (en) | 2005-05-26 |
| IL175535A (en) | 2016-03-31 |
| AU2004288654B2 (en) | 2009-12-03 |
| US9517256B2 (en) | 2016-12-13 |
| EP1684797A1 (en) | 2006-08-02 |
| EP2301569B1 (en) | 2018-05-02 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201112 |