AU2003290842A1 - Process for designing inhibitors of influenza virus non-structural protein 1 - Google Patents

Process for designing inhibitors of influenza virus non-structural protein 1

Info

Publication number
AU2003290842A1
AU2003290842A1 AU2003290842A AU2003290842A AU2003290842A1 AU 2003290842 A1 AU2003290842 A1 AU 2003290842A1 AU 2003290842 A AU2003290842 A AU 2003290842A AU 2003290842 A AU2003290842 A AU 2003290842A AU 2003290842 A1 AU2003290842 A1 AU 2003290842A1
Authority
AU
Australia
Prior art keywords
influenza virus
structural protein
virus non
designing inhibitors
designing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003290842A
Other languages
English (en)
Other versions
AU2003290842A8 (en
Inventor
Robert M. Krug
Gaetano T. Montelione
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers State University of New Jersey
Original Assignee
Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers State University of New Jersey filed Critical Rutgers State University of New Jersey
Publication of AU2003290842A8 publication Critical patent/AU2003290842A8/xx
Publication of AU2003290842A1 publication Critical patent/AU2003290842A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16211—Influenzavirus B, i.e. influenza B virus
    • C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU2003290842A 2002-11-13 2003-11-13 Process for designing inhibitors of influenza virus non-structural protein 1 Abandoned AU2003290842A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42566102P 2002-11-13 2002-11-13
US60/425,661 2002-11-13
US47745303P 2003-06-10 2003-06-10
US60/477,453 2003-06-10
PCT/US2003/036292 WO2004043404A2 (en) 2002-11-13 2003-11-13 Process for designing inhibitors of influenza virus non-structural protein 1

Publications (2)

Publication Number Publication Date
AU2003290842A8 AU2003290842A8 (en) 2004-06-03
AU2003290842A1 true AU2003290842A1 (en) 2004-06-03

Family

ID=32314599

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003290842A Abandoned AU2003290842A1 (en) 2002-11-13 2003-11-13 Process for designing inhibitors of influenza virus non-structural protein 1

Country Status (5)

Country Link
US (2) US20080234175A1 (https=)
JP (1) JP2006506101A (https=)
AU (1) AU2003290842A1 (https=)
CA (1) CA2505949A1 (https=)
WO (1) WO2004043404A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100637937B1 (ko) 1998-06-12 2006-10-23 마운트 시나이 스쿨 오브 메디신 오브 뉴욕 유니버시티 변형된 인터페론 길항물질을 보유하고, 백신 및 약제로사용되는 약독화된 네거티브 가닥 바이러스
WO2001077394A1 (en) 2000-04-10 2001-10-18 Mount Sinai School Of Medicine Of New York University Screening methods for identifying viral proteins with interferon antagonizing functions and potential antiviral agents
EP3332803B1 (en) 2004-06-01 2021-09-08 Icahn School of Medicine at Mount Sinai Genetically engineered swine influenza virus and uses thereof
WO2006088481A2 (en) * 2005-02-15 2006-08-24 Mount Sinai School Of Medicine Of New York University Genetically engineered equine influenza virus and uses thereof
US20090221808A1 (en) * 2005-11-07 2009-09-03 Fazio Michael J Process for the Preparation of Nucleic Acid Duplexes
US9119810B2 (en) 2005-11-18 2015-09-01 Rutgers, The State University Of New Jersey Compositions and vaccines against influenza A and influenza B infections
US7709190B2 (en) 2005-12-02 2010-05-04 Board Of Regents, The University Of Texas System Influenza A virus vaccines and inhibitors
US7601490B2 (en) 2005-12-02 2009-10-13 Board Of Regents, The University Of Texas System Development of influenza A antivirals
CN102002489B (zh) * 2009-09-02 2013-06-12 中国科学院微生物研究所 抑制H1N1型流感病毒增殖的microRNA及其应用
WO2011147199A1 (en) * 2010-05-28 2011-12-01 Versitech Limited Compounds and methods for treating viral infections
KR101471245B1 (ko) * 2012-05-31 2014-12-10 충북대학교 산학협력단 Ａ형 인플루엔자 바이러스 감염 질환의 예방 및 치료용 조성물
JP6722686B2 (ja) 2015-02-26 2020-07-15 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ 二価ブタインフルエンザウイルスワクチン
JP2024536360A (ja) * 2021-10-06 2024-10-04 セキラス インコーポレイテッド 核酸結合タンパク質を含む脂質ナノ粒子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750394A (en) * 1994-05-20 1998-05-12 The Mount Sinai Medical Center Identification and use of antiviral compounds that inhibit interaction of host cell proteins and viral proteins required for viral replication
US5843724A (en) * 1995-04-27 1998-12-01 Rutgers University Chimeric nucleic acids and proteins for inhibiting HIV-1 expression
JP2001516058A (ja) * 1997-09-12 2001-09-25 ジェネラブス テクノロジーズ，インコーポレイテッド ｄｓＲＮＡ／ｄｓＲＮＡ結合タンパク質の方法および組成物

Also Published As

Publication number Publication date
AU2003290842A8 (en) 2004-06-03
WO2004043404A2 (en) 2004-05-27
US20080234175A1 (en) 2008-09-25
JP2006506101A (ja) 2006-02-23
CA2505949A1 (en) 2004-05-27
US20100081126A1 (en) 2010-04-01
WO2004043404A3 (en) 2004-09-23

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase