CA2520930A1 - Utilisation de l'hydrochlorure de la base de principe actif 1-[n2-[3,5-dibromo-n-[[4(3,4-dihydro-2(1h)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-d-tyrosyl]-l-lysyl]-4-(4-pyridinyl)-piperazine en combinaison avec du sumatriptane pour traiter les migraines - Google Patents
Utilisation de l'hydrochlorure de la base de principe actif 1-[n2-[3,5-dibromo-n-[[4(3,4-dihydro-2(1h)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-d-tyrosyl]-l-lysyl]-4-(4-pyridinyl)-piperazine en combinaison avec du sumatriptane pour traiter les migraines Download PDFInfo
- Publication number
- CA2520930A1 CA2520930A1 CA002520930A CA2520930A CA2520930A1 CA 2520930 A1 CA2520930 A1 CA 2520930A1 CA 002520930 A CA002520930 A CA 002520930A CA 2520930 A CA2520930 A CA 2520930A CA 2520930 A1 CA2520930 A1 CA 2520930A1
- Authority
- CA
- Canada
- Prior art keywords
- active substance
- migraine
- hydrochloride
- sumatriptan
- dosage
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229960003708 sumatriptan Drugs 0.000 title claims abstract description 25
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Classifications
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A—HUMAN NECESSITIES
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10314617A DE10314617A1 (de) | 2003-04-01 | 2003-04-01 | Verwendung des Hydrochlorids der Wirkstoffbase 1-[N2-[3,5-Dibrom-N-[[4-(3,4-dihydro-2(1H)-oxochinazolin-3-yl)-1-piperidinyl]-carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazin in Kombination mit Sumatriptan zur Behandlung von Migräne |
| DEDE10314617.2 | 2003-04-01 | ||
| PCT/EP2004/003210 WO2004087134A1 (fr) | 2003-04-01 | 2004-03-26 | Utilisation de l'hydrochlorure de la base de principe actif 1-[n2-[3,5-dibromo-n-[[4 3,4-dihydro-2(1h)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-d-tyrosyl]-l-lysyl]-4-(4-pyridinyl)-piperazine en combinaison avec du sumatriptane pour traiter les migraines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2520930A1 true CA2520930A1 (fr) | 2004-10-14 |
Family
ID=32980861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002520930A Abandoned CA2520930A1 (fr) | 2003-04-01 | 2004-03-26 | Utilisation de l'hydrochlorure de la base de principe actif 1-[n2-[3,5-dibromo-n-[[4(3,4-dihydro-2(1h)-oxoquinazolin-3-yl)-1-piperidinyl]-carbonyl]-d-tyrosyl]-l-lysyl]-4-(4-pyridinyl)-piperazine en combinaison avec du sumatriptane pour traiter les migraines |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1631282A1 (fr) |
| JP (1) | JP2006522044A (fr) |
| AR (1) | AR043793A1 (fr) |
| CA (1) | CA2520930A1 (fr) |
| CL (1) | CL2004000686A1 (fr) |
| DE (1) | DE10314617A1 (fr) |
| TW (1) | TW200501956A (fr) |
| UY (1) | UY28251A1 (fr) |
| WO (1) | WO2004087134A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007533685A (ja) * | 2004-04-20 | 2007-11-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 偏頭痛を治療するためのセロトニン再吸収阻害剤と組合わせたｃｇｒｐアンタゴニストの使用 |
| WO2010046399A1 (fr) * | 2008-10-22 | 2010-04-29 | Novartis Ag | Combinaisons pour le traitement de la migraine |
| WO2017143345A1 (fr) | 2016-02-19 | 2017-08-24 | Zp Opco, Inc. | Procédé pour obtenir rapidement des concentrations thérapeutiques de triptans pour le traitement de migraines |
| US11660264B2 (en) | 2017-08-23 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
| US11660265B2 (en) | 2018-06-28 | 2023-05-30 | Emergex USA Corporation | Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10139410A1 (de) * | 2001-08-17 | 2003-02-27 | Boehringer Ingelheim Pharma | Verwendung von BIBN4096 in Kombination mit anderen Arzneistoffen gegen Migräne für die Behandlung von Migräne |
| DE10206770A1 (de) * | 2002-02-19 | 2003-08-28 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung eines Pulverinhalativums enthaltend ein Salz des CGRP-Antagonisten BIBN4096 |
-
2003
- 2003-04-01 DE DE10314617A patent/DE10314617A1/de not_active Withdrawn
-
2004
- 2004-03-26 CA CA002520930A patent/CA2520930A1/fr not_active Abandoned
- 2004-03-26 WO PCT/EP2004/003210 patent/WO2004087134A1/fr not_active Application Discontinuation
- 2004-03-26 EP EP04723571A patent/EP1631282A1/fr not_active Withdrawn
- 2004-03-26 JP JP2006504871A patent/JP2006522044A/ja active Pending
- 2004-03-30 TW TW093108719A patent/TW200501956A/zh unknown
- 2004-03-30 CL CL200400686A patent/CL2004000686A1/es unknown
- 2004-03-31 AR ARP040101065A patent/AR043793A1/es unknown
- 2004-03-31 UY UY28251A patent/UY28251A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1631282A1 (fr) | 2006-03-08 |
| TW200501956A (en) | 2005-01-16 |
| WO2004087134A1 (fr) | 2004-10-14 |
| AR043793A1 (es) | 2005-08-10 |
| UY28251A1 (es) | 2004-11-08 |
| CL2004000686A1 (es) | 2005-02-04 |
| JP2006522044A (ja) | 2006-09-28 |
| DE10314617A1 (de) | 2004-10-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |