CA2505949A1 - Process for designing inhibitors of influenza virus non-structural protein 1 - Google Patents
Process for designing inhibitors of influenza virus non-structural protein 1 Download PDFInfo
- Publication number
- CA2505949A1 CA2505949A1 CA002505949A CA2505949A CA2505949A1 CA 2505949 A1 CA2505949 A1 CA 2505949A1 CA 002505949 A CA002505949 A CA 002505949A CA 2505949 A CA2505949 A CA 2505949A CA 2505949 A1 CA2505949 A1 CA 2505949A1
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- Prior art keywords
- dsrna
- protein
- influenza virus
- ns1a
- compound
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42566102P | 2002-11-13 | 2002-11-13 | |
| US60/425,661 | 2002-11-13 | ||
| US47745303P | 2003-06-10 | 2003-06-10 | |
| US60/477,453 | 2003-06-10 | ||
| PCT/US2003/036292 WO2004043404A2 (en) | 2002-11-13 | 2003-11-13 | Process for designing inhibitors of influenza virus non-structural protein 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2505949A1 true CA2505949A1 (en) | 2004-05-27 |
Family
ID=32314599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002505949A Abandoned CA2505949A1 (en) | 2002-11-13 | 2003-11-13 | Process for designing inhibitors of influenza virus non-structural protein 1 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20080234175A1 (https=) |
| JP (1) | JP2006506101A (https=) |
| AU (1) | AU2003290842A1 (https=) |
| CA (1) | CA2505949A1 (https=) |
| WO (1) | WO2004043404A2 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP4837827B2 (ja) | 1998-06-12 | 2011-12-14 | マウント シナイ スクール オブ メディシン | 新規なウイルス増殖方法およびそのためのインターフェロン欠損培養基 |
| WO2001077394A1 (en) | 2000-04-10 | 2001-10-18 | Mount Sinai School Of Medicine Of New York University | Screening methods for identifying viral proteins with interferon antagonizing functions and potential antiviral agents |
| DK2497492T3 (en) | 2004-06-01 | 2018-11-26 | Icahn School Med Mount Sinai | Genetically modified swine influenza virus and its applications |
| WO2006088481A2 (en) * | 2005-02-15 | 2006-08-24 | Mount Sinai School Of Medicine Of New York University | Genetically engineered equine influenza virus and uses thereof |
| EP1948796A1 (en) * | 2005-11-07 | 2008-07-30 | Dow Gloval Technologies Inc. | Process for the preparation of nucleic acid duplexes |
| US9119810B2 (en) | 2005-11-18 | 2015-09-01 | Rutgers, The State University Of New Jersey | Compositions and vaccines against influenza A and influenza B infections |
| US7709190B2 (en) | 2005-12-02 | 2010-05-04 | Board Of Regents, The University Of Texas System | Influenza A virus vaccines and inhibitors |
| US7601490B2 (en) | 2005-12-02 | 2009-10-13 | Board Of Regents, The University Of Texas System | Development of influenza A antivirals |
| CN102002489B (zh) * | 2009-09-02 | 2013-06-12 | 中国科学院微生物研究所 | 抑制H1N1型流感病毒增殖的microRNA及其应用 |
| WO2011147199A1 (en) * | 2010-05-28 | 2011-12-01 | Versitech Limited | Compounds and methods for treating viral infections |
| KR101471245B1 (ko) * | 2012-05-31 | 2014-12-10 | 충북대학교 산학협력단 | Ａ형 인플루엔자 바이러스 감염 질환의 예방 및 치료용 조성물 |
| KR20170122786A (ko) | 2015-02-26 | 2017-11-06 | 베링거잉겔하임베트메디카게엠베하 | 2가 돼지 인플루엔자 바이러스 백신 |
| JP2024536360A (ja) * | 2021-10-06 | 2024-10-04 | セキラス インコーポレイテッド | 核酸結合タンパク質を含む脂質ナノ粒子 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5750394A (en) * | 1994-05-20 | 1998-05-12 | The Mount Sinai Medical Center | Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication |
| US5843724A (en) * | 1995-04-27 | 1998-12-01 | Rutgers University | Chimeric nucleic acids and proteins for inhibiting HIV-1 expression |
| CN1278921A (zh) * | 1997-09-12 | 2001-01-03 | 基因实验室公司 | dsRNA/dsRNA结合蛋白方法及组合物 |
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2003
- 2003-11-13 JP JP2005507162A patent/JP2006506101A/ja active Pending
- 2003-11-13 AU AU2003290842A patent/AU2003290842A1/en not_active Abandoned
- 2003-11-13 US US10/534,782 patent/US20080234175A1/en not_active Abandoned
- 2003-11-13 CA CA002505949A patent/CA2505949A1/en not_active Abandoned
- 2003-11-13 WO PCT/US2003/036292 patent/WO2004043404A2/en not_active Ceased
-
2009
- 2009-09-11 US US12/557,927 patent/US20100081126A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003290842A1 (en) | 2004-06-03 |
| US20080234175A1 (en) | 2008-09-25 |
| US20100081126A1 (en) | 2010-04-01 |
| AU2003290842A8 (en) | 2004-06-03 |
| WO2004043404A3 (en) | 2004-09-23 |
| JP2006506101A (ja) | 2006-02-23 |
| WO2004043404A2 (en) | 2004-05-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20170517 |