CA2505403A1 - Modified dendritic cells - Google Patents
Modified dendritic cells Download PDFInfo
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- CA2505403A1 CA2505403A1 CA002505403A CA2505403A CA2505403A1 CA 2505403 A1 CA2505403 A1 CA 2505403A1 CA 002505403 A CA002505403 A CA 002505403A CA 2505403 A CA2505403 A CA 2505403A CA 2505403 A1 CA2505403 A1 CA 2505403A1
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5418—IL-7
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/11—Antisense
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15041—Use of virus, viral particle or viral elements as a vector
- C12N2740/15043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
- C12N2840/206—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES having multiple IRES
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42460202P | 2002-11-07 | 2002-11-07 | |
| US60/424,602 | 2002-11-07 | ||
| PCT/US2003/035482 WO2004044147A2 (en) | 2002-11-07 | 2003-11-07 | Modified dendritic cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2505403A1 true CA2505403A1 (en) | 2004-05-27 |
Family
ID=32312839
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002505403A Abandoned CA2505403A1 (en) | 2002-11-07 | 2003-11-07 | Modified dendritic cells |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060013803A1 (enExample) |
| EP (1) | EP1562635A4 (enExample) |
| JP (1) | JP2006505280A (enExample) |
| CN (1) | CN1708320A (enExample) |
| AU (1) | AU2003287557A1 (enExample) |
| CA (1) | CA2505403A1 (enExample) |
| WO (1) | WO2004044147A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090010948A1 (en) * | 2006-12-15 | 2009-01-08 | The University Of Hong Kong | Anti-tumor vaccines delivered by dendritic cells devoid of interleukin-10 |
| ES2636460T3 (es) * | 2007-10-08 | 2017-10-05 | Intrexon Corporation | Células dendríticas modificadas por ingeniería y usos para el tratamiento del cáncer |
| CN105683392A (zh) * | 2013-03-15 | 2016-06-15 | 博德研究所 | 树突细胞应答基因表达、物质组合物及其使用方法 |
| CN103834691B (zh) * | 2014-01-21 | 2016-06-29 | 宁波大学 | 靶向il-33基因rna干扰重组慢病毒载体的构建方法 |
| KR20180073586A (ko) * | 2015-11-09 | 2018-07-02 | 이뮨 디자인 코포레이션 | Il-12를 발현하는 렌티바이러스 벡터를 포함하는 조성물 및 이를 이용한 방법 |
| CN108676815A (zh) * | 2018-05-31 | 2018-10-19 | 深圳市免疫基因治疗研究院 | 一种b型血友病慢病毒载体、慢病毒及其制备方法和应用 |
| CN111647563A (zh) * | 2020-08-06 | 2020-09-11 | 北京翊博普惠生物科技发展有限公司 | 靶向Survivin全抗原的DC细胞、CTL细胞及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5965535A (en) * | 1997-09-12 | 1999-10-12 | Ludwig Institute For Cancer Research | Mage-3 peptides presented by HLA class II molecules |
| JP2000004883A (ja) * | 1998-06-24 | 2000-01-11 | Hisamitsu Pharmaceut Co Inc | Ｉｌ−１０蛋白の発現を阻害するアンチセンスオリゴヌクレオチド |
| DE19956568A1 (de) * | 1999-01-30 | 2000-08-17 | Roland Kreutzer | Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens |
| CA2760534A1 (en) * | 1999-04-14 | 2000-10-19 | Novartis Vaccines And Diagnostics, Inc. | Compositions and methods for generating an immune response utilizing alphavirus-based vector systems |
| EP1214437A1 (en) * | 1999-08-27 | 2002-06-19 | The Regents of the University of California | Use of lentiviral vectors for antigen presentation in dendritic cells |
| US6627442B1 (en) * | 2000-08-31 | 2003-09-30 | Virxsys Corporation | Methods for stable transduction of cells with hiv-derived viral vectors |
| GB0130955D0 (en) * | 2001-12-24 | 2002-02-13 | Cancer Res Ventures | Expression system |
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2003
- 2003-11-07 CA CA002505403A patent/CA2505403A1/en not_active Abandoned
- 2003-11-07 JP JP2004551842A patent/JP2006505280A/ja active Pending
- 2003-11-07 WO PCT/US2003/035482 patent/WO2004044147A2/en not_active Ceased
- 2003-11-07 CN CN200380102586.2A patent/CN1708320A/zh active Pending
- 2003-11-07 EP EP03781799A patent/EP1562635A4/en not_active Withdrawn
- 2003-11-07 AU AU2003287557A patent/AU2003287557A1/en not_active Abandoned
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2005
- 2005-05-05 US US11/122,456 patent/US20060013803A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004044147A3 (en) | 2004-09-10 |
| WO2004044147A2 (en) | 2004-05-27 |
| CN1708320A (zh) | 2005-12-14 |
| US20060013803A1 (en) | 2006-01-19 |
| EP1562635A4 (en) | 2007-12-19 |
| EP1562635A2 (en) | 2005-08-17 |
| AU2003287557A1 (en) | 2004-06-03 |
| JP2006505280A (ja) | 2006-02-16 |
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