JP2006510658A - 化学療法剤および化学予防剤としての緑茶ポリフェノールのアナログ - Google Patents

化学療法剤および化学予防剤としての緑茶ポリフェノールのアナログ Download PDF

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JP2006510658A
JP2006510658A JP2004558631A JP2004558631A JP2006510658A JP 2006510658 A JP2006510658 A JP 2006510658A JP 2004558631 A JP2004558631 A JP 2004558631A JP 2004558631 A JP2004558631 A JP 2004558631A JP 2006510658 A JP2006510658 A JP 2006510658A
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compound
cancer
effective amount
alkyl
hydrogen
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JP2004558631A
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Japanese (ja)
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JP2006510658A5 (enExample
Inventor
ヌルライン ザベリ，
ワン−ル チャオ，
アーレム ベンサリ，
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SRI International Inc
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SRI International Inc
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Publication of JP2006510658A5 publication Critical patent/JP2006510658A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2004558631A 2002-12-06 2003-12-08 化学療法剤および化学予防剤としての緑茶ポリフェノールのアナログ Pending JP2006510658A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/313,968 US7122573B2 (en) 2002-12-06 2002-12-06 Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents
PCT/US2003/039191 WO2004052873A2 (en) 2002-12-06 2003-12-08 Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents

Publications (2)

Publication Number Publication Date
JP2006510658A true JP2006510658A (ja) 2006-03-30
JP2006510658A5 JP2006510658A5 (enExample) 2006-10-26

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ID=32468383

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004558631A Pending JP2006510658A (ja) 2002-12-06 2003-12-08 化学療法剤および化学予防剤としての緑茶ポリフェノールのアナログ

Country Status (6)

Country Link
US (2) US7122573B2 (enExample)
EP (1) EP1581512A2 (enExample)
JP (1) JP2006510658A (enExample)
AU (1) AU2003297802A1 (enExample)
CA (1) CA2508020A1 (enExample)
WO (1) WO2004052873A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009107262A1 (ja) * 2008-02-25 2009-09-03 学校法人 久留米大学 ３”メチル化エピガロカテキンガレート含有抗癌剤組成物
JP2011162506A (ja) * 2010-02-12 2011-08-25 Tokyo Institute Of Technology エピガロカテキンガレート誘導体及びそれを含む医薬組成物

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1767097A3 (en) * 1999-08-16 2007-04-04 DSMIP Assets B.V. Green tea extracts
AU2012200214B2 (en) * 2004-05-14 2013-10-24 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
GB0415181D0 (en) * 2004-07-06 2004-08-11 School Of Pharmacy The Univers Compounds for use in the treatment of infection
JP5265915B2 (ja) * 2004-08-19 2013-08-14 ザ・ホンコン・ポリテクニック・ユニバーシティ プロテアソームを阻害するための（−）−エピガロカテキンガラート誘導体
US8076484B2 (en) 2005-08-11 2011-12-13 Georgia Health Science University Research Institute, Inc. Modified green tea polyphenol formulations
US9446017B2 (en) 2005-08-11 2016-09-20 Augusta University Research Institute, Inc. Compositions and methods for treating herpes simplex virus
JP5128826B2 (ja) * 2007-02-07 2013-01-23 独立行政法人農業・食品産業技術総合研究機構 新規なメチル化カテキン及びそれを含む組成
US20080311252A1 (en) * 2007-06-13 2008-12-18 Selzer Jonathan A Chocolate based dietary supplement product or sweet beverage product
US8945655B2 (en) 2007-07-10 2015-02-03 Conopco, Inc. Stable and consumable compositions
EP2323648A4 (en) * 2008-08-14 2012-10-03 Uab Research Foundation AGAINST ARTHHYTHMIA, METHOD OF USE, IDENTIFICATION METHOD AND KITS THEREFOR
US8986770B2 (en) 2010-07-30 2015-03-24 Conopco, Inc. Process for fabricating leaf tea products
EA024505B1 (ru) * 2010-07-30 2016-09-30 Унилевер Н.В. Изготовленный из листового чая продукт и способ его получения
US9556140B2 (en) * 2013-01-26 2017-01-31 Sphaera Pharma Pvt. Ltd. Approach for synthesis of catechins
EP3880191A4 (en) * 2018-11-13 2022-08-10 Yee, Amy Compositions and methods of enhancing immunotherapies
CN113429371B (zh) * 2021-05-21 2022-06-21 浙江大学 一种原飞燕草素b9没食子酸酯的化学合成方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999022728A1 (en) * 1997-10-31 1999-05-14 Arch Development Corporation Methods and compositions for regulation of 5-alpha reductase activity
JP2001253879A (ja) * 2000-03-09 2001-09-18 Shizuoka Prefecture カテキン類のアルキル誘導体
US20020151582A1 (en) * 2000-10-11 2002-10-17 Dou Q. Ping Tea polyphenol esters and analogs thereof for cancer prevention and treatment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2745305A1 (de) 1977-10-07 1979-04-19 Bayer Ag Insektizide und akarizide mittel
US4255336A (en) * 1977-11-25 1981-03-10 Ciba-Geigy Corporation Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01
AU4043900A (en) 1999-03-30 2000-10-16 Purdue Research Foundation Compositions containing tea catechins as cancer specific proliferation inhibitors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999022728A1 (en) * 1997-10-31 1999-05-14 Arch Development Corporation Methods and compositions for regulation of 5-alpha reductase activity
JP2001253879A (ja) * 2000-03-09 2001-09-18 Shizuoka Prefecture カテキン類のアルキル誘導体
US20020151582A1 (en) * 2000-10-11 2002-10-17 Dou Q. Ping Tea polyphenol esters and analogs thereof for cancer prevention and treatment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009107262A1 (ja) * 2008-02-25 2009-09-03 学校法人 久留米大学 ３”メチル化エピガロカテキンガレート含有抗癌剤組成物
JP2011162506A (ja) * 2010-02-12 2011-08-25 Tokyo Institute Of Technology エピガロカテキンガレート誘導体及びそれを含む医薬組成物

Also Published As

Publication number Publication date
AU2003297802A1 (en) 2004-06-30
CA2508020A1 (en) 2004-06-24
US7122573B2 (en) 2006-10-17
EP1581512A2 (en) 2005-10-05
US20040192723A1 (en) 2004-09-30
US7109236B2 (en) 2006-09-19
WO2004052873A3 (en) 2005-01-06
WO2004052873A2 (en) 2004-06-24
US20040110790A1 (en) 2004-06-10
AU2003297802A8 (en) 2004-06-30
WO2004052873A9 (en) 2004-08-12

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