CA2536504A1 - Proteines liant l'heparine : capteurs pour la detection de l'heparine - Google Patents
Proteines liant l'heparine : capteurs pour la detection de l'heparine Download PDFInfo
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- CA2536504A1 CA2536504A1 CA002536504A CA2536504A CA2536504A1 CA 2536504 A1 CA2536504 A1 CA 2536504A1 CA 002536504 A CA002536504 A CA 002536504A CA 2536504 A CA2536504 A CA 2536504A CA 2536504 A1 CA2536504 A1 CA 2536504A1
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- heparin
- hbm
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- GDBQQVLCIARPGH-ULQDDVLXSA-N leupeptin Chemical compound CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)CCCN=C(N)N GDBQQVLCIARPGH-ULQDDVLXSA-N 0.000 description 1
- 108010052968 leupeptin Proteins 0.000 description 1
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- 108010009298 lysylglutamic acid Proteins 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
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- 238000007069 methylation reaction Methods 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 238000007837 multiplex assay Methods 0.000 description 1
- 229960000899 nadroparin Drugs 0.000 description 1
- 230000014508 negative regulation of coagulation Effects 0.000 description 1
- HLXZNVUGXRDIFK-UHFFFAOYSA-N nickel titanium Chemical compound [Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ti].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni].[Ni] HLXZNVUGXRDIFK-UHFFFAOYSA-N 0.000 description 1
- 229910001000 nickel titanium Inorganic materials 0.000 description 1
- 231100000065 noncytotoxic Toxicity 0.000 description 1
- 230000002020 noncytotoxic effect Effects 0.000 description 1
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- 238000003199 nucleic acid amplification method Methods 0.000 description 1
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- 239000008188 pellet Substances 0.000 description 1
- 108010091212 pepstatin Proteins 0.000 description 1
- FAXGPCHRFPCXOO-LXTPJMTPSA-N pepstatin A Chemical compound OC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C FAXGPCHRFPCXOO-LXTPJMTPSA-N 0.000 description 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 description 1
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 125000000405 phenylalanyl group Chemical group 0.000 description 1
- 230000026731 phosphorylation Effects 0.000 description 1
- 238000006366 phosphorylation reaction Methods 0.000 description 1
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- 238000013492 plasmid preparation Methods 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 230000010118 platelet activation Effects 0.000 description 1
- 238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
- 229920002851 polycationic polymer Polymers 0.000 description 1
- 229920002704 polyhistidine Polymers 0.000 description 1
- 238000003752 polymerase chain reaction Methods 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001299 polypropylene fumarate Polymers 0.000 description 1
- 230000004481 post-translational protein modification Effects 0.000 description 1
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- 230000003389 potentiating effect Effects 0.000 description 1
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- 230000002035 prolonged effect Effects 0.000 description 1
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- 108060006633 protein kinase Proteins 0.000 description 1
- 238000001742 protein purification Methods 0.000 description 1
- 230000017854 proteolysis Effects 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
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- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 238000010839 reverse transcription Methods 0.000 description 1
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- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- IHQKEDIOMGYHEB-UHFFFAOYSA-M sodium dimethylarsinate Chemical compound [Na+].C[As](C)([O-])=O IHQKEDIOMGYHEB-UHFFFAOYSA-M 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- JQWHASGSAFIOCM-UHFFFAOYSA-M sodium periodate Chemical compound [Na+].[O-]I(=O)(=O)=O JQWHASGSAFIOCM-UHFFFAOYSA-M 0.000 description 1
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- FRGKKTITADJNOE-UHFFFAOYSA-N sulfanyloxyethane Chemical compound CCOS FRGKKTITADJNOE-UHFFFAOYSA-N 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
