CA2504932A1 - Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease - Google Patents

Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease Download PDF

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Publication number
CA2504932A1
CA2504932A1 CA002504932A CA2504932A CA2504932A1 CA 2504932 A1 CA2504932 A1 CA 2504932A1 CA 002504932 A CA002504932 A CA 002504932A CA 2504932 A CA2504932 A CA 2504932A CA 2504932 A1 CA2504932 A1 CA 2504932A1
Authority
CA
Canada
Prior art keywords
botulinum toxin
reflux disease
gastroesophageal reflux
oral formulation
peptic ulcers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002504932A
Other languages
English (en)
French (fr)
Inventor
Richard L. Barron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2504932A1 publication Critical patent/CA2504932A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A61K38/4893—Botulinum neurotoxin (3.4.24.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
CA002504932A 2002-11-05 2003-11-03 Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease Abandoned CA2504932A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/288,734 US7238357B2 (en) 2002-11-05 2002-11-05 Methods for treating ulcers and gastroesophageal reflux disease
US10/288,734 2002-11-05
PCT/US2003/035199 WO2004041303A1 (en) 2002-11-05 2003-11-03 Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease

Publications (1)

Publication Number Publication Date
CA2504932A1 true CA2504932A1 (en) 2004-05-21

Family

ID=32175959

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002504932A Abandoned CA2504932A1 (en) 2002-11-05 2003-11-03 Oral formulation or botulinum toxin and use thereof for treating peptic ulcers and gastroesophageal reflux disease

Country Status (15)

Country Link
US (1) US7238357B2 (https=)
EP (1) EP1558279B1 (https=)
JP (1) JP4808404B2 (https=)
KR (1) KR101072179B1 (https=)
CN (1) CN100349613C (https=)
AT (1) ATE454162T1 (https=)
AU (1) AU2003286901B2 (https=)
BR (1) BR0315979A (https=)
CA (1) CA2504932A1 (https=)
DE (1) DE60330889D1 (https=)
DK (1) DK1558279T3 (https=)
ES (1) ES2337892T3 (https=)
MX (1) MXPA05004629A (https=)
NZ (1) NZ539170A (https=)
WO (1) WO2004041303A1 (https=)

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US20060073208A1 (en) 2004-10-01 2006-04-06 Allergan, Inc. Cosmetic neurotoxin compositions and methods
EP1871789B1 (en) 2005-03-15 2013-11-06 Allergan, Inc. Modified clostridial toxins with altered targeting capabilities for clostridial toxin target cells
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US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
US8470337B2 (en) * 2008-03-13 2013-06-25 Allergan, Inc. Therapeutic treatments using botulinum neurotoxin
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US8506970B2 (en) * 2008-10-14 2013-08-13 Dt Scimed, Llc Dose and localization of botulinum toxins in skin and muscle
WO2010096134A1 (en) 2008-12-04 2010-08-26 Botulinum Toxin Research Associates, Inc. Extended length botulinum toxin formulation for human or mammalian use
US9858831B2 (en) 2009-02-15 2018-01-02 Cheryl L. Evans Method for determining and prescribing quantifiable and customized diet for patient suffering from dysphagia
US8936471B2 (en) * 2009-02-15 2015-01-20 Cheryl L. Evans Flow rate measuring device
US8753124B2 (en) * 2009-02-15 2014-06-17 Cheryl Lynn Evans Method and apparatus for prescribing and preparing a reproducible and customized dysphagia diet
WO2011038015A1 (en) 2009-09-24 2011-03-31 Allergan, Inc. Method of treating osteoporosis with a neurotoxin
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US20120244188A1 (en) * 2011-03-25 2012-09-27 Allergan, Inc. Treatment of Sensory Disturbance Disorders
US8697090B2 (en) 2011-05-05 2014-04-15 Allergan, Inc. Method of treating persistent genital arousal disorder with a neurotoxin
US9393291B2 (en) 2012-04-12 2016-07-19 Botulinum Toxin Research Associates, Inc. Use of botulinum toxin for the treatment of cerebrovascular disease, renovascular and retinovascular circulatory beds
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US9901627B2 (en) 2014-07-18 2018-02-27 Revance Therapeutics, Inc. Topical ocular preparation of botulinum toxin for use in ocular surface disease
US11484580B2 (en) 2014-07-18 2022-11-01 Revance Therapeutics, Inc. Topical ocular preparation of botulinum toxin for use in ocular surface disease
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Also Published As

Publication number Publication date
KR20050084657A (ko) 2005-08-26
JP4808404B2 (ja) 2011-11-02
WO2004041303A1 (en) 2004-05-21
US20040086531A1 (en) 2004-05-06
NZ539170A (en) 2007-08-31
MXPA05004629A (es) 2005-06-08
CN100349613C (zh) 2007-11-21
DK1558279T3 (da) 2010-05-03
US7238357B2 (en) 2007-07-03
JP2006512316A (ja) 2006-04-13
EP1558279B1 (en) 2010-01-06
AU2003286901A1 (en) 2004-06-07
DE60330889D1 (de) 2010-02-25
KR101072179B1 (ko) 2011-10-10
AU2003286901B2 (en) 2008-06-12
ES2337892T3 (es) 2010-04-30
BR0315979A (pt) 2005-09-20
ATE454162T1 (de) 2010-01-15
WO2004041303B1 (en) 2004-10-14
CN1711103A (zh) 2005-12-21
EP1558279A1 (en) 2005-08-03

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued