CA2519289A1 - Nemorubicin as radiosensitizer in combination with radiation therapy against tumors - Google Patents
Nemorubicin as radiosensitizer in combination with radiation therapy against tumors Download PDFInfo
- Publication number
- CA2519289A1 CA2519289A1 CA002519289A CA2519289A CA2519289A1 CA 2519289 A1 CA2519289 A1 CA 2519289A1 CA 002519289 A CA002519289 A CA 002519289A CA 2519289 A CA2519289 A CA 2519289A CA 2519289 A1 CA2519289 A1 CA 2519289A1
- Authority
- CA
- Canada
- Prior art keywords
- formula
- radiation therapy
- combined preparation
- morpholinyl
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03075781 | 2003-03-18 | ||
EP03075781.9 | 2003-03-18 | ||
PCT/EP2004/050246 WO2004082579A2 (en) | 2003-03-18 | 2004-03-03 | Nemorubicin as radiosensitizer in combination with radiation therapy against tumors |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2519289A1 true CA2519289A1 (en) | 2004-09-30 |
Family
ID=33016931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002519289A Abandoned CA2519289A1 (en) | 2003-03-18 | 2004-03-03 | Nemorubicin as radiosensitizer in combination with radiation therapy against tumors |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1603575A2 (ru) |
AU (1) | AU2004222526A1 (ru) |
BR (1) | BRPI0408494A (ru) |
CA (1) | CA2519289A1 (ru) |
MX (1) | MXPA05009851A (ru) |
NO (1) | NO20054349L (ru) |
RU (1) | RU2005132175A (ru) |
WO (1) | WO2004082579A2 (ru) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007035489A2 (en) * | 2005-09-16 | 2007-03-29 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of treating or preventing cancer using pyridine carboxaldehyde pyridine thiosemicarbazone radiosensitizing agents |
EP2152236B1 (en) | 2007-05-11 | 2015-09-02 | Nerviano Medical Sciences S.r.l. | Pharmaceutical composition of an anthracycline |
WO2009099741A1 (en) | 2008-02-01 | 2009-08-13 | Genentech, Inc. | Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods |
ES2532635T3 (es) | 2008-07-15 | 2015-03-30 | Genentech, Inc. | Conjugados de antraciclina, proceso para su preparación y su uso como compuestos antitumorales |
CN103270043B (zh) | 2010-12-02 | 2015-12-16 | 内尔维阿诺医学科学有限公司 | 用于制备吗啉基蒽环衍生物的方法 |
WO2016040825A1 (en) | 2014-09-12 | 2016-03-17 | Genentech, Inc. | Anthracycline disulfide intermediates, antibody-drug conjugates and methods |
US20170312290A1 (en) * | 2014-11-05 | 2017-11-02 | Nerviano Medical Sciences S.R.L. | Functionalized morpholinyl anthracycline derivatives |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4710564A (en) * | 1985-01-18 | 1987-12-01 | Microbial Chemistry Research Foundation | Anthracycline compounds |
GB2172594B (en) * | 1985-03-22 | 1988-06-08 | Erba Farmitalia | New morpholino derivatives of daunorubicin and doxorubicin |
GB2296495B (en) * | 1994-12-23 | 1998-04-15 | Erba Carlo Spa | Anthracycline derivatives |
GB2315067B (en) * | 1996-07-11 | 2000-02-16 | Pharmacia Spa | Morpholinyl anthracycline derivatives |
KR100968657B1 (ko) * | 2002-04-02 | 2010-07-06 | 네르비아노 메디칼 사이언시스 에스.알.엘. | 치환된 아크릴로일 디스타마이신 유도체 및 방사선요법을포함하는 조합 종양 치료법 |
-
2004
- 2004-03-03 BR BRPI0408494-2A patent/BRPI0408494A/pt not_active Application Discontinuation
- 2004-03-03 CA CA002519289A patent/CA2519289A1/en not_active Abandoned
- 2004-03-03 MX MXPA05009851A patent/MXPA05009851A/es unknown
- 2004-03-03 RU RU2005132175/15A patent/RU2005132175A/ru not_active Application Discontinuation
- 2004-03-03 EP EP04716607A patent/EP1603575A2/en not_active Withdrawn
- 2004-03-03 AU AU2004222526A patent/AU2004222526A1/en not_active Abandoned
- 2004-03-03 WO PCT/EP2004/050246 patent/WO2004082579A2/en not_active Application Discontinuation
-
2005
- 2005-09-20 NO NO20054349A patent/NO20054349L/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP1603575A2 (en) | 2005-12-14 |
BRPI0408494A (pt) | 2006-04-04 |
AU2004222526A1 (en) | 2004-09-30 |
RU2005132175A (ru) | 2006-01-27 |
NO20054349L (no) | 2005-10-11 |
MXPA05009851A (es) | 2005-12-06 |
WO2004082579A2 (en) | 2004-09-30 |
WO2004082579A3 (en) | 2004-11-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |