CA2524034A1 - Utilisations de composes modulant les canaux ioniques - Google Patents
Utilisations de composes modulant les canaux ioniques Download PDFInfo
- Publication number
- CA2524034A1 CA2524034A1 CA002524034A CA2524034A CA2524034A1 CA 2524034 A1 CA2524034 A1 CA 2524034A1 CA 002524034 A CA002524034 A CA 002524034A CA 2524034 A CA2524034 A CA 2524034A CA 2524034 A1 CA2524034 A1 CA 2524034A1
- Authority
- CA
- Canada
- Prior art keywords
- ion channel
- channel modulating
- hydrogen
- subject
- modulating compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/12—Oxygen or sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46715903P | 2003-05-02 | 2003-05-02 | |
US60/467,159 | 2003-05-02 | ||
US49339203P | 2003-08-07 | 2003-08-07 | |
US60/493,392 | 2003-08-07 | ||
US51648603P | 2003-10-31 | 2003-10-31 | |
US51624803P | 2003-10-31 | 2003-10-31 | |
US60/516,248 | 2003-10-31 | ||
US60/516,486 | 2003-10-31 | ||
US52691103P | 2003-12-03 | 2003-12-03 | |
US60/526,911 | 2003-12-03 | ||
US52716903P | 2003-12-04 | 2003-12-04 | |
US60/527,169 | 2003-12-04 | ||
US52825103P | 2003-12-08 | 2003-12-08 | |
US60/528,251 | 2003-12-08 | ||
US54494104P | 2004-02-13 | 2004-02-13 | |
US60/544,941 | 2004-02-13 | ||
US55940504P | 2004-04-01 | 2004-04-01 | |
US60/559,405 | 2004-04-01 | ||
PCT/US2004/013731 WO2004098525A2 (fr) | 2003-05-02 | 2004-05-03 | Utilisations de composes modulant les canaux ioniques |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2524034A1 true CA2524034A1 (fr) | 2004-11-18 |
Family
ID=33437324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002524034A Abandoned CA2524034A1 (fr) | 2003-05-02 | 2004-05-03 | Utilisations de composes modulant les canaux ioniques |
Country Status (2)
Country | Link |
---|---|
CA (1) | CA2524034A1 (fr) |
WO (1) | WO2004098525A2 (fr) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK285908B6 (sk) | 1998-04-01 | 2007-10-04 | Nortran Pharmaceuticals Inc. | Aminocyklohexyléterová zlúčenina, kompozícia obsahujúca túto zlúčeninu, použitie tejto zlúčeniny pri výrobe liečiva a pri liečbe |
US7507545B2 (en) | 1999-03-31 | 2009-03-24 | Cardiome Pharma Corp. | Ion channel modulating activity method |
US7524879B2 (en) | 2000-10-06 | 2009-04-28 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
US7057053B2 (en) | 2000-10-06 | 2006-06-06 | Cardiome Pharma Corp. | Ion channel modulating compounds and uses thereof |
US7345086B2 (en) | 2003-05-02 | 2008-03-18 | Cardiome Pharma Corp. | Uses of ion channel modulating compounds |
KR101059379B1 (ko) | 2003-05-02 | 2011-08-26 | 카디오메 파마 코포레이션 | 아미노사이클로헥실 에테르 화합물, 이의 제조방법 및 이를 포함하는 약제학적 조성물 |
US7674820B2 (en) | 2003-08-07 | 2010-03-09 | Cardiome Pharma Corp. | Ion channel modulating activity I |
US7345087B2 (en) | 2003-10-31 | 2008-03-18 | Cardiome Pharma Corp. | Aminocyclohexyl ether compounds and uses thereof |
WO2005094897A2 (fr) * | 2004-04-01 | 2005-10-13 | Cardiome Pharma Corp. | Derives de composes de modulation des canaux ioniques, compositions pharmaceutiques et utilisations |
US8058304B2 (en) | 2004-04-01 | 2011-11-15 | Cardiome Pharma Corp. | Merged ion channel modulating compounds and uses thereof |
EP1729815A2 (fr) | 2004-04-01 | 2006-12-13 | Cardiome Pharma Corp. | Promedicaments de composes modulant les canaux ioniques et leurs utilisations |
US7754897B2 (en) | 2005-06-15 | 2010-07-13 | Cardiome Pharma Corp. | Synthetic processes for the preparation of aminocyclohexyl ether compounds |
US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
US8263638B2 (en) * | 2004-11-08 | 2012-09-11 | Cardiome Pharma Corp. | Dosing regimens for ion channel modulating compounds |
US8692002B2 (en) * | 2004-11-18 | 2014-04-08 | Cardiome Pharma Corp. | Synthetic process for aminocyclohexyl ether compounds |
KR20100017648A (ko) * | 2007-05-04 | 2010-02-16 | 카디오메 파마 코포레이션 | 부정맥을 막기 위한 이온 채널 조절 화합물의 지속 방출성 구강 제형 및 관련 방법 |
WO2009018547A1 (fr) * | 2007-08-01 | 2009-02-05 | Cardiome Pharma Corp. | Formulations à libération prolongée pour la prévention d'arythmies |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2268590A1 (fr) * | 1999-04-12 | 2000-10-12 | Nortran Pharmaceuticals Inc. | Composes de regulation des canaux ioniques et utilisations de ces produits |
-
2004
- 2004-05-03 CA CA002524034A patent/CA2524034A1/fr not_active Abandoned
- 2004-05-03 WO PCT/US2004/013731 patent/WO2004098525A2/fr active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
WO2004098525A2 (fr) | 2004-11-18 |
WO2004098525A9 (fr) | 2005-01-20 |
WO2004098525A3 (fr) | 2005-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |
Effective date: 20190503 |