CA2508020A1 - Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents - Google Patents

Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents Download PDF

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Publication number
CA2508020A1
CA2508020A1 CA002508020A CA2508020A CA2508020A1 CA 2508020 A1 CA2508020 A1 CA 2508020A1 CA 002508020 A CA002508020 A CA 002508020A CA 2508020 A CA2508020 A CA 2508020A CA 2508020 A1 CA2508020 A1 CA 2508020A1
Authority
CA
Canada
Prior art keywords
compound
effective amount
alkyl
cancer
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002508020A
Other languages
English (en)
French (fr)
Inventor
Nurulain Zaveri
Wan-Ru Chao
Ahlem Bensari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SRI International Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2508020A1 publication Critical patent/CA2508020A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
CA002508020A 2002-12-06 2003-12-08 Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents Abandoned CA2508020A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/313,968 US7122573B2 (en) 2002-12-06 2002-12-06 Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents
US10/313,968 2002-12-06
PCT/US2003/039191 WO2004052873A2 (en) 2002-12-06 2003-12-08 Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents

Publications (1)

Publication Number Publication Date
CA2508020A1 true CA2508020A1 (en) 2004-06-24

Family

ID=32468383

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002508020A Abandoned CA2508020A1 (en) 2002-12-06 2003-12-08 Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents

Country Status (6)

Country Link
US (2) US7122573B2 (enExample)
EP (1) EP1581512A2 (enExample)
JP (1) JP2006510658A (enExample)
AU (1) AU2003297802A1 (enExample)
CA (1) CA2508020A1 (enExample)
WO (1) WO2004052873A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113429371A (zh) * 2021-05-21 2021-09-24 浙江大学 一种原飞燕草素b9没食子酸酯的化学合成方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1767097A3 (en) * 1999-08-16 2007-04-04 DSMIP Assets B.V. Green tea extracts
AU2012200214B2 (en) * 2004-05-14 2013-10-24 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
GB0415181D0 (en) * 2004-07-06 2004-08-11 School Of Pharmacy The Univers Compounds for use in the treatment of infection
JP5265915B2 (ja) * 2004-08-19 2013-08-14 ザ・ホンコン・ポリテクニック・ユニバーシティ プロテアソームを阻害するための（−）−エピガロカテキンガラート誘導体
US8076484B2 (en) 2005-08-11 2011-12-13 Georgia Health Science University Research Institute, Inc. Modified green tea polyphenol formulations
US9446017B2 (en) 2005-08-11 2016-09-20 Augusta University Research Institute, Inc. Compositions and methods for treating herpes simplex virus
JP5128826B2 (ja) * 2007-02-07 2013-01-23 独立行政法人農業・食品産業技術総合研究機構 新規なメチル化カテキン及びそれを含む組成
US20080311252A1 (en) * 2007-06-13 2008-12-18 Selzer Jonathan A Chocolate based dietary supplement product or sweet beverage product
US8945655B2 (en) 2007-07-10 2015-02-03 Conopco, Inc. Stable and consumable compositions
WO2009107262A1 (ja) * 2008-02-25 2009-09-03 学校法人 久留米大学 ３”メチル化エピガロカテキンガレート含有抗癌剤組成物
EP2323648A4 (en) * 2008-08-14 2012-10-03 Uab Research Foundation AGAINST ARTHHYTHMIA, METHOD OF USE, IDENTIFICATION METHOD AND KITS THEREFOR
JP2011162506A (ja) * 2010-02-12 2011-08-25 Tokyo Institute Of Technology エピガロカテキンガレート誘導体及びそれを含む医薬組成物
US8986770B2 (en) 2010-07-30 2015-03-24 Conopco, Inc. Process for fabricating leaf tea products
EA024505B1 (ru) * 2010-07-30 2016-09-30 Унилевер Н.В. Изготовленный из листового чая продукт и способ его получения
US9556140B2 (en) * 2013-01-26 2017-01-31 Sphaera Pharma Pvt. Ltd. Approach for synthesis of catechins
EP3880191A4 (en) * 2018-11-13 2022-08-10 Yee, Amy Compositions and methods of enhancing immunotherapies

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2745305A1 (de) 1977-10-07 1979-04-19 Bayer Ag Insektizide und akarizide mittel
US4255336A (en) * 1977-11-25 1981-03-10 Ciba-Geigy Corporation Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01
KR20010031501A (ko) 1997-10-31 2001-04-16 추후제출 5-알파 환원효소 활성을 조절하는 방법 및 조성물
AU4043900A (en) 1999-03-30 2000-10-16 Purdue Research Foundation Compositions containing tea catechins as cancer specific proliferation inhibitors
JP2001253879A (ja) 2000-03-09 2001-09-18 Shizuoka Prefecture カテキン類のアルキル誘導体
US6713506B2 (en) 2000-10-11 2004-03-30 University Of South Florida Tea polyphenol esters and analogs thereof for cancer prevention and treatment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113429371A (zh) * 2021-05-21 2021-09-24 浙江大学 一种原飞燕草素b9没食子酸酯的化学合成方法
CN113429371B (zh) * 2021-05-21 2022-06-21 浙江大学 一种原飞燕草素b9没食子酸酯的化学合成方法

Also Published As

Publication number Publication date
AU2003297802A1 (en) 2004-06-30
US7122573B2 (en) 2006-10-17
EP1581512A2 (en) 2005-10-05
US20040192723A1 (en) 2004-09-30
US7109236B2 (en) 2006-09-19
JP2006510658A (ja) 2006-03-30
WO2004052873A3 (en) 2005-01-06
WO2004052873A2 (en) 2004-06-24
US20040110790A1 (en) 2004-06-10
AU2003297802A8 (en) 2004-06-30
WO2004052873A9 (en) 2004-08-12

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Legal Events

Date Code Title Description
FZDE Discontinued