CA2505216C - Method and apparatus for dispensing a liquid with a pipetting needle - Google Patents

Method and apparatus for dispensing a liquid with a pipetting needle Download PDF

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Publication number
CA2505216C
CA2505216C CA2505216A CA2505216A CA2505216C CA 2505216 C CA2505216 C CA 2505216C CA 2505216 A CA2505216 A CA 2505216A CA 2505216 A CA2505216 A CA 2505216A CA 2505216 C CA2505216 C CA 2505216C
Authority
CA
Canada
Prior art keywords
needle
pipetting needle
tip
pipetting
pulse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2505216A
Other languages
English (en)
French (fr)
Other versions
CA2505216A1 (en
Inventor
Juerg Dual
Olivier Elsenhans
Frank May
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2505216A1 publication Critical patent/CA2505216A1/en
Application granted granted Critical
Publication of CA2505216C publication Critical patent/CA2505216C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0433—Moving fluids with specific forces or mechanical means specific forces vibrational forces
    • B01L2400/0439—Moving fluids with specific forces or mechanical means specific forces vibrational forces ultrasonic vibrations, vibrating piezo elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1039—Micropipettes, e.g. microcapillary tubes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
CA2505216A 2004-05-14 2005-04-26 Method and apparatus for dispensing a liquid with a pipetting needle Expired - Fee Related CA2505216C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04076436.7 2004-05-14
EP04076436A EP1604741A1 (en) 2004-05-14 2004-05-14 Method and apparatus for dispensing a liquid with a pipetting needle

Publications (2)

Publication Number Publication Date
CA2505216A1 CA2505216A1 (en) 2005-11-14
CA2505216C true CA2505216C (en) 2010-01-26

Family

ID=34928221

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2505216A Expired - Fee Related CA2505216C (en) 2004-05-14 2005-04-26 Method and apparatus for dispensing a liquid with a pipetting needle

Country Status (7)

Country Link
US (1) US7615378B2 (cg-RX-API-DMAC7.html)
EP (1) EP1604741A1 (cg-RX-API-DMAC7.html)
JP (1) JP4602154B2 (cg-RX-API-DMAC7.html)
AT (1) ATE373519T1 (cg-RX-API-DMAC7.html)
CA (1) CA2505216C (cg-RX-API-DMAC7.html)
DE (1) DE602005002499T2 (cg-RX-API-DMAC7.html)
ES (1) ES2293472T3 (cg-RX-API-DMAC7.html)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010001229A1 (de) * 2010-01-26 2011-07-28 Hamilton Bonaduz Ag Verfahren und Vorrichtung zur Bestimmung eines flüssigkeitsspezifischen oder vom Benetzungszustand einer Pipettierspitze abhängigen Parameters durch Schwingungsanregung
EP2637780B1 (en) 2010-11-12 2022-02-09 Gen9, Inc. Protein arrays and methods of using and making the same
DK2665557T3 (da) 2011-01-21 2020-04-06 Biodot Inc Piezoelektrisk dispenser med en langsgående transducer og udskifteligt kapillærrør
US20130206857A1 (en) * 2011-01-21 2013-08-15 Biodot, Inc. Piezoelectric dispenser with a longitudinal transducer and replaceable capillary tube
ES2737957T3 (es) 2011-08-26 2020-01-17 Gen9 Inc Composiciones y métodos para el ensamblaje de alta fidelidad de ácidos nucleicos
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
EP4001427A1 (en) 2012-04-24 2022-05-25 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
CN103472243B (zh) * 2012-06-06 2016-08-03 北京普源精仪科技有限责任公司 一种自动进样器及取样针
CN110691868A (zh) * 2017-05-22 2020-01-14 Gen9股份有限公司 用于核酸操纵的装置和方法
CN110064453B (zh) * 2018-01-24 2024-04-16 思纳福(苏州)生命科技有限公司 微液滴生成装置及生成方法
CN109908986B (zh) * 2019-02-21 2020-04-28 浙江大学 一种基于出口不对称毛细管的液滴生成系统及使用方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4974458A (en) * 1987-12-14 1990-12-04 Ajinomoto Company, Inc. Automatic preparation apparatus and support arm
JPH0781996B2 (ja) * 1988-08-27 1995-09-06 株式会社日立製作所 オートサンプラ
US5582798A (en) * 1995-02-23 1996-12-10 Cyberlab Inc. Volume sensing device
JPH08338849A (ja) * 1995-04-11 1996-12-24 Precision Syst Sci Kk 液体の吸引判別方法およびこの方法により駆動制御される分注装置
US5750881A (en) * 1995-07-13 1998-05-12 Chiron Diagnostics Corporation Method and apparatus for aspirating and dispensing sample fluids
JP3341023B2 (ja) * 1995-08-07 2002-11-05 オムロン株式会社 表面弾性波を利用した噴霧装置および噴霧方法
US6003388A (en) * 1997-09-17 1999-12-21 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration System for manipulating drops and bubbles using acoustic radiation pressure
US6296811B1 (en) * 1998-12-10 2001-10-02 Aurora Biosciences Corporation Fluid dispenser and dispensing methods
US6232129B1 (en) * 1999-02-03 2001-05-15 Peter Wiktor Piezoelectric pipetting device
EP1207396A1 (fr) * 2000-10-20 2002-05-22 Seyonic SA Dispositif dispensateur de fluide
CH695544A5 (de) * 2000-11-17 2006-06-30 Tecan Trading Ag Vorrichtung zur Abgabe bzw. Aufnahme/Abgabe von Flüssigkeitsproben.
WO2002070133A1 (en) * 2001-03-01 2002-09-12 Peter Wiktor Piezoelectric pipetting device housing and methods for making and using the same
JP2003050244A (ja) * 2001-08-07 2003-02-21 Matsushita Electric Ind Co Ltd 分注機
JP3673782B2 (ja) * 2002-09-25 2005-07-20 キヤノン株式会社 液体吐出ヘッド、液体吐出ヘッドの駆動方法、および液体吐出装置
US7097810B2 (en) * 2002-06-26 2006-08-29 The Public Health Research Institute Of The City Of New York, Inc. Delivery of metered amounts of liquid materials
US6874699B2 (en) * 2002-10-15 2005-04-05 Wisconsin Alumni Research Foundation Methods and apparata for precisely dispensing microvolumes of fluids
US7125727B2 (en) * 2003-01-29 2006-10-24 Protedyne Corporation Sample handling tool with piezoelectric actuator
US7396512B2 (en) * 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US7258480B2 (en) * 2005-01-10 2007-08-21 Dade Behring Inc. Apparatus for mixing liquid samples using a two dimensional stirring pattern

Also Published As

Publication number Publication date
ATE373519T1 (de) 2007-10-15
ES2293472T3 (es) 2008-03-16
JP4602154B2 (ja) 2010-12-22
DE602005002499D1 (de) 2007-10-31
US20060286678A1 (en) 2006-12-21
JP2005326421A (ja) 2005-11-24
US7615378B2 (en) 2009-11-10
CA2505216A1 (en) 2005-11-14
DE602005002499T2 (de) 2008-06-19
EP1604741A1 (en) 2005-12-14

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Legal Events

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EEER Examination request
MKLA Lapsed

Effective date: 20210426