AU2004288654B2 - Vaccine and method for treatment of neurodegenerative diseases - Google Patents
Vaccine and method for treatment of neurodegenerative diseases Download PDFInfo
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- AU2004288654B2 AU2004288654B2 AU2004288654A AU2004288654A AU2004288654B2 AU 2004288654 B2 AU2004288654 B2 AU 2004288654B2 AU 2004288654 A AU2004288654 A AU 2004288654A AU 2004288654 A AU2004288654 A AU 2004288654A AU 2004288654 B2 AU2004288654 B2 AU 2004288654B2
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- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/22—Immunosuppressive or immunotolerising
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/416—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A—HUMAN NECESSITIES
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- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US51862703P | 2003-11-12 | 2003-11-12 | |
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| US61096604P | 2004-09-20 | 2004-09-20 | |
| US60/610,966 | 2004-09-20 | ||
| PCT/IL2004/001037 WO2005046719A1 (en) | 2003-11-12 | 2004-11-11 | Vaccine and method for treatment of neurodegenerative diseases |
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| CA (1) | CA2546077C (enExample) |
| IL (2) | IL175535A (enExample) |
| WO (1) | WO2005046719A1 (enExample) |
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| ES2527760T3 (es) * | 1998-07-23 | 2015-01-29 | Yeda Research And Development Co., Ltd. | Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos |
| EP2301569B1 (en) | 2003-11-12 | 2018-05-02 | Yeda Research and Development Co. Ltd. | Vaccine and method for treatment of neurodegenerative diseases |
| PL1701730T3 (pl) * | 2003-12-09 | 2014-04-30 | Yeda Res & Dev | Sposób i szczepionka zawierająca kopolimer 1 do leczenia zaburzeń psychicznych |
| US8193147B2 (en) | 2007-09-24 | 2012-06-05 | Hadasit Medical Research Services & Development Ltd. | Use of copolymer 1 for treatment of muscular dystrophy |
| WO2010019270A1 (en) * | 2008-08-14 | 2010-02-18 | Isis Pharmaceuticals, Inc. | Modulation of prion expression |
| USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
| US8759302B2 (en) | 2010-03-16 | 2014-06-24 | Teva Pharmaceutical Industries, Ltd. | Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis |
| ES2602977T3 (es) | 2010-10-11 | 2017-02-23 | Teva Pharmaceutical Industries Ltd. | Biomarcadores de citocinas como biomarcadores predictivos de la respuesta clínica para acetato de glatirámero |
| WO2012143924A1 (en) | 2011-04-21 | 2012-10-26 | Mapi Pharma Ltd. | Random pentapolymer for treatment of autoimmune diseases |
| TW201326399A (zh) | 2011-10-10 | 2013-07-01 | Teva Pharma | 用於預測對格拉替雷(glatiramer)醋酸鹽之臨床反應之單核苷酸多型性之判定 |
| WO2013059322A2 (en) * | 2011-10-17 | 2013-04-25 | Lawrence Steinman | Amyloid beta peptide as a therapy for inflammation |
| WO2015017280A1 (en) | 2013-07-28 | 2015-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| ES3040431T3 (en) * | 2014-03-12 | 2025-10-31 | Yeda Res & Dev | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| WO2017201539A1 (en) * | 2016-05-20 | 2017-11-23 | Cedars-Sinai Medical Center | Methods of treating or preventing alzheimer's disease and associated conditions |
| US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
| HRP20250396T1 (hr) | 2016-08-31 | 2025-05-23 | Mapi Pharma Ltd. | Depo sustavi koji sadrže glatiramer acetat |
| AU2018242998B2 (en) | 2017-03-26 | 2023-11-02 | Mapi Pharma Ltd. | Glatiramer depot systems for treating progressive forms of multiple sclerosis |
| MY205095A (en) | 2018-11-21 | 2024-10-01 | Ionis Pharmaceuticals Inc | Compounds and methods for reducing prion expression |
| EP3725370A1 (en) | 2019-04-19 | 2020-10-21 | ImmunoBrain Checkpoint, Inc. | Modified anti-pd-l1 antibodies and methods and uses for treating a neurodegenerative disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001052878A2 (en) * | 2000-01-20 | 2001-07-26 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