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- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
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- 229940124597 therapeutic agent Drugs 0.000 description 1
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- 238000012800 visualization Methods 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Materials For Medical Uses (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49449503P | 2003-08-12 | 2003-08-12 | |
US60/494,495 | 2003-08-12 | ||
PCT/US2004/026066 WO2005018552A2 (fr) | 2003-08-12 | 2004-08-12 | Proteines liant l'heparine : capteurs pour la detection de l'heparine |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2536504A1 true CA2536504A1 (fr) | 2005-03-03 |
Family
ID=34215876
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002536504A Abandoned CA2536504A1 (fr) | 2003-08-12 | 2004-08-12 | Proteines liant l'heparine : capteurs pour la detection de l'heparine |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1668359A2 (fr) |
JP (1) | JP2007502112A (fr) |
AU (1) | AU2004266642A1 (fr) |
CA (1) | CA2536504A1 (fr) |
WO (1) | WO2005018552A2 (fr) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8021677B2 (en) | 2006-05-12 | 2011-09-20 | Gore Enterprise Holdings, Inc. | Immobilized biologically active entities having a high degree of biological activity |
US8986713B2 (en) | 2006-05-12 | 2015-03-24 | W. L. Gore & Associates, Inc. | Medical device capable of being compacted and expanded having anti-thrombin III binding activity |
US9114194B2 (en) | 2006-05-12 | 2015-08-25 | W. L. Gore & Associates, Inc. | Immobilized biologically active entities having high biological activity following mechanical manipulation |
US8496953B2 (en) | 2006-05-12 | 2013-07-30 | W. L. Gore & Associates, Inc. | Immobilized biologically active entities having a high degree of biological activity following sterilization |
US8865412B2 (en) | 2008-05-28 | 2014-10-21 | Baxter International Inc. | Methods and assays for oversulfated glycosaminoglycans |
JP5647599B2 (ja) * | 2009-03-02 | 2015-01-07 | 日本たばこ産業株式会社 | 生物学的試料中の物質を検出する方法 |
US8591932B2 (en) * | 2009-09-17 | 2013-11-26 | W. L. Gore & Associates, Inc. | Heparin entities and methods of use |
US9101696B2 (en) | 2011-03-11 | 2015-08-11 | W.L. Gore & Associates, Inc. | Immobilised biological entities |
US10494402B2 (en) | 2012-11-25 | 2019-12-03 | The Regents Of The University Of California | Peptides that stimulate subcutaneous adipogenesis |
WO2015184125A1 (fr) | 2014-05-28 | 2015-12-03 | The Regents Of The University Of California | Peptides, compositions et procédés pour stimuler l'adipogenèse sous-cutanée |
CN113945718A (zh) * | 2020-03-04 | 2022-01-18 | 上海奥普生物医药股份有限公司 | 一种肝素结合蛋白检测试剂盒、制备方法及用途 |
CN114062685B (zh) * | 2021-11-24 | 2023-12-26 | 武汉尚恩生物技术有限公司 | 一种基于elisa双抗体夹心法对细胞种属鉴定的试剂盒 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5182260A (en) * | 1989-01-27 | 1993-01-26 | Biogen, Inc. | Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them |
ES2117050T3 (es) * | 1991-06-27 | 1998-08-01 | Genelabs Tech Inc | Ensayo de cribado para la deteccion de moleculas de union al adn. |
US5792850A (en) * | 1996-05-23 | 1998-08-11 | Zymogenetics, Inc. | Hematopoietic cytokine receptor |
US6200955B1 (en) * | 1996-06-11 | 2001-03-13 | Commonwealth Biotechnologies, Inc. | Heparin binding peptides |
US5843172A (en) * | 1997-04-15 | 1998-12-01 | Advanced Cardiovascular Systems, Inc. | Porous medicated stent |
-
2004
- 2004-08-12 CA CA002536504A patent/CA2536504A1/fr not_active Abandoned
- 2004-08-12 JP JP2006523341A patent/JP2007502112A/ja not_active Withdrawn
- 2004-08-12 EP EP04780840A patent/EP1668359A2/fr not_active Withdrawn
- 2004-08-12 AU AU2004266642A patent/AU2004266642A1/en not_active Abandoned
- 2004-08-12 WO PCT/US2004/026066 patent/WO2005018552A2/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1668359A2 (fr) | 2006-06-14 |
WO2005018552A2 (fr) | 2005-03-03 |
AU2004266642A1 (en) | 2005-03-03 |
WO2005018552A3 (fr) | 2005-07-28 |
JP2007502112A (ja) | 2007-02-08 |
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Legal Events
Date | Code | Title | Description |
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FZDE | Discontinued |