MXPA05009851A - Como radiosensibilizador en combinacion con terapia con radiacion contra tumores. - Google Patents

Como radiosensibilizador en combinacion con terapia con radiacion contra tumores.

Info

Publication number
MXPA05009851A
MXPA05009851A MXPA05009851A MXPA05009851A MXPA05009851A MX PA05009851 A MXPA05009851 A MX PA05009851A MX PA05009851 A MXPA05009851 A MX PA05009851A MX PA05009851 A MXPA05009851 A MX PA05009851A MX PA05009851 A MXPA05009851 A MX PA05009851A
Authority
MX
Mexico
Prior art keywords
radiosensitizer
combination
radiation therapy
nemorubicin
against tumors
Prior art date
Application number
MXPA05009851A
Other languages
English (en)
Inventor
Maria Cristina Rosa Geroni
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Publication of MXPA05009851A publication Critical patent/MXPA05009851A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/243—Platinum; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invencion se refiere a un derivado de morfolinil antraciclina para utilizarse como radiosensibilizador, para administrarse en combinacion con terapia con radiacion, de manera que pueda revelarse un efecto sinergistico.
MXPA05009851A 2003-03-18 2004-03-03 Como radiosensibilizador en combinacion con terapia con radiacion contra tumores. MXPA05009851A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03075781 2003-03-18
PCT/EP2004/050246 WO2004082579A2 (en) 2003-03-18 2004-03-03 Nemorubicin as radiosensitizer in combination with radiation therapy against tumors

Publications (1)

Publication Number Publication Date
MXPA05009851A true MXPA05009851A (es) 2005-12-06

Family

ID=33016931

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05009851A MXPA05009851A (es) 2003-03-18 2004-03-03 Como radiosensibilizador en combinacion con terapia con radiacion contra tumores.

Country Status (8)

Country Link
EP (1) EP1603575A2 (es)
AU (1) AU2004222526A1 (es)
BR (1) BRPI0408494A (es)
CA (1) CA2519289A1 (es)
MX (1) MXPA05009851A (es)
NO (1) NO20054349L (es)
RU (1) RU2005132175A (es)
WO (1) WO2004082579A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006292482A1 (en) * 2005-09-16 2007-03-29 Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods of treating or preventing cancer using pyridine carboxaldehyde pyridine thiosemicarbazone radiosensitizing agents
JP5302300B2 (ja) 2007-05-11 2013-10-02 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ アンスラサイクリンの医薬組成物
EP2240495B1 (en) 2008-02-01 2015-07-15 Genentech, Inc. Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
CA2727915C (en) 2008-07-15 2016-04-26 Genentech, Inc. Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
CA2818713C (en) 2010-12-02 2019-03-26 Nerviano Medical Sciences S.R.L. Process for the preparation of morpholinyl anthracycline derivatives
WO2016040825A1 (en) 2014-09-12 2016-03-17 Genentech, Inc. Anthracycline disulfide intermediates, antibody-drug conjugates and methods
US20170312290A1 (en) * 2014-11-05 2017-11-02 Nerviano Medical Sciences S.R.L. Functionalized morpholinyl anthracycline derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
GB2296495B (en) * 1994-12-23 1998-04-15 Erba Carlo Spa Anthracycline derivatives
GB2315067B (en) * 1996-07-11 2000-02-16 Pharmacia Spa Morpholinyl anthracycline derivatives
ATE383154T1 (de) * 2002-04-02 2008-01-15 Nerviano Medical Sciences Srl Kombinierte tumortherapie auf der basis von distamycin-acryloyl derivaten und radiotherapie

Also Published As

Publication number Publication date
AU2004222526A1 (en) 2004-09-30
NO20054349L (no) 2005-10-11
CA2519289A1 (en) 2004-09-30
WO2004082579A3 (en) 2004-11-11
WO2004082579A2 (en) 2004-09-30
EP1603575A2 (en) 2005-12-14
RU2005132175A (ru) 2006-01-27
BRPI0408494A (pt) 2006-04-04

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