| WO2001093893A2 (en) * | 2000-06-07 | 2001-12-13 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL36670A (en) | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
| US6071970A (en) | 1993-02-08 | 2000-06-06 | Nps Pharmaceuticals, Inc. | Compounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases |
| US5800808A (en) | 1994-05-24 | 1998-09-01 | Veda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
| US6717031B2 (en) | 1995-06-07 | 2004-04-06 | Kate Dora Games | Method for selecting a transgenic mouse model of alzheimer's disease |
| US6794414B1 (en) | 1998-06-17 | 2004-09-21 | Yeda Research And Development Co. Ltd. | Method and compositions for treating diseases mediated by transglutaminase activity |
| WO2000005250A1 (en) | 1998-07-23 | 2000-02-03 | Yeda Research And Development Co., Ltd | Treatment of autoimmune conditions with copolymer 1 and related copolymers and peptides |
| JP2003521448A (ja) | 1998-07-23 | 2003-07-15 | ザ・プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 合成ペプチドおよび自己免疫疾患治療のための使用方法 |
| IL148202A0 (en) * | 2000-06-20 | 2002-09-12 | Caprion Pharmaceuticals Inc | Copolymers and methods of treating prion-related diseases |
| WO2002092122A2 (en) | 2001-05-17 | 2002-11-21 | Applied Research Systems Ars Holding N.V. | Use of osteopontin for the treatment and/or prevention of neurologic diseases |
| US7718699B1 (en) | 2005-03-04 | 2010-05-18 | Broyles Robert H | Abscissic acid and derivatives thereof for the treatment of diseases |
| PL205469B1 (pl) | 2001-12-06 | 2010-04-30 | Yeda Res & Dev | Zastosowanie Cop 1 |
| EP2301569B1 (en) | 2003-11-12 | 2018-05-02 | Yeda Research and Development Co. Ltd. | Vaccine and method for treatment of neurodegenerative diseases |
| US7220729B2 (en) | 2004-05-10 | 2007-05-22 | Academia Sinica | Huntington's Disease Treatment |
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2004
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- 2004-11-11 JP JP2006539072A patent/JP5456235B2/ja not_active Expired - Fee Related
- 2004-11-11 EP EP04799345A patent/EP1684797A1/en not_active Withdrawn
- 2004-11-11 AU AU2004288654A patent/AU2004288654B2/en not_active Ceased
- 2004-11-11 US US10/578,899 patent/US20080085269A1/en not_active Abandoned
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2011
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2014
- 2014-01-23 US US14/162,482 patent/US9517256B2/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001052878A2 (en) * | 2000-01-20 | 2001-07-26 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
| WO2001093893A2 (en) * | 2000-06-07 | 2001-12-13 | Yeda Research And Development Co. Ltd. | The use of copolymer 1 and related peptides and polypeptides and t cells treated therewith for neuroprotective therapy |
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| Schwartz. M., Cell and Mol Neurobiol, 2001, Vol. 21, No. 6, pp 617-627 * |
Also Published As
| Publication number | Publication date |
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| EP2301569A2 (en) | 2011-03-30 |
| CA2546077A1 (en) | 2005-05-26 |
| EP1684797A1 (en) | 2006-08-02 |
| US9517256B2 (en) | 2016-12-13 |
| IL175535A (en) | 2016-03-31 |
| IL224393B (en) | 2018-06-28 |
| IL175535A0 (en) | 2006-09-05 |
| AU2004288654A1 (en) | 2005-05-26 |
| WO2005046719A1 (en) | 2005-05-26 |
| US20110206706A1 (en) | 2011-08-25 |
| JP2007513079A (ja) | 2007-05-24 |
| US20140134196A1 (en) | 2014-05-15 |
| CA2546077C (en) | 2016-07-05 |
| US8828404B2 (en) | 2014-09-09 |
| JP5456235B2 (ja) | 2014-03-26 |
| EP2301569A3 (en) | 2011-07-06 |
| EP2301569B1 (en) | 2018-05-02 |
| US20080085269A1 (en) | 2008-04-10 |
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| FGA | Letters patent sealed or granted (standard patent) | ||
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |